| Full name: aspartyl aminopeptidase | Alias Symbol: DAP|ASPEP | ||
| Type: protein-coding gene | Cytoband: 2q35 | ||
| Entrez ID: 23549 | HGNC ID: HGNC:2981 | Ensembl Gene: ENSG00000123992 | OMIM ID: 611367 |
| Drug and gene relationship at DGIdb | |||
Expression of DNPEP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNPEP | 23549 | 38703_at | 0.1642 | 0.5887 | |
| GSE20347 | DNPEP | 23549 | 38703_at | 0.1188 | 0.3592 | |
| GSE23400 | DNPEP | 23549 | 38703_at | 0.2362 | 0.0000 | |
| GSE26886 | DNPEP | 23549 | 38703_at | 0.6505 | 0.0000 | |
| GSE29001 | DNPEP | 23549 | 38703_at | 0.1556 | 0.4499 | |
| GSE38129 | DNPEP | 23549 | 38703_at | 0.1052 | 0.2988 | |
| GSE45670 | DNPEP | 23549 | 38703_at | 0.1951 | 0.1604 | |
| GSE53622 | DNPEP | 23549 | 81139 | 0.3118 | 0.0000 | |
| GSE53624 | DNPEP | 23549 | 81139 | 0.2952 | 0.0006 | |
| GSE63941 | DNPEP | 23549 | 38703_at | 0.2726 | 0.4348 | |
| GSE77861 | DNPEP | 23549 | 38703_at | 0.2919 | 0.0228 | |
| GSE97050 | DNPEP | 23549 | A_24_P231494 | 0.1629 | 0.4877 | |
| SRP007169 | DNPEP | 23549 | RNAseq | 0.1324 | 0.7263 | |
| SRP008496 | DNPEP | 23549 | RNAseq | 0.3070 | 0.2049 | |
| SRP064894 | DNPEP | 23549 | RNAseq | 0.3396 | 0.1098 | |
| SRP133303 | DNPEP | 23549 | RNAseq | 0.2120 | 0.2931 | |
| SRP159526 | DNPEP | 23549 | RNAseq | 0.3356 | 0.1320 | |
| SRP193095 | DNPEP | 23549 | RNAseq | 0.0508 | 0.7373 | |
| SRP219564 | DNPEP | 23549 | RNAseq | 0.2625 | 0.2610 | |
| TCGA | DNPEP | 23549 | RNAseq | 0.0147 | 0.7568 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNPEP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNPEP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNPEP | 23549 | 2 | 14 | 14 | |
| GSE20123 | DNPEP | 23549 | 2 | 13 | 15 | |
| GSE43470 | DNPEP | 23549 | 1 | 6 | 36 | |
| GSE46452 | DNPEP | 23549 | 0 | 5 | 54 | |
| GSE47630 | DNPEP | 23549 | 4 | 5 | 31 | |
| GSE54993 | DNPEP | 23549 | 1 | 2 | 67 | |
| GSE54994 | DNPEP | 23549 | 8 | 9 | 36 | |
| GSE60625 | DNPEP | 23549 | 0 | 3 | 8 | |
| GSE74703 | DNPEP | 23549 | 1 | 5 | 30 | |
| GSE74704 | DNPEP | 23549 | 2 | 7 | 11 | |
| TCGA | DNPEP | 23549 | 13 | 25 | 58 |
Total number of gains: 34; Total number of losses: 94; Total Number of normals: 360.
Somatic mutations of DNPEP:
Generating mutation plots.
Highly correlated genes for DNPEP:
Showing top 20/900 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNPEP | ADCY3 | 0.811052 | 3 | 0 | 3 |
| DNPEP | CCT8 | 0.803632 | 3 | 0 | 3 |
| DNPEP | TRADD | 0.793561 | 3 | 0 | 3 |
| DNPEP | ANKRD9 | 0.791233 | 3 | 0 | 3 |
| DNPEP | TLN2 | 0.784371 | 3 | 0 | 3 |
| DNPEP | AGMAT | 0.770429 | 3 | 0 | 3 |
| DNPEP | C1orf216 | 0.770399 | 4 | 0 | 4 |
| DNPEP | NAF1 | 0.767957 | 3 | 0 | 3 |
| DNPEP | ZNF121 | 0.766247 | 3 | 0 | 3 |
| DNPEP | CASK | 0.765704 | 3 | 0 | 3 |
| DNPEP | C15orf61 | 0.764134 | 4 | 0 | 4 |
| DNPEP | RPL7L1 | 0.760955 | 3 | 0 | 3 |
| DNPEP | KLHL5 | 0.758854 | 3 | 0 | 3 |
| DNPEP | SSBP4 | 0.753523 | 3 | 0 | 3 |
| DNPEP | CYB5D1 | 0.747769 | 3 | 0 | 3 |
| DNPEP | FOXJ2 | 0.74253 | 3 | 0 | 3 |
| DNPEP | LRRC58 | 0.738715 | 4 | 0 | 4 |
| DNPEP | CEP63 | 0.730153 | 4 | 0 | 4 |
| DNPEP | MSTO1 | 0.729967 | 3 | 0 | 3 |
| DNPEP | C7orf50 | 0.728687 | 4 | 0 | 4 |
For details and further investigation, click here
