| Full name: adherens junctions associated protein 1 | Alias Symbol: SHREW1|SHREW-1|MOT8 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 55966 | HGNC ID: HGNC:30801 | Ensembl Gene: ENSG00000196581 | OMIM ID: 610972 |
| Drug and gene relationship at DGIdb | |||
Expression of AJAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AJAP1 | 55966 | 215789_s_at | 0.0964 | 0.8616 | |
| GSE20347 | AJAP1 | 55966 | 206460_at | 0.1715 | 0.2809 | |
| GSE23400 | AJAP1 | 55966 | 206460_at | -0.0414 | 0.3874 | |
| GSE26886 | AJAP1 | 55966 | 215789_s_at | 0.5889 | 0.0077 | |
| GSE29001 | AJAP1 | 55966 | 215789_s_at | 0.2799 | 0.4199 | |
| GSE38129 | AJAP1 | 55966 | 215789_s_at | 0.0459 | 0.6061 | |
| GSE45670 | AJAP1 | 55966 | 215789_s_at | 0.7082 | 0.1594 | |
| GSE53622 | AJAP1 | 55966 | 88504 | -0.0655 | 0.3275 | |
| GSE53624 | AJAP1 | 55966 | 88504 | -0.1114 | 0.3192 | |
| GSE63941 | AJAP1 | 55966 | 215789_s_at | 0.3051 | 0.4692 | |
| GSE77861 | AJAP1 | 55966 | 215149_at | -0.1013 | 0.2035 | |
| GSE97050 | AJAP1 | 55966 | A_23_P23155 | 1.3884 | 0.1720 | |
| SRP133303 | AJAP1 | 55966 | RNAseq | 1.7251 | 0.0013 | |
| SRP159526 | AJAP1 | 55966 | RNAseq | 2.2113 | 0.0038 | |
| SRP193095 | AJAP1 | 55966 | RNAseq | 0.4360 | 0.0534 | |
| SRP219564 | AJAP1 | 55966 | RNAseq | 2.1562 | 0.0083 | |
| TCGA | AJAP1 | 55966 | RNAseq | 1.2938 | 0.0045 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by AJAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AJAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AJAP1 | 55966 | 3 | 6 | 21 | |
| GSE20123 | AJAP1 | 55966 | 3 | 5 | 22 | |
| GSE43470 | AJAP1 | 55966 | 4 | 5 | 34 | |
| GSE46452 | AJAP1 | 55966 | 7 | 1 | 51 | |
| GSE47630 | AJAP1 | 55966 | 8 | 4 | 28 | |
| GSE54993 | AJAP1 | 55966 | 3 | 2 | 65 | |
| GSE54994 | AJAP1 | 55966 | 14 | 3 | 36 | |
| GSE60625 | AJAP1 | 55966 | 0 | 0 | 11 | |
| GSE74703 | AJAP1 | 55966 | 4 | 3 | 29 | |
| GSE74704 | AJAP1 | 55966 | 3 | 0 | 17 | |
| TCGA | AJAP1 | 55966 | 12 | 21 | 63 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of AJAP1:
Generating mutation plots.
Highly correlated genes for AJAP1:
Showing top 20/140 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AJAP1 | STON2 | 0.720008 | 3 | 0 | 3 |
| AJAP1 | TAS2R38 | 0.676246 | 4 | 0 | 3 |
| AJAP1 | UNC5CL | 0.667598 | 3 | 0 | 3 |
| AJAP1 | MAPK11 | 0.66547 | 4 | 0 | 4 |
| AJAP1 | CCNA1 | 0.664829 | 4 | 0 | 3 |
| AJAP1 | DRAXIN | 0.663593 | 4 | 0 | 3 |
| AJAP1 | MTG1 | 0.66055 | 3 | 0 | 3 |
| AJAP1 | MRTO4 | 0.660213 | 3 | 0 | 3 |
| AJAP1 | BIRC3 | 0.659703 | 3 | 0 | 3 |
| AJAP1 | BARHL1 | 0.658687 | 3 | 0 | 3 |
| AJAP1 | NAGS | 0.656063 | 4 | 0 | 3 |
| AJAP1 | NOB1 | 0.654635 | 3 | 0 | 3 |
| AJAP1 | ELAC2 | 0.651691 | 3 | 0 | 3 |
| AJAP1 | ITGA4 | 0.647704 | 3 | 0 | 3 |
| AJAP1 | ARX | 0.647048 | 3 | 0 | 3 |
| AJAP1 | ZNF778 | 0.646466 | 3 | 0 | 3 |
| AJAP1 | GALNT6 | 0.645853 | 5 | 0 | 5 |
| AJAP1 | ALPK2 | 0.642237 | 3 | 0 | 3 |
| AJAP1 | PDPN | 0.641624 | 5 | 0 | 5 |
| AJAP1 | PDE4D | 0.638034 | 3 | 0 | 3 |
For details and further investigation, click here
