| Full name: nuclear assembly factor 1 ribonucleoprotein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q32.2 | ||
| Entrez ID: 92345 | HGNC ID: HGNC:25126 | Ensembl Gene: ENSG00000145414 | OMIM ID: 617868 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAF1 | 92345 | 244828_x_at | 0.5579 | 0.1535 | |
| GSE26886 | NAF1 | 92345 | 244828_x_at | 1.3293 | 0.0001 | |
| GSE45670 | NAF1 | 92345 | 244828_x_at | 0.2958 | 0.0311 | |
| GSE53622 | NAF1 | 92345 | 4525 | -0.1343 | 0.0929 | |
| GSE53624 | NAF1 | 92345 | 4525 | 0.0023 | 0.9802 | |
| GSE63941 | NAF1 | 92345 | 244828_x_at | 0.2383 | 0.6526 | |
| GSE77861 | NAF1 | 92345 | 244828_x_at | 0.3240 | 0.0290 | |
| GSE97050 | NAF1 | 92345 | A_24_P223163 | -0.0372 | 0.9113 | |
| SRP007169 | NAF1 | 92345 | RNAseq | 0.4543 | 0.3477 | |
| SRP008496 | NAF1 | 92345 | RNAseq | 0.5064 | 0.0766 | |
| SRP064894 | NAF1 | 92345 | RNAseq | -0.2810 | 0.2435 | |
| SRP133303 | NAF1 | 92345 | RNAseq | 0.4321 | 0.0105 | |
| SRP159526 | NAF1 | 92345 | RNAseq | 0.1742 | 0.5273 | |
| SRP193095 | NAF1 | 92345 | RNAseq | 0.1037 | 0.3670 | |
| SRP219564 | NAF1 | 92345 | RNAseq | -0.0919 | 0.7835 | |
| TCGA | NAF1 | 92345 | RNAseq | 0.0093 | 0.8800 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAF1 | 92345 | 0 | 12 | 18 | |
| GSE20123 | NAF1 | 92345 | 0 | 12 | 18 | |
| GSE43470 | NAF1 | 92345 | 0 | 14 | 29 | |
| GSE46452 | NAF1 | 92345 | 1 | 36 | 22 | |
| GSE47630 | NAF1 | 92345 | 0 | 22 | 18 | |
| GSE54993 | NAF1 | 92345 | 10 | 0 | 60 | |
| GSE54994 | NAF1 | 92345 | 1 | 12 | 40 | |
| GSE60625 | NAF1 | 92345 | 0 | 0 | 11 | |
| GSE74703 | NAF1 | 92345 | 0 | 12 | 24 | |
| GSE74704 | NAF1 | 92345 | 0 | 6 | 14 | |
| TCGA | NAF1 | 92345 | 10 | 35 | 51 |
Total number of gains: 22; Total number of losses: 161; Total Number of normals: 305.
Somatic mutations of NAF1:
Generating mutation plots.
Highly correlated genes for NAF1:
Showing top 20/762 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAF1 | UCKL1 | 0.828727 | 3 | 0 | 3 |
| NAF1 | BCORL1 | 0.797737 | 3 | 0 | 3 |
| NAF1 | RLIM | 0.794504 | 3 | 0 | 3 |
| NAF1 | FIP1L1 | 0.792098 | 3 | 0 | 3 |
| NAF1 | PPP1R16A | 0.788903 | 3 | 0 | 3 |
| NAF1 | NLK | 0.773634 | 3 | 0 | 3 |
| NAF1 | ULK1 | 0.770172 | 3 | 0 | 3 |
| NAF1 | DNPEP | 0.767957 | 3 | 0 | 3 |
| NAF1 | POLR2K | 0.767157 | 4 | 0 | 4 |
| NAF1 | CAMKK2 | 0.765714 | 3 | 0 | 3 |
| NAF1 | SMYD3 | 0.76058 | 3 | 0 | 3 |
| NAF1 | TAF1C | 0.758676 | 3 | 0 | 3 |
| NAF1 | CTBP2 | 0.757201 | 3 | 0 | 3 |
| NAF1 | MEA1 | 0.755008 | 3 | 0 | 3 |
| NAF1 | SFR1 | 0.754767 | 3 | 0 | 3 |
| NAF1 | DCP2 | 0.750882 | 3 | 0 | 3 |
| NAF1 | KLF11 | 0.748702 | 3 | 0 | 3 |
| NAF1 | PLAG1 | 0.747401 | 3 | 0 | 3 |
| NAF1 | MADD | 0.745592 | 3 | 0 | 3 |
| NAF1 | RPS6KC1 | 0.745062 | 3 | 0 | 3 |
For details and further investigation, click here
