| Full name: enoyl-CoA hydratase domain containing 3 | Alias Symbol: FLJ20909 | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 79746 | HGNC ID: HGNC:23489 | Ensembl Gene: ENSG00000134463 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ECHDC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ECHDC3 | 79746 | 219298_at | -0.2908 | 0.8556 | |
| GSE20347 | ECHDC3 | 79746 | 219298_at | -0.2444 | 0.5740 | |
| GSE23400 | ECHDC3 | 79746 | 219298_at | -0.5376 | 0.0000 | |
| GSE26886 | ECHDC3 | 79746 | 219298_at | -0.5622 | 0.4982 | |
| GSE29001 | ECHDC3 | 79746 | 219298_at | -0.7997 | 0.0757 | |
| GSE38129 | ECHDC3 | 79746 | 219298_at | -0.4816 | 0.2121 | |
| GSE45670 | ECHDC3 | 79746 | 219298_at | -1.1932 | 0.0295 | |
| GSE53622 | ECHDC3 | 79746 | 71017 | -1.9731 | 0.0000 | |
| GSE53624 | ECHDC3 | 79746 | 71017 | -2.1783 | 0.0000 | |
| GSE63941 | ECHDC3 | 79746 | 219298_at | -0.2414 | 0.8424 | |
| GSE77861 | ECHDC3 | 79746 | 219298_at | -1.1727 | 0.0316 | |
| GSE97050 | ECHDC3 | 79746 | A_24_P343621 | -0.4899 | 0.4809 | |
| SRP064894 | ECHDC3 | 79746 | RNAseq | -1.5575 | 0.0010 | |
| SRP133303 | ECHDC3 | 79746 | RNAseq | -1.0781 | 0.0981 | |
| SRP159526 | ECHDC3 | 79746 | RNAseq | -1.3640 | 0.0094 | |
| SRP219564 | ECHDC3 | 79746 | RNAseq | -0.5695 | 0.4454 | |
| TCGA | ECHDC3 | 79746 | RNAseq | -0.5197 | 0.1033 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by ECHDC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ECHDC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ECHDC3 | 79746 | 6 | 7 | 17 | |
| GSE20123 | ECHDC3 | 79746 | 6 | 6 | 18 | |
| GSE43470 | ECHDC3 | 79746 | 3 | 5 | 35 | |
| GSE46452 | ECHDC3 | 79746 | 2 | 14 | 43 | |
| GSE47630 | ECHDC3 | 79746 | 6 | 14 | 20 | |
| GSE54993 | ECHDC3 | 79746 | 11 | 0 | 59 | |
| GSE54994 | ECHDC3 | 79746 | 4 | 9 | 40 | |
| GSE60625 | ECHDC3 | 79746 | 0 | 0 | 11 | |
| GSE74703 | ECHDC3 | 79746 | 2 | 3 | 31 | |
| GSE74704 | ECHDC3 | 79746 | 1 | 5 | 14 | |
| TCGA | ECHDC3 | 79746 | 19 | 24 | 53 |
Total number of gains: 60; Total number of losses: 87; Total Number of normals: 341.
Somatic mutations of ECHDC3:
Generating mutation plots.
Highly correlated genes for ECHDC3:
Showing top 20/573 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ECHDC3 | KRTAP20-1 | 0.814032 | 3 | 0 | 3 |
| ECHDC3 | OR2Z1 | 0.804578 | 3 | 0 | 3 |
| ECHDC3 | FAM163B | 0.791572 | 3 | 0 | 3 |
| ECHDC3 | NCCRP1 | 0.784498 | 3 | 0 | 3 |
| ECHDC3 | MFSD2B | 0.774695 | 3 | 0 | 3 |
| ECHDC3 | MUC22 | 0.7536 | 3 | 0 | 3 |
| ECHDC3 | DEGS2 | 0.751138 | 5 | 0 | 5 |
| ECHDC3 | IL12A-AS1 | 0.745914 | 3 | 0 | 3 |
| ECHDC3 | SPATA19 | 0.742906 | 4 | 0 | 4 |
| ECHDC3 | DCD | 0.739013 | 4 | 0 | 4 |
| ECHDC3 | TEAD3 | 0.731211 | 3 | 0 | 3 |
| ECHDC3 | C14orf180 | 0.73039 | 4 | 0 | 4 |
| ECHDC3 | KPRP | 0.727862 | 3 | 0 | 3 |
| ECHDC3 | ANKRD24 | 0.726126 | 4 | 0 | 4 |
| ECHDC3 | OR10G8 | 0.726059 | 3 | 0 | 3 |
| ECHDC3 | PLEKHN1 | 0.7227 | 5 | 0 | 5 |
| ECHDC3 | GALNT9 | 0.720716 | 5 | 0 | 5 |
| ECHDC3 | OTOP3 | 0.720627 | 3 | 0 | 3 |
| ECHDC3 | KCNA7 | 0.718534 | 4 | 0 | 4 |
| ECHDC3 | KMT2D | 0.7178 | 3 | 0 | 3 |
For details and further investigation, click here
