| Full name: ATP binding cassette subfamily G member 4 | Alias Symbol: WHITE2 | ||
| Type: protein-coding gene | Cytoband: 11q23.3 | ||
| Entrez ID: 64137 | HGNC ID: HGNC:13884 | Ensembl Gene: ENSG00000172350 | OMIM ID: 607784 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCG4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCG4 | 64137 | 207593_at | -0.0846 | 0.7812 | |
| GSE20347 | ABCG4 | 64137 | 207593_at | -0.1529 | 0.0450 | |
| GSE23400 | ABCG4 | 64137 | 207593_at | -0.2388 | 0.0000 | |
| GSE26886 | ABCG4 | 64137 | 207593_at | -0.2198 | 0.0693 | |
| GSE29001 | ABCG4 | 64137 | 207593_at | -0.3636 | 0.0498 | |
| GSE38129 | ABCG4 | 64137 | 207593_at | -0.3139 | 0.0090 | |
| GSE45670 | ABCG4 | 64137 | 207593_at | 0.1073 | 0.2965 | |
| GSE53622 | ABCG4 | 64137 | 57453 | -0.5561 | 0.0000 | |
| GSE53624 | ABCG4 | 64137 | 57453 | -0.3920 | 0.0000 | |
| GSE63941 | ABCG4 | 64137 | 207593_at | -0.0328 | 0.8586 | |
| GSE77861 | ABCG4 | 64137 | 207593_at | -0.1949 | 0.0548 | |
| SRP064894 | ABCG4 | 64137 | RNAseq | -1.5214 | 0.0000 | |
| SRP159526 | ABCG4 | 64137 | RNAseq | -1.1886 | 0.0853 | |
| SRP219564 | ABCG4 | 64137 | RNAseq | -2.6642 | 0.0000 | |
| TCGA | ABCG4 | 64137 | RNAseq | -0.2830 | 0.4363 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ABCG4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCG4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCG4 | 64137 | 1 | 11 | 18 | |
| GSE20123 | ABCG4 | 64137 | 1 | 11 | 18 | |
| GSE43470 | ABCG4 | 64137 | 2 | 8 | 33 | |
| GSE46452 | ABCG4 | 64137 | 3 | 26 | 30 | |
| GSE47630 | ABCG4 | 64137 | 2 | 19 | 19 | |
| GSE54993 | ABCG4 | 64137 | 10 | 0 | 60 | |
| GSE54994 | ABCG4 | 64137 | 5 | 19 | 29 | |
| GSE60625 | ABCG4 | 64137 | 0 | 3 | 8 | |
| GSE74703 | ABCG4 | 64137 | 1 | 5 | 30 | |
| GSE74704 | ABCG4 | 64137 | 0 | 7 | 13 | |
| TCGA | ABCG4 | 64137 | 4 | 51 | 41 |
Total number of gains: 29; Total number of losses: 160; Total Number of normals: 299.
Somatic mutations of ABCG4:
Generating mutation plots.
Highly correlated genes for ABCG4:
Showing top 20/1134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCG4 | GJA3 | 0.758699 | 4 | 0 | 4 |
| ABCG4 | RAB3IL1 | 0.716995 | 3 | 0 | 3 |
| ABCG4 | PSG5 | 0.700016 | 5 | 0 | 4 |
| ABCG4 | EPOR | 0.698766 | 6 | 0 | 6 |
| ABCG4 | TSSK2 | 0.693346 | 6 | 0 | 6 |
| ABCG4 | TCL6 | 0.681411 | 5 | 0 | 5 |
| ABCG4 | ATN1 | 0.67833 | 3 | 0 | 3 |
| ABCG4 | PHLDB1 | 0.676058 | 5 | 0 | 4 |
| ABCG4 | IFNA21 | 0.67602 | 4 | 0 | 4 |
| ABCG4 | OTOR | 0.675707 | 7 | 0 | 6 |
| ABCG4 | ART1 | 0.673421 | 5 | 0 | 5 |
| ABCG4 | SNX33 | 0.672809 | 3 | 0 | 3 |
| ABCG4 | CYP3A43 | 0.671434 | 6 | 0 | 5 |
| ABCG4 | KCNV1 | 0.669853 | 3 | 0 | 3 |
| ABCG4 | IGH | 0.669329 | 5 | 0 | 5 |
| ABCG4 | PNLIPRP1 | 0.663867 | 5 | 0 | 5 |
| ABCG4 | TPSD1 | 0.663608 | 6 | 0 | 6 |
| ABCG4 | GJC2 | 0.662734 | 6 | 0 | 5 |
| ABCG4 | REEP2 | 0.661036 | 6 | 0 | 6 |
| ABCG4 | ADAM11 | 0.65893 | 8 | 0 | 6 |
For details and further investigation, click here
