| Full name: Kruppel like factor 11 | Alias Symbol: Tieg3|MODY7 | ||
| Type: protein-coding gene | Cytoband: 2p25.1 | ||
| Entrez ID: 8462 | HGNC ID: HGNC:11811 | Ensembl Gene: ENSG00000172059 | OMIM ID: 603301 |
| Drug and gene relationship at DGIdb | |||
Expression of KLF11:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF11 | 8462 | 218486_at | -0.2581 | 0.7146 | |
| GSE20347 | KLF11 | 8462 | 218486_at | 0.5525 | 0.0123 | |
| GSE23400 | KLF11 | 8462 | 218486_at | 0.0167 | 0.8614 | |
| GSE26886 | KLF11 | 8462 | 218486_at | 0.7892 | 0.0063 | |
| GSE29001 | KLF11 | 8462 | 218486_at | 0.4087 | 0.1799 | |
| GSE38129 | KLF11 | 8462 | 218486_at | 0.2344 | 0.3759 | |
| GSE45670 | KLF11 | 8462 | 218486_at | -0.6649 | 0.0005 | |
| GSE53622 | KLF11 | 8462 | 70117 | -0.0163 | 0.8985 | |
| GSE53624 | KLF11 | 8462 | 70117 | 0.0289 | 0.7546 | |
| GSE63941 | KLF11 | 8462 | 218486_at | -0.6173 | 0.4302 | |
| GSE77861 | KLF11 | 8462 | 218486_at | 0.6166 | 0.0188 | |
| GSE97050 | KLF11 | 8462 | A_23_P44505 | -0.6256 | 0.1733 | |
| SRP007169 | KLF11 | 8462 | RNAseq | 0.4493 | 0.2452 | |
| SRP008496 | KLF11 | 8462 | RNAseq | 0.6355 | 0.0454 | |
| SRP064894 | KLF11 | 8462 | RNAseq | 0.1836 | 0.3230 | |
| SRP133303 | KLF11 | 8462 | RNAseq | 0.3175 | 0.0303 | |
| SRP159526 | KLF11 | 8462 | RNAseq | 0.7074 | 0.0859 | |
| SRP193095 | KLF11 | 8462 | RNAseq | 0.7185 | 0.0000 | |
| SRP219564 | KLF11 | 8462 | RNAseq | -0.3009 | 0.4990 | |
| TCGA | KLF11 | 8462 | RNAseq | -0.1581 | 0.0185 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLF11 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF11:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF11 | 8462 | 11 | 2 | 17 | |
| GSE20123 | KLF11 | 8462 | 11 | 2 | 17 | |
| GSE43470 | KLF11 | 8462 | 4 | 1 | 38 | |
| GSE46452 | KLF11 | 8462 | 3 | 4 | 52 | |
| GSE47630 | KLF11 | 8462 | 7 | 0 | 33 | |
| GSE54993 | KLF11 | 8462 | 0 | 7 | 63 | |
| GSE54994 | KLF11 | 8462 | 11 | 0 | 42 | |
| GSE60625 | KLF11 | 8462 | 0 | 3 | 8 | |
| GSE74703 | KLF11 | 8462 | 3 | 0 | 33 | |
| GSE74704 | KLF11 | 8462 | 9 | 1 | 10 | |
| TCGA | KLF11 | 8462 | 34 | 5 | 57 |
Total number of gains: 93; Total number of losses: 25; Total Number of normals: 370.
Somatic mutations of KLF11:
Generating mutation plots.
Highly correlated genes for KLF11:
Showing top 20/1024 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF11 | LRRN4CL | 0.793693 | 3 | 0 | 3 |
| KLF11 | LIN7A | 0.789706 | 3 | 0 | 3 |
| KLF11 | LIX1L | 0.785693 | 4 | 0 | 4 |
| KLF11 | EPDR1 | 0.782794 | 3 | 0 | 3 |
| KLF11 | EBF2 | 0.782433 | 3 | 0 | 3 |
| KLF11 | MYCT1 | 0.781204 | 3 | 0 | 3 |
| KLF11 | PLIN4 | 0.772487 | 3 | 0 | 3 |
| KLF11 | CERS5 | 0.766258 | 3 | 0 | 3 |
| KLF11 | WWTR1 | 0.758408 | 4 | 0 | 4 |
| KLF11 | RSPO3 | 0.754827 | 3 | 0 | 3 |
| KLF11 | ANGPTL1 | 0.754122 | 3 | 0 | 3 |
| KLF11 | RAD23A | 0.753455 | 3 | 0 | 3 |
| KLF11 | XKR4 | 0.75045 | 3 | 0 | 3 |
| KLF11 | NAF1 | 0.748702 | 3 | 0 | 3 |
| KLF11 | C3orf70 | 0.748083 | 3 | 0 | 3 |
| KLF11 | RNF138 | 0.744495 | 3 | 0 | 3 |
| KLF11 | RBM18 | 0.738503 | 3 | 0 | 3 |
| KLF11 | STARD9 | 0.736468 | 3 | 0 | 3 |
| KLF11 | RGS9 | 0.735116 | 3 | 0 | 3 |
| KLF11 | PTPRB | 0.734251 | 3 | 0 | 3 |
For details and further investigation, click here
