| Full name: dorsal inhibitory axon guidance protein | Alias Symbol: FLJ34999|Draxin|Neucrin | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 374946 | HGNC ID: HGNC:25054 | Ensembl Gene: ENSG00000162490 | OMIM ID: 612682 |
| Drug and gene relationship at DGIdb | |||
Expression of DRAXIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DRAXIN | 374946 | 1558368_s_at | 0.1930 | 0.6272 | |
| GSE26886 | DRAXIN | 374946 | 1558368_s_at | -0.0293 | 0.8298 | |
| GSE45670 | DRAXIN | 374946 | 1558368_s_at | 0.2644 | 0.0052 | |
| GSE53622 | DRAXIN | 374946 | 60780 | 0.3965 | 0.0000 | |
| GSE53624 | DRAXIN | 374946 | 60780 | -0.2757 | 0.0079 | |
| GSE63941 | DRAXIN | 374946 | 1558368_s_at | 0.1099 | 0.6061 | |
| GSE77861 | DRAXIN | 374946 | 1556826_s_at | -0.3406 | 0.0041 | |
| SRP007169 | DRAXIN | 374946 | RNAseq | 0.9476 | 0.1837 | |
| SRP064894 | DRAXIN | 374946 | RNAseq | 0.4738 | 0.0759 | |
| SRP133303 | DRAXIN | 374946 | RNAseq | 0.2833 | 0.0296 | |
| SRP193095 | DRAXIN | 374946 | RNAseq | 0.3134 | 0.0339 | |
| SRP219564 | DRAXIN | 374946 | RNAseq | 0.5697 | 0.2694 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DRAXIN expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of DRAXIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DRAXIN | 374946 | 0 | 5 | 25 | |
| GSE20123 | DRAXIN | 374946 | 0 | 4 | 26 | |
| GSE43470 | DRAXIN | 374946 | 5 | 5 | 33 | |
| GSE46452 | DRAXIN | 374946 | 7 | 1 | 51 | |
| GSE47630 | DRAXIN | 374946 | 8 | 4 | 28 | |
| GSE54993 | DRAXIN | 374946 | 3 | 1 | 66 | |
| GSE54994 | DRAXIN | 374946 | 11 | 4 | 38 | |
| GSE60625 | DRAXIN | 374946 | 0 | 0 | 11 | |
| GSE74703 | DRAXIN | 374946 | 4 | 3 | 29 | |
| GSE74704 | DRAXIN | 374946 | 0 | 0 | 20 | |
| TCGA | DRAXIN | 374946 | 10 | 23 | 63 |
Total number of gains: 48; Total number of losses: 50; Total Number of normals: 390.
Somatic mutations of DRAXIN:
Generating mutation plots.
Highly correlated genes for DRAXIN:
Showing top 20/69 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DRAXIN | LINC00930 | 0.680774 | 3 | 0 | 3 |
| DRAXIN | CA6 | 0.678185 | 3 | 0 | 3 |
| DRAXIN | AJAP1 | 0.663593 | 4 | 0 | 3 |
| DRAXIN | HGFAC | 0.629175 | 3 | 0 | 3 |
| DRAXIN | CCIN | 0.618239 | 3 | 0 | 3 |
| DRAXIN | FNDC9 | 0.617512 | 4 | 0 | 3 |
| DRAXIN | ADAM12 | 0.612628 | 3 | 0 | 3 |
| DRAXIN | NKX6-3 | 0.612541 | 4 | 0 | 3 |
| DRAXIN | BCKDK | 0.611275 | 3 | 0 | 3 |
| DRAXIN | HAND1 | 0.609396 | 4 | 0 | 4 |
| DRAXIN | CCDC154 | 0.606881 | 3 | 0 | 3 |
| DRAXIN | BTNL2 | 0.602888 | 4 | 0 | 3 |
| DRAXIN | FAM171A2 | 0.593086 | 3 | 0 | 3 |
| DRAXIN | ABCG4 | 0.589512 | 4 | 0 | 3 |
| DRAXIN | KCNH3 | 0.589435 | 3 | 0 | 3 |
| DRAXIN | GJD4 | 0.589243 | 4 | 0 | 3 |
| DRAXIN | SLC22A9 | 0.589039 | 3 | 0 | 3 |
| DRAXIN | ZNF843 | 0.584814 | 4 | 0 | 4 |
| DRAXIN | RTN4RL2 | 0.582731 | 4 | 0 | 3 |
| DRAXIN | ZNF32-AS3 | 0.581211 | 3 | 0 | 3 |
For details and further investigation, click here
