| Full name: family with sequence similarity 180 member B | Alias Symbol: LOC399888 | ||
| Type: protein-coding gene | Cytoband: 11p11.2 | ||
| Entrez ID: 399888 | HGNC ID: HGNC:34451 | Ensembl Gene: ENSG00000196666 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM180B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | FAM180B | 399888 | 18967 | -0.7787 | 0.0000 | |
| GSE53624 | FAM180B | 399888 | 18967 | -0.7751 | 0.0000 | |
| GSE97050 | FAM180B | 399888 | A_33_P3330404 | -0.4128 | 0.3194 | |
| SRP133303 | FAM180B | 399888 | RNAseq | -0.6384 | 0.0313 | |
| TCGA | FAM180B | 399888 | RNAseq | -3.7717 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by FAM180B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM180B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM180B | 399888 | 3 | 7 | 20 | |
| GSE20123 | FAM180B | 399888 | 3 | 6 | 21 | |
| GSE43470 | FAM180B | 399888 | 1 | 4 | 38 | |
| GSE46452 | FAM180B | 399888 | 8 | 5 | 46 | |
| GSE47630 | FAM180B | 399888 | 3 | 9 | 28 | |
| GSE54993 | FAM180B | 399888 | 3 | 0 | 67 | |
| GSE54994 | FAM180B | 399888 | 1 | 11 | 41 | |
| GSE60625 | FAM180B | 399888 | 0 | 0 | 11 | |
| GSE74703 | FAM180B | 399888 | 1 | 2 | 33 | |
| GSE74704 | FAM180B | 399888 | 2 | 4 | 14 | |
| TCGA | FAM180B | 399888 | 10 | 20 | 66 |
Total number of gains: 35; Total number of losses: 68; Total Number of normals: 385.
Somatic mutations of FAM180B:
Generating mutation plots.
Highly correlated genes for FAM180B:
Showing top 20/74 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM180B | IGSF1 | 0.807695 | 3 | 0 | 3 |
| FAM180B | GPSM1 | 0.789928 | 3 | 0 | 3 |
| FAM180B | ELN | 0.770046 | 3 | 0 | 3 |
| FAM180B | MORN3 | 0.769347 | 3 | 0 | 3 |
| FAM180B | TOLLIP | 0.767204 | 3 | 0 | 3 |
| FAM180B | CRHR1 | 0.73272 | 3 | 0 | 3 |
| FAM180B | OXT | 0.731213 | 3 | 0 | 3 |
| FAM180B | GALNT9 | 0.719445 | 3 | 0 | 3 |
| FAM180B | UBL3 | 0.713176 | 3 | 0 | 3 |
| FAM180B | KRTAP20-1 | 0.709412 | 3 | 0 | 3 |
| FAM180B | OR2Z1 | 0.705225 | 3 | 0 | 3 |
| FAM180B | BOK | 0.700165 | 3 | 0 | 3 |
| FAM180B | ANKRD24 | 0.697514 | 3 | 0 | 3 |
| FAM180B | AIF1L | 0.696968 | 3 | 0 | 3 |
| FAM180B | NANOS2 | 0.696747 | 3 | 0 | 3 |
| FAM180B | MFSD2B | 0.68695 | 3 | 0 | 3 |
| FAM180B | OTOF | 0.685598 | 3 | 0 | 3 |
| FAM180B | CLPS | 0.677263 | 3 | 0 | 3 |
| FAM180B | KRT78 | 0.675954 | 3 | 0 | 3 |
| FAM180B | WNK4 | 0.672709 | 3 | 0 | 3 |
For details and further investigation, click here
