| Full name: pleckstrin homology domain containing B2 | Alias Symbol: EVT2|FLJ20783 | ||
| Type: protein-coding gene | Cytoband: 2q21.1 | ||
| Entrez ID: 55041 | HGNC ID: HGNC:19236 | Ensembl Gene: ENSG00000115762 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PLEKHB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PLEKHB2 | 55041 | 201410_at | 0.6076 | 0.0596 | |
| GSE20347 | PLEKHB2 | 55041 | 201410_at | 0.2121 | 0.0640 | |
| GSE23400 | PLEKHB2 | 55041 | 201410_at | 0.3010 | 0.0000 | |
| GSE26886 | PLEKHB2 | 55041 | 201410_at | 0.0542 | 0.7646 | |
| GSE29001 | PLEKHB2 | 55041 | 201410_at | 0.1991 | 0.5104 | |
| GSE38129 | PLEKHB2 | 55041 | 201410_at | 0.3275 | 0.0007 | |
| GSE45670 | PLEKHB2 | 55041 | 201410_at | 0.1964 | 0.0908 | |
| GSE53622 | PLEKHB2 | 55041 | 57667 | 0.2246 | 0.0013 | |
| GSE53624 | PLEKHB2 | 55041 | 57667 | 0.2402 | 0.0019 | |
| GSE63941 | PLEKHB2 | 55041 | 201410_at | -0.3031 | 0.4991 | |
| GSE77861 | PLEKHB2 | 55041 | 201410_at | 0.3096 | 0.2936 | |
| GSE97050 | PLEKHB2 | 55041 | A_24_P873414 | 0.3189 | 0.2763 | |
| SRP007169 | PLEKHB2 | 55041 | RNAseq | 0.2483 | 0.5877 | |
| SRP008496 | PLEKHB2 | 55041 | RNAseq | 0.5381 | 0.0434 | |
| SRP064894 | PLEKHB2 | 55041 | RNAseq | 0.0368 | 0.8356 | |
| SRP133303 | PLEKHB2 | 55041 | RNAseq | 0.3817 | 0.0126 | |
| SRP159526 | PLEKHB2 | 55041 | RNAseq | 0.1562 | 0.6130 | |
| SRP193095 | PLEKHB2 | 55041 | RNAseq | -0.2739 | 0.0887 | |
| SRP219564 | PLEKHB2 | 55041 | RNAseq | -0.1256 | 0.7051 | |
| TCGA | PLEKHB2 | 55041 | RNAseq | -0.1976 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PLEKHB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PLEKHB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PLEKHB2 | 55041 | 4 | 3 | 23 | |
| GSE20123 | PLEKHB2 | 55041 | 4 | 3 | 23 | |
| GSE43470 | PLEKHB2 | 55041 | 2 | 2 | 39 | |
| GSE46452 | PLEKHB2 | 55041 | 1 | 3 | 55 | |
| GSE47630 | PLEKHB2 | 55041 | 5 | 0 | 35 | |
| GSE54993 | PLEKHB2 | 55041 | 0 | 6 | 64 | |
| GSE54994 | PLEKHB2 | 55041 | 10 | 0 | 43 | |
| GSE60625 | PLEKHB2 | 55041 | 0 | 3 | 8 | |
| GSE74703 | PLEKHB2 | 55041 | 2 | 1 | 33 | |
| GSE74704 | PLEKHB2 | 55041 | 2 | 1 | 17 | |
| TCGA | PLEKHB2 | 55041 | 22 | 10 | 64 |
Total number of gains: 52; Total number of losses: 32; Total Number of normals: 404.
Somatic mutations of PLEKHB2:
Generating mutation plots.
Highly correlated genes for PLEKHB2:
Showing top 20/597 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PLEKHB2 | CDC27 | 0.79494 | 3 | 0 | 3 |
| PLEKHB2 | ARL13B | 0.763918 | 4 | 0 | 4 |
| PLEKHB2 | THOC5 | 0.762916 | 3 | 0 | 3 |
| PLEKHB2 | ZC3H7B | 0.748679 | 3 | 0 | 3 |
| PLEKHB2 | TGFBR1 | 0.747661 | 3 | 0 | 3 |
| PLEKHB2 | KIF3A | 0.738206 | 3 | 0 | 3 |
| PLEKHB2 | SLC39A1 | 0.735557 | 3 | 0 | 3 |
| PLEKHB2 | BRAP | 0.734033 | 3 | 0 | 3 |
| PLEKHB2 | FLNB | 0.72648 | 3 | 0 | 3 |
| PLEKHB2 | FHOD1 | 0.723084 | 3 | 0 | 3 |
| PLEKHB2 | MRPS5 | 0.720804 | 3 | 0 | 3 |
| PLEKHB2 | USP37 | 0.715697 | 3 | 0 | 3 |
| PLEKHB2 | ANKRD50 | 0.714746 | 4 | 0 | 3 |
| PLEKHB2 | ARFGEF2 | 0.71393 | 3 | 0 | 3 |
| PLEKHB2 | NBAS | 0.713568 | 3 | 0 | 3 |
| PLEKHB2 | MRPS22 | 0.713408 | 3 | 0 | 3 |
| PLEKHB2 | PDE8A | 0.713257 | 4 | 0 | 3 |
| PLEKHB2 | UEVLD | 0.712696 | 3 | 0 | 3 |
| PLEKHB2 | MGAT4B | 0.712543 | 3 | 0 | 3 |
| PLEKHB2 | IMMP1L | 0.712289 | 3 | 0 | 3 |
For details and further investigation, click here
