| Full name: EGF containing fibulin extracellular matrix protein 2 | Alias Symbol: FBLN4|UPH1 | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 30008 | HGNC ID: HGNC:3219 | Ensembl Gene: ENSG00000172638 | OMIM ID: 604633 |
| Drug and gene relationship at DGIdb | |||
Expression of EFEMP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFEMP2 | 30008 | 206580_s_at | -0.0772 | 0.9246 | |
| GSE20347 | EFEMP2 | 30008 | 206580_s_at | 0.5883 | 0.0016 | |
| GSE23400 | EFEMP2 | 30008 | 206580_s_at | 0.0667 | 0.4305 | |
| GSE26886 | EFEMP2 | 30008 | 206580_s_at | 1.9967 | 0.0000 | |
| GSE29001 | EFEMP2 | 30008 | 206580_s_at | 0.5256 | 0.2225 | |
| GSE38129 | EFEMP2 | 30008 | 206580_s_at | 0.1951 | 0.5085 | |
| GSE45670 | EFEMP2 | 30008 | 206580_s_at | -0.9319 | 0.0035 | |
| GSE53622 | EFEMP2 | 30008 | 48505 | 0.7013 | 0.0000 | |
| GSE53624 | EFEMP2 | 30008 | 48505 | 0.9037 | 0.0000 | |
| GSE63941 | EFEMP2 | 30008 | 206580_s_at | -5.3929 | 0.0000 | |
| GSE77861 | EFEMP2 | 30008 | 209356_x_at | 0.1953 | 0.3106 | |
| GSE97050 | EFEMP2 | 30008 | A_33_P3367830 | 0.1798 | 0.6083 | |
| SRP007169 | EFEMP2 | 30008 | RNAseq | 2.0636 | 0.0003 | |
| SRP008496 | EFEMP2 | 30008 | RNAseq | 2.9941 | 0.0000 | |
| SRP064894 | EFEMP2 | 30008 | RNAseq | 1.2317 | 0.0025 | |
| SRP133303 | EFEMP2 | 30008 | RNAseq | 0.6362 | 0.0663 | |
| SRP159526 | EFEMP2 | 30008 | RNAseq | 0.5077 | 0.1374 | |
| SRP193095 | EFEMP2 | 30008 | RNAseq | 1.3935 | 0.0000 | |
| SRP219564 | EFEMP2 | 30008 | RNAseq | 0.1216 | 0.8791 | |
| TCGA | EFEMP2 | 30008 | RNAseq | -0.1073 | 0.3932 |
Upregulated datasets: 5; Downregulated datasets: 1.
Survival by EFEMP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFEMP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFEMP2 | 30008 | 8 | 5 | 17 | |
| GSE20123 | EFEMP2 | 30008 | 8 | 5 | 17 | |
| GSE43470 | EFEMP2 | 30008 | 6 | 1 | 36 | |
| GSE46452 | EFEMP2 | 30008 | 11 | 3 | 45 | |
| GSE47630 | EFEMP2 | 30008 | 7 | 5 | 28 | |
| GSE54993 | EFEMP2 | 30008 | 3 | 0 | 67 | |
| GSE54994 | EFEMP2 | 30008 | 7 | 5 | 41 | |
| GSE60625 | EFEMP2 | 30008 | 0 | 3 | 8 | |
| GSE74703 | EFEMP2 | 30008 | 4 | 0 | 32 | |
| GSE74704 | EFEMP2 | 30008 | 6 | 3 | 11 | |
| TCGA | EFEMP2 | 30008 | 23 | 7 | 66 |
Total number of gains: 83; Total number of losses: 37; Total Number of normals: 368.
Somatic mutations of EFEMP2:
Generating mutation plots.
Highly correlated genes for EFEMP2:
Showing top 20/1489 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFEMP2 | FKBP7 | 0.800549 | 7 | 0 | 7 |
| EFEMP2 | KRTCAP2 | 0.793991 | 3 | 0 | 3 |
| EFEMP2 | AEBP1 | 0.791642 | 13 | 0 | 13 |
| EFEMP2 | CLMP | 0.789347 | 7 | 0 | 6 |
| EFEMP2 | ISLR | 0.783885 | 13 | 0 | 13 |
| EFEMP2 | COL6A1 | 0.782477 | 13 | 0 | 13 |
| EFEMP2 | SNAPC4 | 0.782275 | 3 | 0 | 3 |
| EFEMP2 | COL6A2 | 0.782182 | 13 | 0 | 13 |
| EFEMP2 | RNASEH2C | 0.781102 | 3 | 0 | 3 |
| EFEMP2 | FSTL1 | 0.777949 | 13 | 0 | 12 |
| EFEMP2 | LAMA4 | 0.7704 | 12 | 0 | 12 |
| EFEMP2 | COL8A1 | 0.769773 | 10 | 0 | 10 |
| EFEMP2 | A1BG | 0.768074 | 4 | 0 | 4 |
| EFEMP2 | MCAM | 0.767578 | 10 | 0 | 9 |
| EFEMP2 | ANGPTL4 | 0.764081 | 3 | 0 | 3 |
| EFEMP2 | ANO6 | 0.762998 | 8 | 0 | 8 |
| EFEMP2 | RILPL1 | 0.761715 | 4 | 0 | 4 |
| EFEMP2 | DNM3OS | 0.760143 | 3 | 0 | 3 |
| EFEMP2 | SLC39A13 | 0.758005 | 7 | 0 | 7 |
| EFEMP2 | RAB34 | 0.757289 | 3 | 0 | 3 |
For details and further investigation, click here
