| Full name: dual specificity phosphatase 19 | Alias Symbol: SKRP1|DUSP17 | ||
| Type: protein-coding gene | Cytoband: 2q32.1 | ||
| Entrez ID: 142679 | HGNC ID: HGNC:18894 | Ensembl Gene: ENSG00000162999 | OMIM ID: 611437 |
| Drug and gene relationship at DGIdb | |||
Expression of DUSP19:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUSP19 | 142679 | 1552705_at | 0.0927 | 0.8273 | |
| GSE26886 | DUSP19 | 142679 | 1555598_a_at | 0.0034 | 0.9797 | |
| GSE45670 | DUSP19 | 142679 | 1552705_at | -0.3390 | 0.2052 | |
| GSE53622 | DUSP19 | 142679 | 63727 | -0.4217 | 0.0032 | |
| GSE53624 | DUSP19 | 142679 | 63727 | -0.1395 | 0.3248 | |
| GSE63941 | DUSP19 | 142679 | 1555598_a_at | 0.4463 | 0.3646 | |
| GSE77861 | DUSP19 | 142679 | 1555598_a_at | -0.1187 | 0.2267 | |
| GSE97050 | DUSP19 | 142679 | A_23_P90933 | -0.6811 | 0.1594 | |
| SRP007169 | DUSP19 | 142679 | RNAseq | 0.6492 | 0.1595 | |
| SRP008496 | DUSP19 | 142679 | RNAseq | 1.0984 | 0.0018 | |
| SRP064894 | DUSP19 | 142679 | RNAseq | -0.2913 | 0.2014 | |
| SRP133303 | DUSP19 | 142679 | RNAseq | -0.1467 | 0.3932 | |
| SRP159526 | DUSP19 | 142679 | RNAseq | -0.0782 | 0.8138 | |
| SRP193095 | DUSP19 | 142679 | RNAseq | -0.2480 | 0.1641 | |
| SRP219564 | DUSP19 | 142679 | RNAseq | -0.5572 | 0.2899 | |
| TCGA | DUSP19 | 142679 | RNAseq | -0.8874 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DUSP19 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUSP19:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUSP19 | 142679 | 5 | 2 | 23 | |
| GSE20123 | DUSP19 | 142679 | 5 | 2 | 23 | |
| GSE43470 | DUSP19 | 142679 | 5 | 1 | 37 | |
| GSE46452 | DUSP19 | 142679 | 1 | 4 | 54 | |
| GSE47630 | DUSP19 | 142679 | 4 | 4 | 32 | |
| GSE54993 | DUSP19 | 142679 | 0 | 5 | 65 | |
| GSE54994 | DUSP19 | 142679 | 12 | 5 | 36 | |
| GSE60625 | DUSP19 | 142679 | 0 | 3 | 8 | |
| GSE74703 | DUSP19 | 142679 | 4 | 1 | 31 | |
| GSE74704 | DUSP19 | 142679 | 2 | 2 | 16 | |
| TCGA | DUSP19 | 142679 | 27 | 8 | 61 |
Total number of gains: 65; Total number of losses: 37; Total Number of normals: 386.
Somatic mutations of DUSP19:
Generating mutation plots.
Highly correlated genes for DUSP19:
Showing top 20/109 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUSP19 | NDUFA10 | 0.816451 | 3 | 0 | 3 |
| DUSP19 | NES | 0.766152 | 3 | 0 | 3 |
| DUSP19 | SNX1 | 0.736611 | 3 | 0 | 3 |
| DUSP19 | ZNF626 | 0.730573 | 3 | 0 | 3 |
| DUSP19 | SLC30A5 | 0.722892 | 3 | 0 | 3 |
| DUSP19 | CKMT2 | 0.715028 | 3 | 0 | 3 |
| DUSP19 | ADH5 | 0.713698 | 3 | 0 | 3 |
| DUSP19 | ZNF641 | 0.709252 | 3 | 0 | 3 |
| DUSP19 | DCTN4 | 0.706968 | 3 | 0 | 3 |
| DUSP19 | PPP3CB | 0.704703 | 3 | 0 | 3 |
| DUSP19 | MAT2B | 0.701397 | 3 | 0 | 3 |
| DUSP19 | AVPR1A | 0.695488 | 3 | 0 | 3 |
| DUSP19 | SYNJ2BP | 0.691922 | 4 | 0 | 4 |
| DUSP19 | SYAP1 | 0.688228 | 4 | 0 | 3 |
| DUSP19 | RMND5B | 0.688142 | 3 | 0 | 3 |
| DUSP19 | KCTD7 | 0.686728 | 4 | 0 | 4 |
| DUSP19 | PLEKHB2 | 0.683121 | 4 | 0 | 4 |
| DUSP19 | TRAPPC2L | 0.682618 | 4 | 0 | 3 |
| DUSP19 | ANKRD50 | 0.680367 | 3 | 0 | 3 |
| DUSP19 | TMEM19 | 0.675925 | 3 | 0 | 3 |
For details and further investigation, click here
