| Full name: alpha-1-B glycoprotein | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.43 | ||
| Entrez ID: 1 | HGNC ID: HGNC:5 | Ensembl Gene: ENSG00000121410 | OMIM ID: 138670 |
| Drug and gene relationship at DGIdb | |||
Expression of A1BG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | A1BG | 1 | 229819_at | 0.3947 | 0.4079 | |
| GSE26886 | A1BG | 1 | 229819_at | 0.9462 | 0.0000 | |
| GSE45670 | A1BG | 1 | 229819_at | 0.1682 | 0.2965 | |
| GSE63941 | A1BG | 1 | 229819_at | -1.6231 | 0.0004 | |
| GSE77861 | A1BG | 1 | 229819_at | -0.0464 | 0.7274 | |
| GSE97050 | A1BG | 1 | A_24_P151121 | 0.0372 | 0.8695 | |
| SRP007169 | A1BG | 1 | RNAseq | -0.3177 | 0.6610 | |
| SRP064894 | A1BG | 1 | RNAseq | 0.2917 | 0.3086 | |
| SRP133303 | A1BG | 1 | RNAseq | 0.0513 | 0.7021 | |
| SRP159526 | A1BG | 1 | RNAseq | 0.7475 | 0.0577 | |
| SRP193095 | A1BG | 1 | RNAseq | 0.0666 | 0.5958 | |
| SRP219564 | A1BG | 1 | RNAseq | 0.8648 | 0.0857 | |
| TCGA | A1BG | 1 | RNAseq | 0.5406 | 0.0041 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by A1BG expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of A1BG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | A1BG | 1 | 2 | 5 | 23 | |
| GSE20123 | A1BG | 1 | 2 | 4 | 24 | |
| GSE43470 | A1BG | 1 | 3 | 9 | 31 | |
| GSE46452 | A1BG | 1 | 45 | 1 | 13 | |
| GSE47630 | A1BG | 1 | 7 | 6 | 27 | |
| GSE54993 | A1BG | 1 | 18 | 4 | 48 | |
| GSE54994 | A1BG | 1 | 5 | 12 | 36 | |
| GSE60625 | A1BG | 1 | 9 | 0 | 2 | |
| GSE74703 | A1BG | 1 | 3 | 6 | 27 | |
| GSE74704 | A1BG | 1 | 2 | 1 | 17 | |
| TCGA | A1BG | 1 | 20 | 19 | 57 |
Total number of gains: 116; Total number of losses: 67; Total Number of normals: 305.
Somatic mutations of A1BG:
Generating mutation plots.
Highly correlated genes for A1BG:
Showing top 20/491 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| A1BG | WDR81 | 0.799608 | 3 | 0 | 3 |
| A1BG | TP53I13 | 0.79764 | 3 | 0 | 3 |
| A1BG | ACSL4 | 0.795885 | 3 | 0 | 3 |
| A1BG | FZD4 | 0.78771 | 3 | 0 | 3 |
| A1BG | C11orf96 | 0.780759 | 3 | 0 | 3 |
| A1BG | CDH6 | 0.777357 | 3 | 0 | 3 |
| A1BG | HGF | 0.772582 | 3 | 0 | 3 |
| A1BG | PXMP4 | 0.772575 | 3 | 0 | 3 |
| A1BG | ANGPTL4 | 0.772486 | 3 | 0 | 3 |
| A1BG | KCNAB2 | 0.77034 | 3 | 0 | 3 |
| A1BG | VSTM4 | 0.769583 | 3 | 0 | 3 |
| A1BG | EFEMP2 | 0.768074 | 4 | 0 | 4 |
| A1BG | AURKAIP1 | 0.765168 | 3 | 0 | 3 |
| A1BG | RGS1 | 0.764572 | 3 | 0 | 3 |
| A1BG | C2orf69 | 0.756963 | 3 | 0 | 3 |
| A1BG | POSTN | 0.752446 | 3 | 0 | 3 |
| A1BG | CD44 | 0.750891 | 3 | 0 | 3 |
| A1BG | RIT2 | 0.748915 | 3 | 0 | 3 |
| A1BG | PIEZO1 | 0.748859 | 3 | 0 | 3 |
| A1BG | NINJ1 | 0.748454 | 3 | 0 | 3 |
For details and further investigation, click here
