| Full name: abhydrolase domain containing 12 | Alias Symbol: DKFZP434P106|dJ965G21.2|BEM46L2|ABHD12A | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 26090 | HGNC ID: HGNC:15868 | Ensembl Gene: ENSG00000100997 | OMIM ID: 613599 |
| Drug and gene relationship at DGIdb | |||
Expression of ABHD12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABHD12 | 26090 | 228123_s_at | -0.0796 | 0.9239 | |
| GSE26886 | ABHD12 | 26090 | 228124_at | -0.6478 | 0.0048 | |
| GSE45670 | ABHD12 | 26090 | 228124_at | -0.5264 | 0.0777 | |
| GSE63941 | ABHD12 | 26090 | 228123_s_at | 1.3502 | 0.0124 | |
| GSE77861 | ABHD12 | 26090 | 228123_s_at | -0.6338 | 0.0846 | |
| GSE97050 | ABHD12 | 26090 | A_23_P149494 | 0.2068 | 0.7191 | |
| SRP007169 | ABHD12 | 26090 | RNAseq | -2.5631 | 0.0000 | |
| SRP008496 | ABHD12 | 26090 | RNAseq | -2.3594 | 0.0000 | |
| SRP064894 | ABHD12 | 26090 | RNAseq | -0.6978 | 0.0014 | |
| SRP133303 | ABHD12 | 26090 | RNAseq | -0.4507 | 0.0001 | |
| SRP159526 | ABHD12 | 26090 | RNAseq | -0.2398 | 0.1404 | |
| SRP193095 | ABHD12 | 26090 | RNAseq | -0.8878 | 0.0000 | |
| SRP219564 | ABHD12 | 26090 | RNAseq | -0.1828 | 0.7096 | |
| TCGA | ABHD12 | 26090 | RNAseq | -0.1022 | 0.0428 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by ABHD12 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ABHD12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABHD12 | 26090 | 12 | 2 | 16 | |
| GSE20123 | ABHD12 | 26090 | 12 | 2 | 16 | |
| GSE43470 | ABHD12 | 26090 | 11 | 1 | 31 | |
| GSE46452 | ABHD12 | 26090 | 27 | 1 | 31 | |
| GSE47630 | ABHD12 | 26090 | 17 | 4 | 19 | |
| GSE54993 | ABHD12 | 26090 | 0 | 17 | 53 | |
| GSE54994 | ABHD12 | 26090 | 27 | 1 | 25 | |
| GSE60625 | ABHD12 | 26090 | 0 | 0 | 11 | |
| GSE74703 | ABHD12 | 26090 | 10 | 1 | 25 | |
| GSE74704 | ABHD12 | 26090 | 7 | 1 | 12 | |
| TCGA | ABHD12 | 26090 | 46 | 9 | 41 |
Total number of gains: 169; Total number of losses: 39; Total Number of normals: 280.
Somatic mutations of ABHD12:
Generating mutation plots.
Highly correlated genes for ABHD12:
Showing top 20/526 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABHD12 | RALGAPA2 | 0.7908 | 3 | 0 | 3 |
| ABHD12 | FAM107B | 0.788544 | 3 | 0 | 3 |
| ABHD12 | RBM20 | 0.747435 | 3 | 0 | 3 |
| ABHD12 | STK38 | 0.744293 | 3 | 0 | 3 |
| ABHD12 | RBPMS-AS1 | 0.732585 | 3 | 0 | 3 |
| ABHD12 | ARFIP1 | 0.729036 | 3 | 0 | 3 |
| ABHD12 | ZNF416 | 0.719451 | 4 | 0 | 4 |
| ABHD12 | TSC22D4 | 0.718476 | 3 | 0 | 3 |
| ABHD12 | GTPBP2 | 0.718376 | 3 | 0 | 3 |
| ABHD12 | ZNF212 | 0.717755 | 4 | 0 | 4 |
| ABHD12 | NHSL1 | 0.715082 | 3 | 0 | 3 |
| ABHD12 | METAP1 | 0.699302 | 5 | 0 | 4 |
| ABHD12 | OSBPL2 | 0.69914 | 4 | 0 | 4 |
| ABHD12 | ALDH1A3 | 0.69768 | 3 | 0 | 3 |
| ABHD12 | DHX32 | 0.696158 | 3 | 0 | 3 |
| ABHD12 | MBNL3 | 0.695094 | 4 | 0 | 4 |
| ABHD12 | DCAF10 | 0.692181 | 3 | 0 | 3 |
| ABHD12 | LPIN2 | 0.689984 | 4 | 0 | 3 |
| ABHD12 | FRAT1 | 0.688668 | 3 | 0 | 3 |
| ABHD12 | DNAJC28 | 0.684423 | 3 | 0 | 3 |
For details and further investigation, click here
