| Full name: agmatinase | Alias Symbol: FLJ23384 | ||
| Type: protein-coding gene | Cytoband: 1p36.21 | ||
| Entrez ID: 79814 | HGNC ID: HGNC:18407 | Ensembl Gene: ENSG00000116771 | OMIM ID: 617887 |
| Drug and gene relationship at DGIdb | |||
Expression of AGMAT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AGMAT | 79814 | 221648_s_at | 1.1424 | 0.1557 | |
| GSE20347 | AGMAT | 79814 | 221648_s_at | 0.8509 | 0.0001 | |
| GSE23400 | AGMAT | 79814 | 221648_s_at | 0.3054 | 0.0000 | |
| GSE26886 | AGMAT | 79814 | 221648_s_at | 1.2691 | 0.0151 | |
| GSE29001 | AGMAT | 79814 | 221648_s_at | 1.1735 | 0.0028 | |
| GSE38129 | AGMAT | 79814 | 221648_s_at | 0.9167 | 0.0001 | |
| GSE45670 | AGMAT | 79814 | 221648_s_at | 1.3078 | 0.0000 | |
| GSE53622 | AGMAT | 79814 | 11081 | 0.7059 | 0.0002 | |
| GSE53624 | AGMAT | 79814 | 11081 | 0.9934 | 0.0000 | |
| GSE63941 | AGMAT | 79814 | 222930_s_at | -0.1296 | 0.8177 | |
| GSE77861 | AGMAT | 79814 | 219792_at | -0.0040 | 0.9794 | |
| GSE97050 | AGMAT | 79814 | A_23_P103720 | 0.7395 | 0.1453 | |
| SRP007169 | AGMAT | 79814 | RNAseq | 0.5448 | 0.3636 | |
| SRP008496 | AGMAT | 79814 | RNAseq | 0.6322 | 0.1119 | |
| SRP064894 | AGMAT | 79814 | RNAseq | 1.0664 | 0.0001 | |
| SRP133303 | AGMAT | 79814 | RNAseq | 0.2100 | 0.0944 | |
| SRP159526 | AGMAT | 79814 | RNAseq | 0.4711 | 0.3336 | |
| SRP193095 | AGMAT | 79814 | RNAseq | 0.3020 | 0.2812 | |
| SRP219564 | AGMAT | 79814 | RNAseq | -0.0095 | 0.9841 | |
| TCGA | AGMAT | 79814 | RNAseq | 0.6470 | 0.0022 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by AGMAT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AGMAT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AGMAT | 79814 | 1 | 5 | 24 | |
| GSE20123 | AGMAT | 79814 | 1 | 4 | 25 | |
| GSE43470 | AGMAT | 79814 | 1 | 8 | 34 | |
| GSE46452 | AGMAT | 79814 | 7 | 1 | 51 | |
| GSE47630 | AGMAT | 79814 | 8 | 3 | 29 | |
| GSE54993 | AGMAT | 79814 | 3 | 1 | 66 | |
| GSE54994 | AGMAT | 79814 | 10 | 4 | 39 | |
| GSE60625 | AGMAT | 79814 | 0 | 0 | 11 | |
| GSE74703 | AGMAT | 79814 | 1 | 5 | 30 | |
| GSE74704 | AGMAT | 79814 | 1 | 0 | 19 | |
| TCGA | AGMAT | 79814 | 11 | 23 | 62 |
Total number of gains: 44; Total number of losses: 54; Total Number of normals: 390.
Somatic mutations of AGMAT:
Generating mutation plots.
Highly correlated genes for AGMAT:
Showing top 20/987 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AGMAT | ALG1 | 0.809339 | 3 | 0 | 3 |
| AGMAT | LRRC58 | 0.776765 | 3 | 0 | 3 |
| AGMAT | DNPEP | 0.770429 | 3 | 0 | 3 |
| AGMAT | COX16 | 0.752014 | 3 | 0 | 3 |
| AGMAT | CDCA2 | 0.751758 | 4 | 0 | 4 |
| AGMAT | SPNS1 | 0.746621 | 3 | 0 | 3 |
| AGMAT | COPB1 | 0.734928 | 3 | 0 | 3 |
| AGMAT | UTP14A | 0.732802 | 4 | 0 | 3 |
| AGMAT | RRAS2 | 0.72912 | 4 | 0 | 4 |
| AGMAT | CMIP | 0.726856 | 4 | 0 | 3 |
| AGMAT | ZNHIT2 | 0.719263 | 4 | 0 | 4 |
| AGMAT | AGPAT5 | 0.717428 | 3 | 0 | 3 |
| AGMAT | KLHL8 | 0.714397 | 3 | 0 | 3 |
| AGMAT | ACBD6 | 0.705648 | 3 | 0 | 3 |
| AGMAT | RRM2B | 0.705549 | 3 | 0 | 3 |
| AGMAT | ZNF628 | 0.704348 | 4 | 0 | 4 |
| AGMAT | NFKBID | 0.703592 | 3 | 0 | 3 |
| AGMAT | EARS2 | 0.702577 | 4 | 0 | 3 |
| AGMAT | EPB41L5 | 0.700279 | 3 | 0 | 3 |
| AGMAT | ZNF789 | 0.700003 | 3 | 0 | 3 |
For details and further investigation, click here
