| Full name: acyl-CoA thioesterase 12 | Alias Symbol: Cach|THEAL|STARD15 | ||
| Type: protein-coding gene | Cytoband: 5q14.1 | ||
| Entrez ID: 134526 | HGNC ID: HGNC:24436 | Ensembl Gene: ENSG00000172497 | OMIM ID: 614315 |
| Drug and gene relationship at DGIdb | |||
Expression of ACOT12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ACOT12 | 134526 | 238160_at | 0.0035 | 0.9921 | |
| GSE26886 | ACOT12 | 134526 | 238160_at | -0.0271 | 0.7644 | |
| GSE45670 | ACOT12 | 134526 | 238160_at | 0.0525 | 0.3798 | |
| GSE53622 | ACOT12 | 134526 | 60480 | -2.2878 | 0.0000 | |
| GSE53624 | ACOT12 | 134526 | 60480 | -2.1577 | 0.0000 | |
| GSE63941 | ACOT12 | 134526 | 238160_at | -0.4763 | 0.0024 | |
| GSE77861 | ACOT12 | 134526 | 238160_at | -0.0863 | 0.2485 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by ACOT12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ACOT12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ACOT12 | 134526 | 1 | 13 | 16 | |
| GSE20123 | ACOT12 | 134526 | 1 | 13 | 16 | |
| GSE43470 | ACOT12 | 134526 | 2 | 11 | 30 | |
| GSE46452 | ACOT12 | 134526 | 0 | 28 | 31 | |
| GSE47630 | ACOT12 | 134526 | 1 | 19 | 20 | |
| GSE54993 | ACOT12 | 134526 | 8 | 1 | 61 | |
| GSE54994 | ACOT12 | 134526 | 2 | 18 | 33 | |
| GSE60625 | ACOT12 | 134526 | 0 | 0 | 11 | |
| GSE74703 | ACOT12 | 134526 | 1 | 7 | 28 | |
| GSE74704 | ACOT12 | 134526 | 1 | 6 | 13 | |
| TCGA | ACOT12 | 134526 | 5 | 49 | 42 |
Total number of gains: 22; Total number of losses: 165; Total Number of normals: 301.
Somatic mutations of ACOT12:
Generating mutation plots.
Highly correlated genes for ACOT12:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ACOT12 | ELN | 0.773516 | 3 | 0 | 3 |
| ACOT12 | YOD1 | 0.768463 | 3 | 0 | 3 |
| ACOT12 | TMOD3 | 0.767838 | 3 | 0 | 3 |
| ACOT12 | PHACTR2 | 0.761078 | 3 | 0 | 3 |
| ACOT12 | ITSN2 | 0.759575 | 3 | 0 | 3 |
| ACOT12 | FAM214A | 0.754171 | 3 | 0 | 3 |
| ACOT12 | DHRS1 | 0.753475 | 3 | 0 | 3 |
| ACOT12 | RAB10 | 0.752386 | 3 | 0 | 3 |
| ACOT12 | C18orf25 | 0.747565 | 3 | 0 | 3 |
| ACOT12 | SH3D19 | 0.734637 | 4 | 0 | 4 |
| ACOT12 | EPS8L2 | 0.729293 | 3 | 0 | 3 |
| ACOT12 | P2RX3 | 0.729275 | 3 | 0 | 3 |
| ACOT12 | C5orf66-AS1 | 0.726029 | 3 | 0 | 3 |
| ACOT12 | KIAA0232 | 0.724712 | 3 | 0 | 3 |
| ACOT12 | KRT78 | 0.724052 | 3 | 0 | 3 |
| ACOT12 | BBOX1 | 0.723972 | 3 | 0 | 3 |
| ACOT12 | FCHO2 | 0.723576 | 3 | 0 | 3 |
| ACOT12 | KRT32 | 0.721599 | 3 | 0 | 3 |
| ACOT12 | ARHGEF10L | 0.720783 | 3 | 0 | 3 |
| ACOT12 | HSDL2 | 0.718853 | 3 | 0 | 3 |
For details and further investigation, click here
