| Full name: TNFRSF1A associated via death domain | Alias Symbol: Hs.89862 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 8717 | HGNC ID: HGNC:12030 | Ensembl Gene: ENSG00000102871 | OMIM ID: 603500 |
| Drug and gene relationship at DGIdb | |||
TRADD involved pathways:
Expression of TRADD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRADD | 8717 | 205641_s_at | 0.1037 | 0.6870 | |
| GSE20347 | TRADD | 8717 | 205641_s_at | -0.0552 | 0.5638 | |
| GSE23400 | TRADD | 8717 | 205641_s_at | -0.0048 | 0.9426 | |
| GSE26886 | TRADD | 8717 | 205641_s_at | 0.4663 | 0.0044 | |
| GSE29001 | TRADD | 8717 | 205641_s_at | -0.3193 | 0.0177 | |
| GSE38129 | TRADD | 8717 | 205641_s_at | 0.0341 | 0.7925 | |
| GSE45670 | TRADD | 8717 | 205641_s_at | 0.2123 | 0.0922 | |
| GSE53622 | TRADD | 8717 | 26477 | -0.1670 | 0.1044 | |
| GSE53624 | TRADD | 8717 | 26477 | -0.2487 | 0.0024 | |
| GSE63941 | TRADD | 8717 | 205641_s_at | 0.1820 | 0.6067 | |
| GSE77861 | TRADD | 8717 | 205641_s_at | 0.5256 | 0.0011 | |
| GSE97050 | TRADD | 8717 | A_23_P54649 | 0.2381 | 0.4460 | |
| SRP007169 | TRADD | 8717 | RNAseq | -1.1946 | 0.0010 | |
| SRP008496 | TRADD | 8717 | RNAseq | -1.0371 | 0.0013 | |
| SRP064894 | TRADD | 8717 | RNAseq | 0.1488 | 0.5968 | |
| SRP133303 | TRADD | 8717 | RNAseq | 0.1520 | 0.4293 | |
| SRP159526 | TRADD | 8717 | RNAseq | -0.4990 | 0.2323 | |
| SRP193095 | TRADD | 8717 | RNAseq | -0.0214 | 0.8764 | |
| SRP219564 | TRADD | 8717 | RNAseq | -0.1310 | 0.7136 | |
| TCGA | TRADD | 8717 | RNAseq | 0.0791 | 0.1942 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by TRADD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRADD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRADD | 8717 | 8 | 2 | 20 | |
| GSE20123 | TRADD | 8717 | 8 | 2 | 20 | |
| GSE43470 | TRADD | 8717 | 1 | 9 | 33 | |
| GSE46452 | TRADD | 8717 | 38 | 1 | 20 | |
| GSE47630 | TRADD | 8717 | 10 | 8 | 22 | |
| GSE54993 | TRADD | 8717 | 2 | 4 | 64 | |
| GSE54994 | TRADD | 8717 | 8 | 10 | 35 | |
| GSE60625 | TRADD | 8717 | 4 | 0 | 7 | |
| GSE74703 | TRADD | 8717 | 1 | 6 | 29 | |
| GSE74704 | TRADD | 8717 | 5 | 1 | 14 | |
| TCGA | TRADD | 8717 | 29 | 12 | 55 |
Total number of gains: 114; Total number of losses: 55; Total Number of normals: 319.
Somatic mutations of TRADD:
Generating mutation plots.
Highly correlated genes for TRADD:
Showing top 20/418 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRADD | PSMG3 | 0.812954 | 3 | 0 | 3 |
| TRADD | ITPA | 0.80977 | 3 | 0 | 3 |
| TRADD | DNPEP | 0.793561 | 3 | 0 | 3 |
| TRADD | MTX1 | 0.784262 | 3 | 0 | 3 |
| TRADD | MRPL55 | 0.772797 | 3 | 0 | 3 |
| TRADD | EIF2S2 | 0.772442 | 3 | 0 | 3 |
| TRADD | PRICKLE1 | 0.771666 | 3 | 0 | 3 |
| TRADD | SF3B2 | 0.766939 | 3 | 0 | 3 |
| TRADD | FCF1 | 0.766575 | 3 | 0 | 3 |
| TRADD | ADRM1 | 0.762845 | 3 | 0 | 3 |
| TRADD | TRMT6 | 0.7626 | 4 | 0 | 4 |
| TRADD | YIF1A | 0.761275 | 3 | 0 | 3 |
| TRADD | HPS5 | 0.759652 | 3 | 0 | 3 |
| TRADD | EXOSC6 | 0.756465 | 3 | 0 | 3 |
| TRADD | MAP4K4 | 0.7564 | 3 | 0 | 3 |
| TRADD | EFNB2 | 0.752659 | 3 | 0 | 3 |
| TRADD | WDR5 | 0.744397 | 3 | 0 | 3 |
| TRADD | LYST | 0.742728 | 3 | 0 | 3 |
| TRADD | GOPC | 0.739337 | 3 | 0 | 3 |
| TRADD | VAC14 | 0.731865 | 4 | 0 | 4 |
For details and further investigation, click here
