| Full name: elastin | Alias Symbol: WBS|WS|SVAS | ||
| Type: protein-coding gene | Cytoband: 7q11.23 | ||
| Entrez ID: 2006 | HGNC ID: HGNC:3327 | Ensembl Gene: ENSG00000049540 | OMIM ID: 130160 |
| Drug and gene relationship at DGIdb | |||
Expression of ELN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELN | 2006 | 212670_at | -0.7845 | 0.3636 | |
| GSE20347 | ELN | 2006 | 212670_at | -0.1306 | 0.5743 | |
| GSE23400 | ELN | 2006 | 212670_at | -0.2906 | 0.0678 | |
| GSE26886 | ELN | 2006 | 212670_at | 0.2777 | 0.0262 | |
| GSE29001 | ELN | 2006 | 212670_at | -0.1141 | 0.6977 | |
| GSE38129 | ELN | 2006 | 212670_at | -0.3987 | 0.0981 | |
| GSE45670 | ELN | 2006 | 212670_at | -0.2927 | 0.0345 | |
| GSE53622 | ELN | 2006 | 17657 | -2.7442 | 0.0000 | |
| GSE53624 | ELN | 2006 | 17657 | -3.1337 | 0.0000 | |
| GSE63941 | ELN | 2006 | 212670_at | -1.0600 | 0.0002 | |
| GSE77861 | ELN | 2006 | 216269_s_at | -0.0956 | 0.4580 | |
| GSE97050 | ELN | 2006 | A_24_P186943 | -1.1134 | 0.2237 | |
| SRP007169 | ELN | 2006 | RNAseq | 0.5121 | 0.2606 | |
| SRP008496 | ELN | 2006 | RNAseq | 1.6955 | 0.0368 | |
| SRP064894 | ELN | 2006 | RNAseq | 0.0422 | 0.9387 | |
| SRP133303 | ELN | 2006 | RNAseq | -0.8227 | 0.0965 | |
| SRP159526 | ELN | 2006 | RNAseq | -1.0648 | 0.0570 | |
| SRP193095 | ELN | 2006 | RNAseq | 0.0891 | 0.7954 | |
| SRP219564 | ELN | 2006 | RNAseq | -0.5754 | 0.5999 | |
| TCGA | ELN | 2006 | RNAseq | -0.5403 | 0.0126 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by ELN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELN | 2006 | 14 | 1 | 15 | |
| GSE20123 | ELN | 2006 | 14 | 1 | 15 | |
| GSE43470 | ELN | 2006 | 3 | 2 | 38 | |
| GSE46452 | ELN | 2006 | 12 | 0 | 47 | |
| GSE47630 | ELN | 2006 | 7 | 2 | 31 | |
| GSE54993 | ELN | 2006 | 2 | 7 | 61 | |
| GSE54994 | ELN | 2006 | 13 | 3 | 37 | |
| GSE60625 | ELN | 2006 | 0 | 0 | 11 | |
| GSE74703 | ELN | 2006 | 3 | 1 | 32 | |
| GSE74704 | ELN | 2006 | 8 | 1 | 11 | |
| TCGA | ELN | 2006 | 45 | 7 | 44 |
Total number of gains: 121; Total number of losses: 25; Total Number of normals: 342.
Somatic mutations of ELN:
Generating mutation plots.
Highly correlated genes for ELN:
Showing top 20/434 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELN | BOK | 0.863403 | 3 | 0 | 3 |
| ELN | NCCRP1 | 0.848233 | 3 | 0 | 3 |
| ELN | IQCF1 | 0.83969 | 4 | 0 | 4 |
| ELN | KRTAP20-1 | 0.831592 | 3 | 0 | 3 |
| ELN | CSTL1 | 0.82815 | 3 | 0 | 3 |
| ELN | OR2Z1 | 0.820381 | 3 | 0 | 3 |
| ELN | GPX6 | 0.819692 | 3 | 0 | 3 |
| ELN | FAM163B | 0.817386 | 3 | 0 | 3 |
| ELN | CYP3A7 | 0.813877 | 3 | 0 | 3 |
| ELN | MYZAP | 0.803008 | 3 | 0 | 3 |
| ELN | OR5AS1 | 0.787174 | 3 | 0 | 3 |
| ELN | C3orf20 | 0.784303 | 3 | 0 | 3 |
| ELN | MFSD2B | 0.780365 | 3 | 0 | 3 |
| ELN | MUC22 | 0.779935 | 3 | 0 | 3 |
| ELN | ANKRD24 | 0.775666 | 4 | 0 | 4 |
| ELN | KPRP | 0.774819 | 3 | 0 | 3 |
| ELN | OTOP3 | 0.773931 | 3 | 0 | 3 |
| ELN | ACOT12 | 0.773516 | 3 | 0 | 3 |
| ELN | FAM180B | 0.770046 | 3 | 0 | 3 |
| ELN | BTBD19 | 0.76871 | 5 | 0 | 5 |
For details and further investigation, click here
