| Full name: reticulon 4 receptor like 2 | Alias Symbol: NgR2|NGRH1 | ||
| Type: protein-coding gene | Cytoband: 11q12.1 | ||
| Entrez ID: 349667 | HGNC ID: HGNC:23053 | Ensembl Gene: ENSG00000186907 | OMIM ID: 610462 |
| Drug and gene relationship at DGIdb | |||
Expression of RTN4RL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RTN4RL2 | 349667 | 229345_at | -0.0123 | 0.9779 | |
| GSE26886 | RTN4RL2 | 349667 | 229345_at | 0.1344 | 0.1784 | |
| GSE45670 | RTN4RL2 | 349667 | 229345_at | 0.0691 | 0.4849 | |
| GSE53622 | RTN4RL2 | 349667 | 25566 | 0.5160 | 0.0000 | |
| GSE53624 | RTN4RL2 | 349667 | 25566 | 0.3866 | 0.0000 | |
| GSE63941 | RTN4RL2 | 349667 | 229345_at | 0.2731 | 0.3582 | |
| GSE77861 | RTN4RL2 | 349667 | 229345_at | -0.3375 | 0.0407 | |
| GSE97050 | RTN4RL2 | 349667 | A_32_P528311 | 0.4843 | 0.1623 | |
| SRP133303 | RTN4RL2 | 349667 | RNAseq | 0.5984 | 0.0935 | |
| SRP159526 | RTN4RL2 | 349667 | RNAseq | 1.8531 | 0.0002 | |
| SRP219564 | RTN4RL2 | 349667 | RNAseq | 1.5437 | 0.0053 | |
| TCGA | RTN4RL2 | 349667 | RNAseq | 0.7915 | 0.0001 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by RTN4RL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RTN4RL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RTN4RL2 | 349667 | 2 | 3 | 25 | |
| GSE20123 | RTN4RL2 | 349667 | 2 | 3 | 25 | |
| GSE43470 | RTN4RL2 | 349667 | 1 | 5 | 37 | |
| GSE46452 | RTN4RL2 | 349667 | 8 | 4 | 47 | |
| GSE47630 | RTN4RL2 | 349667 | 3 | 9 | 28 | |
| GSE54993 | RTN4RL2 | 349667 | 3 | 0 | 67 | |
| GSE54994 | RTN4RL2 | 349667 | 5 | 6 | 42 | |
| GSE60625 | RTN4RL2 | 349667 | 0 | 3 | 8 | |
| GSE74703 | RTN4RL2 | 349667 | 1 | 3 | 32 | |
| GSE74704 | RTN4RL2 | 349667 | 2 | 3 | 15 | |
| TCGA | RTN4RL2 | 349667 | 14 | 10 | 72 |
Total number of gains: 41; Total number of losses: 49; Total Number of normals: 398.
Somatic mutations of RTN4RL2:
Generating mutation plots.
Highly correlated genes for RTN4RL2:
Showing top 20/172 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RTN4RL2 | GLI4 | 0.671388 | 3 | 0 | 3 |
| RTN4RL2 | FFAR2 | 0.655577 | 3 | 0 | 3 |
| RTN4RL2 | PDZD7 | 0.655293 | 5 | 0 | 3 |
| RTN4RL2 | LHB | 0.655181 | 3 | 0 | 3 |
| RTN4RL2 | LRRC10 | 0.652384 | 3 | 0 | 3 |
| RTN4RL2 | DNAH2 | 0.642535 | 3 | 0 | 3 |
| RTN4RL2 | SLC6A3 | 0.641546 | 4 | 0 | 3 |
| RTN4RL2 | MS4A18 | 0.64037 | 3 | 0 | 3 |
| RTN4RL2 | DEFB121 | 0.640113 | 5 | 0 | 5 |
| RTN4RL2 | NKX6-3 | 0.639539 | 4 | 0 | 3 |
| RTN4RL2 | TP73 | 0.638228 | 6 | 0 | 6 |
| RTN4RL2 | LIPE-AS1 | 0.631642 | 3 | 0 | 3 |
| RTN4RL2 | DPF1 | 0.628157 | 4 | 0 | 3 |
| RTN4RL2 | ELOVL3 | 0.623312 | 3 | 0 | 3 |
| RTN4RL2 | CYP4F22 | 0.62314 | 3 | 0 | 3 |
| RTN4RL2 | HAGHL | 0.622182 | 5 | 0 | 4 |
| RTN4RL2 | LINC00858 | 0.619288 | 3 | 0 | 3 |
| RTN4RL2 | TSPO2 | 0.618736 | 3 | 0 | 3 |
| RTN4RL2 | OTP | 0.61651 | 3 | 0 | 3 |
| RTN4RL2 | MC1R | 0.61523 | 3 | 0 | 3 |
For details and further investigation, click here
