| Full name: transmembrane phosphatase with tensin homology | Alias Symbol: PTEN2|CT44 | ||
| Type: protein-coding gene | Cytoband: 21p11.2 | ||
| Entrez ID: 7179 | HGNC ID: HGNC:12023 | Ensembl Gene: ENSG00000274391 | OMIM ID: 604336 |
Expression of TPTE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TPTE | 7179 | 220205_at | -0.1109 | 0.5336 | |
| GSE20347 | TPTE | 7179 | 220205_at | -0.0202 | 0.7457 | |
| GSE23400 | TPTE | 7179 | 220205_at | 0.1349 | 0.2790 | |
| GSE26886 | TPTE | 7179 | 220205_at | -0.0281 | 0.7177 | |
| GSE29001 | TPTE | 7179 | 220205_at | 0.2234 | 0.6291 | |
| GSE38129 | TPTE | 7179 | 220205_at | 0.0195 | 0.7363 | |
| GSE45670 | TPTE | 7179 | 220205_at | 0.3175 | 0.3563 | |
| GSE63941 | TPTE | 7179 | 220205_at | 0.2946 | 0.7495 | |
| GSE77861 | TPTE | 7179 | 220205_at | -0.0189 | 0.8175 | |
| GSE97050 | TPTE | 7179 | A_33_P3247392 | -0.6056 | 0.1861 | |
| TCGA | TPTE | 7179 | RNAseq | -0.8940 | 0.4902 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TPTE expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TPTE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TPTE | 7179 | 2 | 9 | 19 | |
| GSE20123 | TPTE | 7179 | 2 | 9 | 19 | |
| GSE43470 | TPTE | 7179 | 1 | 13 | 29 | |
| GSE46452 | TPTE | 7179 | 1 | 22 | 36 | |
| GSE47630 | TPTE | 7179 | 5 | 21 | 14 | |
| GSE54993 | TPTE | 7179 | 10 | 1 | 59 | |
| GSE54994 | TPTE | 7179 | 3 | 10 | 40 | |
| GSE60625 | TPTE | 7179 | 0 | 0 | 11 | |
| GSE74703 | TPTE | 7179 | 1 | 11 | 24 | |
| GSE74704 | TPTE | 7179 | 2 | 6 | 12 | |
| TCGA | TPTE | 7179 | 15 | 41 | 40 |
Total number of gains: 42; Total number of losses: 143; Total Number of normals: 303.
Somatic mutations of TPTE:
Generating mutation plots.
Highly correlated genes for TPTE:
Showing all 20 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TPTE | DNAJC28 | 0.767056 | 3 | 0 | 3 |
| TPTE | ZRANB1 | 0.7377 | 3 | 0 | 3 |
| TPTE | IMPACT | 0.689123 | 3 | 0 | 3 |
| TPTE | FBXO36 | 0.68305 | 3 | 0 | 3 |
| TPTE | MSH3 | 0.674659 | 3 | 0 | 3 |
| TPTE | PRDM2 | 0.673789 | 3 | 0 | 3 |
| TPTE | ARSG | 0.664875 | 3 | 0 | 3 |
| TPTE | OR7A10 | 0.630967 | 4 | 0 | 3 |
| TPTE | MAGEC1 | 0.621694 | 4 | 0 | 3 |
| TPTE | ROPN1 | 0.617453 | 4 | 0 | 3 |
| TPTE | RPLP2 | 0.591591 | 4 | 0 | 3 |
| TPTE | MYT1 | 0.583654 | 4 | 0 | 3 |
| TPTE | PRMT2 | 0.575499 | 5 | 0 | 4 |
| TPTE | SIGLEC6 | 0.558006 | 4 | 0 | 3 |
| TPTE | UTY | 0.556408 | 5 | 0 | 3 |
| TPTE | HOXC5 | 0.549038 | 5 | 0 | 3 |
| TPTE | SH3GL3 | 0.532559 | 3 | 0 | 3 |
| TPTE | KCNJ14 | 0.529295 | 4 | 0 | 3 |
| TPTE | CLC | 0.515849 | 4 | 0 | 3 |
| TPTE | RPS11 | 0.502658 | 5 | 0 | 3 |
For details and further investigation, click here
