RSPH3

 

Full name: radial spoke head 3 Alias Symbol: dJ111C20.1|RSP3
Type: protein-coding gene Cytoband: 6q25.3
Entrez ID: 83861 HGNC ID: HGNC:21054 Ensembl Gene: ENSG00000130363 OMIM ID: 615876
Drug and gene relationship at DGIdb

 

Expression of RSPH3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RSPH3 83861 1568613_at 0.0154 0.9656
GSE26886 RSPH3 83861 1568613_at 0.0083 0.9619
GSE45670 RSPH3 83861 235889_at -0.5834 0.0016
GSE53622 RSPH3 83861 68262 -0.9926 0.0000
GSE53624 RSPH3 83861 68262 -1.1154 0.0000
GSE63941 RSPH3 83861 1568613_at 0.4995 0.0044
GSE77861 RSPH3 83861 1568613_at -0.0457 0.6203
GSE97050 RSPH3 83861 A_23_P59397 -0.4737 0.1616
SRP007169 RSPH3 83861 RNAseq -1.5977 0.0000
SRP008496 RSPH3 83861 RNAseq -1.3379 0.0000
SRP064894 RSPH3 83861 RNAseq -0.6717 0.0001
SRP133303 RSPH3 83861 RNAseq -0.4493 0.0064
SRP159526 RSPH3 83861 RNAseq -1.1299 0.0001
SRP193095 RSPH3 83861 RNAseq -0.8370 0.0000
SRP219564 RSPH3 83861 RNAseq -0.7835 0.0310
TCGA RSPH3 83861 RNAseq -0.0236 0.7363

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by RSPH3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RSPH3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RSPH3 83861 3 5 22
GSE20123 RSPH3 83861 3 4 23
GSE43470 RSPH3 83861 3 0 40
GSE46452 RSPH3 83861 3 10 46
GSE47630 RSPH3 83861 9 4 27
GSE54993 RSPH3 83861 3 2 65
GSE54994 RSPH3 83861 8 8 37
GSE60625 RSPH3 83861 0 1 10
GSE74703 RSPH3 83861 3 0 33
GSE74704 RSPH3 83861 1 2 17
TCGA RSPH3 83861 13 22 61

Total number of gains: 49; Total number of losses: 58; Total Number of normals: 381.  


 

Somatic mutations of RSPH3:

 

Generating mutation plots.

 

Highly correlated genes for RSPH3:

 

Showing top 20/715 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RSPH3DOCK90.814337404
RSPH3WASF20.789971303
RSPH3SLC46A20.786338404
RSPH3HECA0.777706404
RSPH3FCER1A0.776753404
RSPH3CCNG20.771761404
RSPH3RABGGTA0.764978303
RSPH3STK390.76333404
RSPH3PALMD0.762072404
RSPH3TMOD30.759933303
RSPH3LMBRD10.75847404
RSPH3CCDC60.757153404
RSPH3ARHGEF10L0.756638404
RSPH3FAM166A0.756557303
RSPH3MRPS360.754557404
RSPH3RNF100.750203404
RSPH3AHNAK0.747175303
RSPH3CHMP2B0.746964404
RSPH3CAB39L0.746572404
RSPH3CPPED10.746548404

For details and further investigation, click here