| Full name: chaperonin containing TCP1 subunit 8 | Alias Symbol: Cctq|PRED71 | ||
| Type: protein-coding gene | Cytoband: 21q21.3 | ||
| Entrez ID: 10694 | HGNC ID: HGNC:1623 | Ensembl Gene: ENSG00000156261 | OMIM ID: 617786 |
| Drug and gene relationship at DGIdb | |||
Expression of CCT8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCT8 | 10694 | 200873_s_at | 0.3058 | 0.4515 | |
| GSE20347 | CCT8 | 10694 | 200873_s_at | 0.2993 | 0.0515 | |
| GSE23400 | CCT8 | 10694 | 200873_s_at | 0.4825 | 0.0000 | |
| GSE26886 | CCT8 | 10694 | 200873_s_at | 0.1628 | 0.3654 | |
| GSE29001 | CCT8 | 10694 | 200873_s_at | 0.2843 | 0.2622 | |
| GSE38129 | CCT8 | 10694 | 200873_s_at | 0.4606 | 0.0001 | |
| GSE45670 | CCT8 | 10694 | 200873_s_at | 0.2236 | 0.0908 | |
| GSE53622 | CCT8 | 10694 | 11405 | 0.1594 | 0.0037 | |
| GSE53624 | CCT8 | 10694 | 11405 | 0.4098 | 0.0000 | |
| GSE63941 | CCT8 | 10694 | 200873_s_at | 0.0473 | 0.9048 | |
| GSE77861 | CCT8 | 10694 | 200873_s_at | 0.0063 | 0.9807 | |
| GSE97050 | CCT8 | 10694 | A_23_P102876 | 0.3315 | 0.3046 | |
| SRP007169 | CCT8 | 10694 | RNAseq | -0.5929 | 0.0450 | |
| SRP008496 | CCT8 | 10694 | RNAseq | -0.3068 | 0.1183 | |
| SRP064894 | CCT8 | 10694 | RNAseq | 0.3004 | 0.1147 | |
| SRP133303 | CCT8 | 10694 | RNAseq | 0.0598 | 0.7357 | |
| SRP159526 | CCT8 | 10694 | RNAseq | 0.0441 | 0.8882 | |
| SRP193095 | CCT8 | 10694 | RNAseq | -0.2344 | 0.0227 | |
| SRP219564 | CCT8 | 10694 | RNAseq | -0.3690 | 0.1139 | |
| TCGA | CCT8 | 10694 | RNAseq | 0.1176 | 0.0119 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CCT8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CCT8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCT8 | 10694 | 2 | 10 | 18 | |
| GSE20123 | CCT8 | 10694 | 2 | 10 | 18 | |
| GSE43470 | CCT8 | 10694 | 1 | 7 | 35 | |
| GSE46452 | CCT8 | 10694 | 1 | 21 | 37 | |
| GSE47630 | CCT8 | 10694 | 6 | 17 | 17 | |
| GSE54993 | CCT8 | 10694 | 9 | 1 | 60 | |
| GSE54994 | CCT8 | 10694 | 1 | 9 | 43 | |
| GSE60625 | CCT8 | 10694 | 0 | 0 | 11 | |
| GSE74703 | CCT8 | 10694 | 1 | 5 | 30 | |
| GSE74704 | CCT8 | 10694 | 2 | 6 | 12 | |
| TCGA | CCT8 | 10694 | 9 | 37 | 50 |
Total number of gains: 34; Total number of losses: 123; Total Number of normals: 331.
Somatic mutations of CCT8:
Generating mutation plots.
Highly correlated genes for CCT8:
Showing top 20/989 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCT8 | DNPEP | 0.803632 | 3 | 0 | 3 |
| CCT8 | NUDT19 | 0.771115 | 3 | 0 | 3 |
| CCT8 | C8orf76 | 0.760256 | 3 | 0 | 3 |
| CCT8 | CFHR3 | 0.744084 | 3 | 0 | 3 |
| CCT8 | SFSWAP | 0.743428 | 3 | 0 | 3 |
| CCT8 | ACBD5 | 0.727118 | 3 | 0 | 3 |
| CCT8 | ANAPC4 | 0.726435 | 3 | 0 | 3 |
| CCT8 | TCP1 | 0.720121 | 3 | 0 | 3 |
| CCT8 | SON | 0.720056 | 4 | 0 | 3 |
| CCT8 | CPNE1 | 0.715018 | 3 | 0 | 3 |
| CCT8 | SCML1 | 0.713781 | 3 | 0 | 3 |
| CCT8 | CDKN2C | 0.712773 | 3 | 0 | 3 |
| CCT8 | NOM1 | 0.711242 | 3 | 0 | 3 |
| CCT8 | EI24 | 0.70778 | 4 | 0 | 3 |
| CCT8 | RBMX | 0.707337 | 3 | 0 | 3 |
| CCT8 | MMACHC | 0.70485 | 4 | 0 | 4 |
| CCT8 | SEL1L | 0.702275 | 3 | 0 | 3 |
| CCT8 | CRLS1 | 0.702142 | 4 | 0 | 4 |
| CCT8 | INTS10 | 0.700426 | 4 | 0 | 4 |
| CCT8 | OTUD6B | 0.698263 | 4 | 0 | 3 |
For details and further investigation, click here
