| Full name: EBF transcription factor 2 | Alias Symbol: FLJ11500|COE2 | ||
| Type: protein-coding gene | Cytoband: 8p21.2 | ||
| Entrez ID: 64641 | HGNC ID: HGNC:19090 | Ensembl Gene: ENSG00000221818 | OMIM ID: 609934 |
| Drug and gene relationship at DGIdb | |||
Expression of EBF2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EBF2 | 64641 | 220392_at | -0.3599 | 0.3529 | |
| GSE20347 | EBF2 | 64641 | 220392_at | -0.0133 | 0.9015 | |
| GSE23400 | EBF2 | 64641 | 220392_at | -0.1506 | 0.0000 | |
| GSE26886 | EBF2 | 64641 | 220392_at | -0.1005 | 0.3230 | |
| GSE29001 | EBF2 | 64641 | 220392_at | 0.0129 | 0.9391 | |
| GSE38129 | EBF2 | 64641 | 220392_at | -0.2730 | 0.0393 | |
| GSE45670 | EBF2 | 64641 | 244885_at | -1.1939 | 0.0003 | |
| GSE53622 | EBF2 | 64641 | 15936 | 0.0957 | 0.5735 | |
| GSE53624 | EBF2 | 64641 | 15936 | 0.2509 | 0.1163 | |
| GSE63941 | EBF2 | 64641 | 1562477_at | -0.1010 | 0.3870 | |
| GSE77861 | EBF2 | 64641 | 220392_at | -0.1450 | 0.1861 | |
| GSE97050 | EBF2 | 64641 | A_24_P43826 | -0.1946 | 0.5858 | |
| SRP133303 | EBF2 | 64641 | RNAseq | -0.0688 | 0.8762 | |
| SRP159526 | EBF2 | 64641 | RNAseq | -0.8957 | 0.0744 | |
| SRP219564 | EBF2 | 64641 | RNAseq | 0.5024 | 0.5801 | |
| TCGA | EBF2 | 64641 | RNAseq | -0.9328 | 0.0566 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EBF2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EBF2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EBF2 | 64641 | 4 | 12 | 14 | |
| GSE20123 | EBF2 | 64641 | 4 | 12 | 14 | |
| GSE43470 | EBF2 | 64641 | 4 | 7 | 32 | |
| GSE46452 | EBF2 | 64641 | 13 | 13 | 33 | |
| GSE47630 | EBF2 | 64641 | 10 | 8 | 22 | |
| GSE54993 | EBF2 | 64641 | 2 | 15 | 53 | |
| GSE54994 | EBF2 | 64641 | 9 | 16 | 28 | |
| GSE60625 | EBF2 | 64641 | 3 | 0 | 8 | |
| GSE74703 | EBF2 | 64641 | 4 | 6 | 26 | |
| GSE74704 | EBF2 | 64641 | 3 | 8 | 9 | |
| TCGA | EBF2 | 64641 | 15 | 44 | 37 |
Total number of gains: 71; Total number of losses: 141; Total Number of normals: 276.
Somatic mutations of EBF2:
Generating mutation plots.
Highly correlated genes for EBF2:
Showing top 20/518 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EBF2 | XKR4 | 0.813596 | 3 | 0 | 3 |
| EBF2 | KLF11 | 0.782433 | 3 | 0 | 3 |
| EBF2 | SPEG | 0.773301 | 3 | 0 | 3 |
| EBF2 | KCNK2 | 0.766512 | 4 | 0 | 4 |
| EBF2 | ZBTB10 | 0.757249 | 3 | 0 | 3 |
| EBF2 | HTR2B | 0.751022 | 3 | 0 | 3 |
| EBF2 | OR2T33 | 0.745592 | 3 | 0 | 3 |
| EBF2 | KRTAP10-9 | 0.734393 | 3 | 0 | 3 |
| EBF2 | KAT7 | 0.731685 | 3 | 0 | 3 |
| EBF2 | STARD13 | 0.73019 | 4 | 0 | 3 |
| EBF2 | CCDC30 | 0.724394 | 3 | 0 | 3 |
| EBF2 | MRPL41 | 0.721729 | 3 | 0 | 3 |
| EBF2 | ANGPTL1 | 0.718417 | 4 | 0 | 4 |
| EBF2 | PCBP3 | 0.717687 | 3 | 0 | 3 |
| EBF2 | GALR1 | 0.713229 | 3 | 0 | 3 |
| EBF2 | CACNA2D2 | 0.712725 | 4 | 0 | 4 |
| EBF2 | RNF146 | 0.711359 | 4 | 0 | 4 |
| EBF2 | GPIHBP1 | 0.710403 | 4 | 0 | 4 |
| EBF2 | VEZF1 | 0.70704 | 3 | 0 | 3 |
| EBF2 | BTN2A2 | 0.70637 | 3 | 0 | 3 |
For details and further investigation, click here
