| Full name: sorting nexin 1 | Alias Symbol: SNX1A|MGC8664|HsT17379|Vps5 | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 6642 | HGNC ID: HGNC:11172 | Ensembl Gene: ENSG00000028528 | OMIM ID: 601272 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX1 | 6642 | 201716_at | -0.3600 | 0.4025 | |
| GSE20347 | SNX1 | 6642 | 201716_at | -0.3842 | 0.0027 | |
| GSE23400 | SNX1 | 6642 | 201716_at | -0.3392 | 0.0000 | |
| GSE26886 | SNX1 | 6642 | 201716_at | -1.0279 | 0.0003 | |
| GSE29001 | SNX1 | 6642 | 201716_at | -0.4464 | 0.0104 | |
| GSE38129 | SNX1 | 6642 | 201716_at | -0.2106 | 0.0697 | |
| GSE45670 | SNX1 | 6642 | 201716_at | -0.2027 | 0.2020 | |
| GSE53622 | SNX1 | 6642 | 133050 | -0.9357 | 0.0000 | |
| GSE53624 | SNX1 | 6642 | 133050 | -0.8637 | 0.0000 | |
| GSE63941 | SNX1 | 6642 | 201716_at | 0.2404 | 0.5259 | |
| GSE77861 | SNX1 | 6642 | 201716_at | -0.4479 | 0.0794 | |
| GSE97050 | SNX1 | 6642 | A_33_P3268716 | -1.1535 | 0.0846 | |
| SRP007169 | SNX1 | 6642 | RNAseq | -0.8942 | 0.0057 | |
| SRP008496 | SNX1 | 6642 | RNAseq | -0.8511 | 0.0000 | |
| SRP064894 | SNX1 | 6642 | RNAseq | -0.4747 | 0.0004 | |
| SRP133303 | SNX1 | 6642 | RNAseq | -0.4430 | 0.0000 | |
| SRP159526 | SNX1 | 6642 | RNAseq | -0.6211 | 0.0008 | |
| SRP193095 | SNX1 | 6642 | RNAseq | -0.2102 | 0.0186 | |
| SRP219564 | SNX1 | 6642 | RNAseq | -0.5984 | 0.0253 | |
| TCGA | SNX1 | 6642 | RNAseq | -0.2199 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SNX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX1 | 6642 | 7 | 3 | 20 | |
| GSE20123 | SNX1 | 6642 | 7 | 3 | 20 | |
| GSE43470 | SNX1 | 6642 | 4 | 6 | 33 | |
| GSE46452 | SNX1 | 6642 | 3 | 7 | 49 | |
| GSE47630 | SNX1 | 6642 | 8 | 10 | 22 | |
| GSE54993 | SNX1 | 6642 | 5 | 6 | 59 | |
| GSE54994 | SNX1 | 6642 | 6 | 8 | 39 | |
| GSE60625 | SNX1 | 6642 | 4 | 0 | 7 | |
| GSE74703 | SNX1 | 6642 | 4 | 3 | 29 | |
| GSE74704 | SNX1 | 6642 | 3 | 3 | 14 | |
| TCGA | SNX1 | 6642 | 10 | 17 | 69 |
Total number of gains: 61; Total number of losses: 66; Total Number of normals: 361.
Somatic mutations of SNX1:
Generating mutation plots.
Highly correlated genes for SNX1:
Showing top 20/1217 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX1 | XKR4 | 0.795608 | 3 | 0 | 3 |
| SNX1 | LDB3 | 0.790528 | 4 | 0 | 4 |
| SNX1 | CLEC3B | 0.778528 | 3 | 0 | 3 |
| SNX1 | ANO5 | 0.772647 | 3 | 0 | 3 |
| SNX1 | C1QTNF7 | 0.769329 | 4 | 0 | 4 |
| SNX1 | CFL2 | 0.768491 | 3 | 0 | 3 |
| SNX1 | SMYD1 | 0.761186 | 3 | 0 | 3 |
| SNX1 | ZMAT1 | 0.752446 | 3 | 0 | 3 |
| SNX1 | CYP21A2 | 0.749744 | 3 | 0 | 3 |
| SNX1 | NEGR1 | 0.749551 | 3 | 0 | 3 |
| SNX1 | CPEB2 | 0.739587 | 3 | 0 | 3 |
| SNX1 | DUSP19 | 0.736611 | 3 | 0 | 3 |
| SNX1 | ECI2 | 0.73519 | 3 | 0 | 3 |
| SNX1 | TMEM170B | 0.734508 | 3 | 0 | 3 |
| SNX1 | PDK2 | 0.731081 | 3 | 0 | 3 |
| SNX1 | KLHDC9 | 0.729737 | 3 | 0 | 3 |
| SNX1 | MKRN1 | 0.717944 | 3 | 0 | 3 |
| SNX1 | ROBO4 | 0.717719 | 4 | 0 | 3 |
| SNX1 | IL33 | 0.714906 | 4 | 0 | 4 |
| SNX1 | MEF2C-AS1 | 0.713704 | 4 | 0 | 4 |
For details and further investigation, click here
