TRIM33

 

Full name: tripartite motif containing 33 Alias Symbol: TIF1GAMMA|FLJ11429|KIAA1113|TIFGAMMA|RFG7|TF1G|TIF1G|PTC7
Type: protein-coding gene Cytoband: 1p13.2
Entrez ID: 51592 HGNC ID: HGNC:16290 Ensembl Gene: ENSG00000197323 OMIM ID: 605769
Drug and gene relationship at DGIdb
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of TRIM33:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TRIM33 51592 210266_s_at -0.2246 0.5062
GSE20347 TRIM33 51592 210266_s_at -0.2922 0.1473
GSE23400 TRIM33 51592 210266_s_at -0.2049 0.0014
GSE26886 TRIM33 51592 212435_at -0.6730 0.0018
GSE29001 TRIM33 51592 210266_s_at -0.3718 0.2146
GSE38129 TRIM33 51592 210266_s_at -0.2367 0.1415
GSE45670 TRIM33 51592 210266_s_at -0.1703 0.2821
GSE53622 TRIM33 51592 8797 -0.6248 0.0000
GSE53624 TRIM33 51592 8797 -0.4355 0.0000
GSE63941 TRIM33 51592 212435_at 0.2821 0.6974
GSE77861 TRIM33 51592 210266_s_at -0.0701 0.8101
GSE97050 TRIM33 51592 A_33_P3257367 -0.5421 0.1095
SRP007169 TRIM33 51592 RNAseq -0.0330 0.9290
SRP008496 TRIM33 51592 RNAseq -0.0994 0.5878
SRP064894 TRIM33 51592 RNAseq -0.3013 0.1050
SRP133303 TRIM33 51592 RNAseq -0.1378 0.1550
SRP159526 TRIM33 51592 RNAseq -0.7035 0.0067
SRP193095 TRIM33 51592 RNAseq -0.3353 0.0000
SRP219564 TRIM33 51592 RNAseq -0.6703 0.1289
TCGA TRIM33 51592 RNAseq -0.0729 0.1122

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by TRIM33 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of TRIM33:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TRIM33 51592 0 9 21
GSE20123 TRIM33 51592 0 9 21
GSE43470 TRIM33 51592 0 8 35
GSE46452 TRIM33 51592 2 1 56
GSE47630 TRIM33 51592 9 5 26
GSE54993 TRIM33 51592 0 1 69
GSE54994 TRIM33 51592 7 3 43
GSE60625 TRIM33 51592 0 0 11
GSE74703 TRIM33 51592 0 7 29
GSE74704 TRIM33 51592 0 5 15
TCGA TRIM33 51592 11 30 55

Total number of gains: 29; Total number of losses: 78; Total Number of normals: 381.  


 

Somatic mutations of TRIM33:

 

Generating mutation plots.

 

Highly correlated genes for TRIM33:

 

Showing top 20/676 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TRIM33RNF2070.764646404
TRIM33CRBN0.734932303
TRIM33IGIP0.731262404
TRIM33FAM53B0.724678303
TRIM33MOCS20.724213303
TRIM33SSNA10.723662303
TRIM33ZACN0.721878303
TRIM33ALKBH70.715896303
TRIM33HDHD20.715312303
TRIM33RWDD2B0.713594403
TRIM33AKAP17A0.703532303
TRIM33RPS140.703443303
TRIM33ZNF5710.701928403
TRIM33FAM122A0.700706404
TRIM33SNX40.700588403
TRIM33ANKRA20.699651303
TRIM33CCDC70.699317303
TRIM33ATG140.698229303
TRIM33DNAJB120.696714404
TRIM33FAM174A0.690497403

For details and further investigation, click here