| Full name: F-box protein 38 | Alias Symbol: MOKA|SP329|FLJ13962|Fbx38 | ||
| Type: protein-coding gene | Cytoband: 5q32 | ||
| Entrez ID: 81545 | HGNC ID: HGNC:28844 | Ensembl Gene: ENSG00000145868 | OMIM ID: 608533 |
| Drug and gene relationship at DGIdb | |||
Expression of FBXO38:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO38 | 81545 | 224369_s_at | -0.1656 | 0.5091 | |
| GSE20347 | FBXO38 | 81545 | 221257_x_at | -0.3302 | 0.0028 | |
| GSE23400 | FBXO38 | 81545 | 221257_x_at | -0.0487 | 0.4857 | |
| GSE26886 | FBXO38 | 81545 | 221257_x_at | -0.0035 | 0.9887 | |
| GSE29001 | FBXO38 | 81545 | 221257_x_at | -0.1633 | 0.3990 | |
| GSE38129 | FBXO38 | 81545 | 221257_x_at | -0.3365 | 0.0006 | |
| GSE45670 | FBXO38 | 81545 | 221257_x_at | -0.1246 | 0.3616 | |
| GSE53622 | FBXO38 | 81545 | 80954 | -0.1217 | 0.0038 | |
| GSE53624 | FBXO38 | 81545 | 80954 | -0.1691 | 0.0023 | |
| GSE63941 | FBXO38 | 81545 | 221257_x_at | -0.2501 | 0.5065 | |
| GSE77861 | FBXO38 | 81545 | 224369_s_at | 0.0936 | 0.6679 | |
| GSE97050 | FBXO38 | 81545 | A_23_P146811 | -0.0579 | 0.7878 | |
| SRP007169 | FBXO38 | 81545 | RNAseq | -0.1961 | 0.5881 | |
| SRP008496 | FBXO38 | 81545 | RNAseq | -0.4439 | 0.0255 | |
| SRP064894 | FBXO38 | 81545 | RNAseq | -0.1060 | 0.5418 | |
| SRP133303 | FBXO38 | 81545 | RNAseq | -0.0490 | 0.6773 | |
| SRP159526 | FBXO38 | 81545 | RNAseq | -0.3253 | 0.3649 | |
| SRP193095 | FBXO38 | 81545 | RNAseq | -0.2793 | 0.0005 | |
| SRP219564 | FBXO38 | 81545 | RNAseq | -0.2914 | 0.1582 | |
| TCGA | FBXO38 | 81545 | RNAseq | -0.1656 | 0.0006 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO38 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO38:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO38 | 81545 | 1 | 12 | 17 | |
| GSE20123 | FBXO38 | 81545 | 1 | 13 | 16 | |
| GSE43470 | FBXO38 | 81545 | 2 | 9 | 32 | |
| GSE46452 | FBXO38 | 81545 | 0 | 27 | 32 | |
| GSE47630 | FBXO38 | 81545 | 0 | 20 | 20 | |
| GSE54993 | FBXO38 | 81545 | 9 | 1 | 60 | |
| GSE54994 | FBXO38 | 81545 | 2 | 15 | 36 | |
| GSE60625 | FBXO38 | 81545 | 0 | 0 | 11 | |
| GSE74703 | FBXO38 | 81545 | 2 | 7 | 27 | |
| GSE74704 | FBXO38 | 81545 | 1 | 8 | 11 | |
| TCGA | FBXO38 | 81545 | 5 | 38 | 53 |
Total number of gains: 23; Total number of losses: 150; Total Number of normals: 315.
Somatic mutations of FBXO38:
Generating mutation plots.
Highly correlated genes for FBXO38:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO38 | SLC35C1 | 0.685066 | 3 | 0 | 3 |
| FBXO38 | SSTR2 | 0.682179 | 3 | 0 | 3 |
| FBXO38 | SETDB2 | 0.681911 | 3 | 0 | 3 |
| FBXO38 | ATP6V0A4 | 0.651103 | 3 | 0 | 3 |
| FBXO38 | NCKAP5 | 0.643463 | 4 | 0 | 3 |
| FBXO38 | BAHCC1 | 0.630934 | 4 | 0 | 3 |
| FBXO38 | COL20A1 | 0.622308 | 3 | 0 | 3 |
| FBXO38 | CYB5D2 | 0.613898 | 3 | 0 | 3 |
| FBXO38 | CHRNA4 | 0.611947 | 3 | 0 | 3 |
| FBXO38 | DNAJC17 | 0.605398 | 4 | 0 | 3 |
| FBXO38 | KRT24 | 0.594572 | 4 | 0 | 3 |
| FBXO38 | CREBRF | 0.585895 | 4 | 0 | 3 |
| FBXO38 | HDAC4 | 0.579422 | 4 | 0 | 3 |
| FBXO38 | EPS8L2 | 0.577622 | 4 | 0 | 4 |
| FBXO38 | NET1 | 0.575984 | 3 | 0 | 3 |
| FBXO38 | MRPL22 | 0.575124 | 5 | 0 | 3 |
| FBXO38 | AGPAT2 | 0.57471 | 4 | 0 | 3 |
| FBXO38 | SEC24A | 0.558948 | 7 | 0 | 3 |
| FBXO38 | TTC1 | 0.558669 | 8 | 0 | 5 |
| FBXO38 | TRAPPC13 | 0.553149 | 9 | 0 | 5 |
For details and further investigation, click here
