| Full name: DnaJ heat shock protein family (Hsp40) member C28 | Alias Symbol: C21orf78 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 54943 | HGNC ID: HGNC:1297 | Ensembl Gene: ENSG00000177692 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC28 | 54943 | 220372_at | -0.2636 | 0.2566 | |
| GSE20347 | DNAJC28 | 54943 | 220372_at | -0.1961 | 0.0022 | |
| GSE23400 | DNAJC28 | 54943 | 220372_at | -0.0702 | 0.0006 | |
| GSE26886 | DNAJC28 | 54943 | 220372_at | -0.2056 | 0.0754 | |
| GSE29001 | DNAJC28 | 54943 | 220372_at | -0.2049 | 0.4193 | |
| GSE38129 | DNAJC28 | 54943 | 220372_at | -0.2296 | 0.0001 | |
| GSE45670 | DNAJC28 | 54943 | 220372_at | -0.1497 | 0.2582 | |
| GSE53622 | DNAJC28 | 54943 | 99093 | -1.0552 | 0.0000 | |
| GSE53624 | DNAJC28 | 54943 | 99093 | -0.9180 | 0.0000 | |
| GSE63941 | DNAJC28 | 54943 | 220372_at | 0.0960 | 0.7530 | |
| GSE77861 | DNAJC28 | 54943 | 220372_at | -0.2113 | 0.0172 | |
| GSE97050 | DNAJC28 | 54943 | A_23_P68700 | -0.1822 | 0.3344 | |
| SRP133303 | DNAJC28 | 54943 | RNAseq | -1.2231 | 0.0000 | |
| SRP159526 | DNAJC28 | 54943 | RNAseq | -0.7612 | 0.0241 | |
| SRP193095 | DNAJC28 | 54943 | RNAseq | -1.2183 | 0.0000 | |
| SRP219564 | DNAJC28 | 54943 | RNAseq | -1.3977 | 0.0095 | |
| TCGA | DNAJC28 | 54943 | RNAseq | -0.8910 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by DNAJC28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC28 | 54943 | 2 | 8 | 20 | |
| GSE20123 | DNAJC28 | 54943 | 2 | 9 | 19 | |
| GSE43470 | DNAJC28 | 54943 | 3 | 9 | 31 | |
| GSE46452 | DNAJC28 | 54943 | 1 | 21 | 37 | |
| GSE47630 | DNAJC28 | 54943 | 6 | 17 | 17 | |
| GSE54993 | DNAJC28 | 54943 | 9 | 1 | 60 | |
| GSE54994 | DNAJC28 | 54943 | 1 | 9 | 43 | |
| GSE60625 | DNAJC28 | 54943 | 0 | 0 | 11 | |
| GSE74703 | DNAJC28 | 54943 | 3 | 6 | 27 | |
| GSE74704 | DNAJC28 | 54943 | 1 | 4 | 15 | |
| TCGA | DNAJC28 | 54943 | 9 | 35 | 52 |
Total number of gains: 37; Total number of losses: 119; Total Number of normals: 332.
Somatic mutations of DNAJC28:
Generating mutation plots.
Highly correlated genes for DNAJC28:
Showing top 20/1065 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC28 | PDCD4 | 0.785904 | 3 | 0 | 3 |
| DNAJC28 | TPTE | 0.767056 | 3 | 0 | 3 |
| DNAJC28 | CETN2 | 0.728754 | 3 | 0 | 3 |
| DNAJC28 | ZNF790 | 0.724835 | 3 | 0 | 3 |
| DNAJC28 | ICA1L | 0.720515 | 3 | 0 | 3 |
| DNAJC28 | RSPH3 | 0.706715 | 4 | 0 | 4 |
| DNAJC28 | SPA17 | 0.706426 | 3 | 0 | 3 |
| DNAJC28 | ZNF700 | 0.70387 | 3 | 0 | 3 |
| DNAJC28 | ALKBH7 | 0.70313 | 5 | 0 | 5 |
| DNAJC28 | FAM162B | 0.697983 | 3 | 0 | 3 |
| DNAJC28 | BRWD1 | 0.697257 | 5 | 0 | 5 |
| DNAJC28 | ZNF35 | 0.687719 | 3 | 0 | 3 |
| DNAJC28 | CCNYL1 | 0.685923 | 4 | 0 | 4 |
| DNAJC28 | ZNF846 | 0.685545 | 3 | 0 | 3 |
| DNAJC28 | ABHD12 | 0.684423 | 3 | 0 | 3 |
| DNAJC28 | TRIM33 | 0.679186 | 4 | 0 | 3 |
| DNAJC28 | CA13 | 0.678251 | 3 | 0 | 3 |
| DNAJC28 | BRAP | 0.678173 | 3 | 0 | 3 |
| DNAJC28 | KBTBD3 | 0.677809 | 4 | 0 | 3 |
| DNAJC28 | SETMAR | 0.677226 | 4 | 0 | 4 |
For details and further investigation, click here
