| Full name: islet cell autoantigen 1 like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q33.2 | ||
| Entrez ID: 130026 | HGNC ID: HGNC:14442 | Ensembl Gene: ENSG00000163596 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ICA1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ICA1L | 130026 | 230454_at | -0.8016 | 0.2838 | |
| GSE26886 | ICA1L | 130026 | 1554205_s_at | -0.1316 | 0.1666 | |
| GSE45670 | ICA1L | 130026 | 230454_at | -0.8888 | 0.0021 | |
| GSE53622 | ICA1L | 130026 | 238 | -0.2967 | 0.0590 | |
| GSE53624 | ICA1L | 130026 | 238 | -0.1456 | 0.2866 | |
| GSE63941 | ICA1L | 130026 | 230454_at | -1.2966 | 0.0411 | |
| GSE77861 | ICA1L | 130026 | 223881_at | -0.1908 | 0.0287 | |
| GSE97050 | ICA1L | 130026 | A_24_P211797 | -0.6886 | 0.1637 | |
| SRP007169 | ICA1L | 130026 | RNAseq | 0.3486 | 0.6179 | |
| SRP008496 | ICA1L | 130026 | RNAseq | 2.1663 | 0.0001 | |
| SRP064894 | ICA1L | 130026 | RNAseq | -0.0830 | 0.7403 | |
| SRP133303 | ICA1L | 130026 | RNAseq | -0.3415 | 0.1854 | |
| SRP159526 | ICA1L | 130026 | RNAseq | 0.2501 | 0.4248 | |
| SRP193095 | ICA1L | 130026 | RNAseq | 0.3922 | 0.0306 | |
| SRP219564 | ICA1L | 130026 | RNAseq | 0.0218 | 0.9700 | |
| TCGA | ICA1L | 130026 | RNAseq | -0.3908 | 0.0135 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ICA1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ICA1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ICA1L | 130026 | 7 | 4 | 19 | |
| GSE20123 | ICA1L | 130026 | 7 | 4 | 19 | |
| GSE43470 | ICA1L | 130026 | 2 | 3 | 38 | |
| GSE46452 | ICA1L | 130026 | 1 | 4 | 54 | |
| GSE47630 | ICA1L | 130026 | 4 | 5 | 31 | |
| GSE54993 | ICA1L | 130026 | 0 | 3 | 67 | |
| GSE54994 | ICA1L | 130026 | 10 | 8 | 35 | |
| GSE60625 | ICA1L | 130026 | 0 | 3 | 8 | |
| GSE74703 | ICA1L | 130026 | 2 | 2 | 32 | |
| GSE74704 | ICA1L | 130026 | 3 | 2 | 15 | |
| TCGA | ICA1L | 130026 | 21 | 12 | 63 |
Total number of gains: 57; Total number of losses: 50; Total Number of normals: 381.
Somatic mutations of ICA1L:
Generating mutation plots.
Highly correlated genes for ICA1L:
Showing top 20/673 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ICA1L | WSCD2 | 0.828089 | 3 | 0 | 3 |
| ICA1L | CRBN | 0.821518 | 4 | 0 | 4 |
| ICA1L | HNRNPH3 | 0.812427 | 3 | 0 | 3 |
| ICA1L | PNKD | 0.797184 | 3 | 0 | 3 |
| ICA1L | CDC16 | 0.795442 | 3 | 0 | 3 |
| ICA1L | ACTR1A | 0.78814 | 3 | 0 | 3 |
| ICA1L | BAG1 | 0.770978 | 3 | 0 | 3 |
| ICA1L | ZNF214 | 0.765605 | 3 | 0 | 3 |
| ICA1L | MSRB2 | 0.764564 | 4 | 0 | 3 |
| ICA1L | DTNA | 0.762224 | 4 | 0 | 4 |
| ICA1L | LYRM1 | 0.761982 | 3 | 0 | 3 |
| ICA1L | ZMYND11 | 0.759283 | 5 | 0 | 5 |
| ICA1L | UBE4B | 0.748893 | 3 | 0 | 3 |
| ICA1L | UBXN10 | 0.748493 | 4 | 0 | 3 |
| ICA1L | ALDH6A1 | 0.745724 | 4 | 0 | 4 |
| ICA1L | FNIP2 | 0.745393 | 3 | 0 | 3 |
| ICA1L | CRYL1 | 0.743784 | 3 | 0 | 3 |
| ICA1L | LIX1L | 0.743757 | 3 | 0 | 3 |
| ICA1L | TMEM114 | 0.740046 | 3 | 0 | 3 |
| ICA1L | WWTR1 | 0.739313 | 4 | 0 | 4 |
For details and further investigation, click here
