| Full name: vascular endothelial zinc finger 1 | Alias Symbol: DB1 | ||
| Type: protein-coding gene | Cytoband: 17q22 | ||
| Entrez ID: 7716 | HGNC ID: HGNC:12949 | Ensembl Gene: ENSG00000136451 | OMIM ID: 606747 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of VEZF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VEZF1 | 7716 | 202173_s_at | -0.3588 | 0.5837 | |
| GSE20347 | VEZF1 | 7716 | 202173_s_at | 0.2698 | 0.0692 | |
| GSE23400 | VEZF1 | 7716 | 202172_at | -0.1287 | 0.2411 | |
| GSE26886 | VEZF1 | 7716 | 202172_at | 0.7445 | 0.0033 | |
| GSE29001 | VEZF1 | 7716 | 202173_s_at | 0.4019 | 0.1821 | |
| GSE38129 | VEZF1 | 7716 | 202171_at | 0.2369 | 0.2066 | |
| GSE45670 | VEZF1 | 7716 | 202172_at | -0.6477 | 0.0030 | |
| GSE53622 | VEZF1 | 7716 | 175935 | -0.6232 | 0.0000 | |
| GSE53624 | VEZF1 | 7716 | 175935 | -0.3881 | 0.0000 | |
| GSE63941 | VEZF1 | 7716 | 202171_at | -0.9314 | 0.0113 | |
| GSE77861 | VEZF1 | 7716 | 202173_s_at | 0.6154 | 0.1501 | |
| GSE97050 | VEZF1 | A_21_P0012473 | -0.1277 | 0.7378 | ||
| SRP007169 | VEZF1 | 7716 | RNAseq | 0.7568 | 0.0319 | |
| SRP008496 | VEZF1 | 7716 | RNAseq | 1.1225 | 0.0000 | |
| SRP064894 | VEZF1 | 7716 | RNAseq | -0.0629 | 0.6695 | |
| SRP133303 | VEZF1 | 7716 | RNAseq | 0.2912 | 0.0569 | |
| SRP159526 | VEZF1 | 7716 | RNAseq | 0.1506 | 0.4965 | |
| SRP193095 | VEZF1 | 7716 | RNAseq | 0.1605 | 0.0279 | |
| SRP219564 | VEZF1 | 7716 | RNAseq | 0.1160 | 0.7422 | |
| TCGA | VEZF1 | 7716 | RNAseq | -0.1234 | 0.0230 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by VEZF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VEZF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VEZF1 | 7716 | 5 | 1 | 24 | |
| GSE20123 | VEZF1 | 7716 | 5 | 1 | 24 | |
| GSE43470 | VEZF1 | 7716 | 3 | 0 | 40 | |
| GSE46452 | VEZF1 | 7716 | 32 | 0 | 27 | |
| GSE47630 | VEZF1 | 7716 | 7 | 1 | 32 | |
| GSE54993 | VEZF1 | 7716 | 2 | 5 | 63 | |
| GSE54994 | VEZF1 | 7716 | 8 | 6 | 39 | |
| GSE60625 | VEZF1 | 7716 | 4 | 0 | 7 | |
| GSE74703 | VEZF1 | 7716 | 3 | 0 | 33 | |
| GSE74704 | VEZF1 | 7716 | 4 | 1 | 15 | |
| TCGA | VEZF1 | 7716 | 26 | 8 | 62 |
Total number of gains: 99; Total number of losses: 23; Total Number of normals: 366.
Somatic mutations of VEZF1:
Generating mutation plots.
Highly correlated genes for VEZF1:
Showing top 20/1158 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VEZF1 | ZBTB26 | 0.784721 | 4 | 0 | 4 |
| VEZF1 | WDR48 | 0.784009 | 3 | 0 | 3 |
| VEZF1 | ZSCAN21 | 0.767765 | 3 | 0 | 3 |
| VEZF1 | FNIP2 | 0.755594 | 4 | 0 | 4 |
| VEZF1 | TNFSF12 | 0.752928 | 3 | 0 | 3 |
| VEZF1 | HLTF | 0.751325 | 6 | 0 | 6 |
| VEZF1 | SLC37A3 | 0.718773 | 4 | 0 | 4 |
| VEZF1 | IFT80 | 0.71766 | 3 | 0 | 3 |
| VEZF1 | NEDD1 | 0.717638 | 3 | 0 | 3 |
| VEZF1 | MRVI1 | 0.717535 | 6 | 0 | 6 |
| VEZF1 | THAP5 | 0.715744 | 3 | 0 | 3 |
| VEZF1 | GPRASP2 | 0.715707 | 3 | 0 | 3 |
| VEZF1 | NOC3L | 0.711548 | 3 | 0 | 3 |
| VEZF1 | CYP2U1 | 0.710841 | 7 | 0 | 7 |
| VEZF1 | EBF2 | 0.70704 | 3 | 0 | 3 |
| VEZF1 | MRPL9 | 0.706032 | 3 | 0 | 3 |
| VEZF1 | EIF3G | 0.706027 | 4 | 0 | 3 |
| VEZF1 | CHIC1 | 0.705292 | 4 | 0 | 3 |
| VEZF1 | TSHZ1 | 0.703968 | 5 | 0 | 5 |
| VEZF1 | SORCS1 | 0.702875 | 4 | 0 | 4 |
For details and further investigation, click here
