| Full name: AE binding protein 1 | Alias Symbol: ACLP | ||
| Type: protein-coding gene | Cytoband: 7p13 | ||
| Entrez ID: 165 | HGNC ID: HGNC:303 | Ensembl Gene: ENSG00000106624 | OMIM ID: 602981 |
| Drug and gene relationship at DGIdb | |||
Expression of AEBP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AEBP1 | 165 | 201792_at | 0.1587 | 0.8932 | |
| GSE20347 | AEBP1 | 165 | 201792_at | 1.2473 | 0.0000 | |
| GSE23400 | AEBP1 | 165 | 201792_at | 0.6116 | 0.0004 | |
| GSE26886 | AEBP1 | 165 | 201792_at | 2.2731 | 0.0000 | |
| GSE29001 | AEBP1 | 165 | 201792_at | 1.2172 | 0.0001 | |
| GSE38129 | AEBP1 | 165 | 201792_at | 0.9097 | 0.0376 | |
| GSE45670 | AEBP1 | 165 | 201792_at | -1.0163 | 0.0322 | |
| GSE53622 | AEBP1 | 165 | 157658 | 0.9506 | 0.0000 | |
| GSE53624 | AEBP1 | 165 | 157658 | 1.1682 | 0.0000 | |
| GSE63941 | AEBP1 | 165 | 201792_at | -2.0679 | 0.0013 | |
| GSE77861 | AEBP1 | 165 | 201792_at | 0.3759 | 0.1393 | |
| GSE97050 | AEBP1 | 165 | A_23_P157299 | 0.7842 | 0.2750 | |
| SRP007169 | AEBP1 | 165 | RNAseq | 5.0335 | 0.0000 | |
| SRP008496 | AEBP1 | 165 | RNAseq | 5.2669 | 0.0000 | |
| SRP064894 | AEBP1 | 165 | RNAseq | 1.2673 | 0.0003 | |
| SRP133303 | AEBP1 | 165 | RNAseq | 1.4728 | 0.0004 | |
| SRP159526 | AEBP1 | 165 | RNAseq | 0.0773 | 0.8412 | |
| SRP193095 | AEBP1 | 165 | RNAseq | 2.8944 | 0.0000 | |
| SRP219564 | AEBP1 | 165 | RNAseq | 0.8383 | 0.0891 | |
| TCGA | AEBP1 | 165 | RNAseq | 0.0096 | 0.9254 |
Upregulated datasets: 9; Downregulated datasets: 2.
Survival by AEBP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AEBP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AEBP1 | 165 | 14 | 0 | 16 | |
| GSE20123 | AEBP1 | 165 | 13 | 0 | 17 | |
| GSE43470 | AEBP1 | 165 | 4 | 0 | 39 | |
| GSE46452 | AEBP1 | 165 | 11 | 1 | 47 | |
| GSE47630 | AEBP1 | 165 | 8 | 1 | 31 | |
| GSE54993 | AEBP1 | 165 | 0 | 8 | 62 | |
| GSE54994 | AEBP1 | 165 | 17 | 3 | 33 | |
| GSE60625 | AEBP1 | 165 | 0 | 0 | 11 | |
| GSE74703 | AEBP1 | 165 | 4 | 0 | 32 | |
| GSE74704 | AEBP1 | 165 | 7 | 0 | 13 | |
| TCGA | AEBP1 | 165 | 51 | 7 | 38 |
Total number of gains: 129; Total number of losses: 20; Total Number of normals: 339.
Somatic mutations of AEBP1:
Generating mutation plots.
Highly correlated genes for AEBP1:
Showing top 20/1237 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AEBP1 | COL8A1 | 0.824906 | 10 | 0 | 10 |
| AEBP1 | ISLR | 0.816899 | 13 | 0 | 13 |
| AEBP1 | COL6A1 | 0.813407 | 13 | 0 | 13 |
| AEBP1 | FN1 | 0.798085 | 12 | 0 | 12 |
| AEBP1 | COL6A2 | 0.79546 | 13 | 0 | 13 |
| AEBP1 | EFEMP2 | 0.791642 | 13 | 0 | 13 |
| AEBP1 | COL12A1 | 0.78889 | 9 | 0 | 9 |
| AEBP1 | PCOLCE | 0.781259 | 13 | 0 | 13 |
| AEBP1 | ANGPTL2 | 0.780478 | 13 | 0 | 13 |
| AEBP1 | VCAN | 0.776458 | 13 | 0 | 13 |
| AEBP1 | LGALS1 | 0.775815 | 12 | 0 | 12 |
| AEBP1 | SPARC | 0.772751 | 13 | 0 | 13 |
| AEBP1 | CTSK | 0.767812 | 13 | 0 | 13 |
| AEBP1 | HTRA1 | 0.765938 | 13 | 0 | 13 |
| AEBP1 | COL6A3 | 0.76387 | 13 | 0 | 13 |
| AEBP1 | FSTL1 | 0.762398 | 13 | 0 | 13 |
| AEBP1 | MICAL2 | 0.762058 | 10 | 0 | 9 |
| AEBP1 | MMP2 | 0.75702 | 12 | 0 | 11 |
| AEBP1 | FBN1 | 0.755679 | 11 | 0 | 11 |
| AEBP1 | COL5A1 | 0.752027 | 13 | 0 | 11 |
For details and further investigation, click here
