| Full name: myocardial zonula adherens protein | Alias Symbol: MYOZAP|Gup|Gup1|GCOM1 | ||
| Type: protein-coding gene | Cytoband: 15q21.3 | ||
| Entrez ID: 100820829 | HGNC ID: HGNC:43444 | Ensembl Gene: ENSG00000263155 | OMIM ID: 614071 |
| Drug and gene relationship at DGIdb | |||
Expression of MYZAP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | MYZAP | 100820829 | 8423 | -4.3095 | 0.0000 | |
| GSE53624 | MYZAP | 100820829 | 8423 | -4.4615 | 0.0000 | |
| GSE97050 | MYZAP | 100820829 | A_23_P129144 | -1.6899 | 0.1421 | |
| SRP007169 | MYZAP | 100820829 | RNAseq | -6.0259 | 0.0047 | |
| SRP064894 | MYZAP | 100820829 | RNAseq | -3.9929 | 0.0000 | |
| SRP133303 | MYZAP | 100820829 | RNAseq | -3.8814 | 0.0000 | |
| SRP159526 | MYZAP | 100820829 | RNAseq | -4.5465 | 0.0000 | |
| SRP193095 | MYZAP | 100820829 | RNAseq | -4.5242 | 0.0000 | |
| SRP219564 | MYZAP | 100820829 | RNAseq | -2.7374 | 0.0012 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by MYZAP expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of MYZAP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYZAP | 100820829 | 6 | 4 | 20 | |
| GSE20123 | MYZAP | 100820829 | 6 | 3 | 21 | |
| GSE43470 | MYZAP | 100820829 | 4 | 4 | 35 | |
| GSE46452 | MYZAP | 100820829 | 3 | 7 | 49 | |
| GSE47630 | MYZAP | 100820829 | 8 | 10 | 22 | |
| GSE54993 | MYZAP | 100820829 | 5 | 6 | 59 | |
| GSE54994 | MYZAP | 100820829 | 6 | 8 | 39 | |
| GSE60625 | MYZAP | 100820829 | 4 | 0 | 7 | |
| GSE74703 | MYZAP | 100820829 | 4 | 3 | 29 | |
| GSE74704 | MYZAP | 100820829 | 2 | 3 | 15 | |
| TCGA | MYZAP | 100820829 | 10 | 16 | 70 |
Total number of gains: 58; Total number of losses: 64; Total Number of normals: 366.
Somatic mutations of MYZAP:
Generating mutation plots.
Highly correlated genes for MYZAP:
Showing top 20/192 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYZAP | ARHGAP10 | 0.872811 | 3 | 0 | 3 |
| MYZAP | KIAA0232 | 0.871906 | 3 | 0 | 3 |
| MYZAP | UBL3 | 0.869029 | 3 | 0 | 3 |
| MYZAP | HSPB8 | 0.865484 | 3 | 0 | 3 |
| MYZAP | CTTNBP2 | 0.851606 | 3 | 0 | 3 |
| MYZAP | TP53INP2 | 0.850864 | 3 | 0 | 3 |
| MYZAP | TRNP1 | 0.849292 | 3 | 0 | 3 |
| MYZAP | PPP1R3C | 0.840667 | 3 | 0 | 3 |
| MYZAP | SH3BGRL2 | 0.83189 | 3 | 0 | 3 |
| MYZAP | EPHX2 | 0.829072 | 3 | 0 | 3 |
| MYZAP | ARID5A | 0.825051 | 3 | 0 | 3 |
| MYZAP | IL11RA | 0.823584 | 3 | 0 | 3 |
| MYZAP | MAPT | 0.821621 | 3 | 0 | 3 |
| MYZAP | TOM1L2 | 0.821477 | 3 | 0 | 3 |
| MYZAP | PDK4 | 0.819602 | 3 | 0 | 3 |
| MYZAP | FAM107A | 0.817883 | 3 | 0 | 3 |
| MYZAP | KRT78 | 0.81726 | 3 | 0 | 3 |
| MYZAP | MGLL | 0.815717 | 3 | 0 | 3 |
| MYZAP | AHNAK | 0.811097 | 3 | 0 | 3 |
| MYZAP | SHROOM3 | 0.810277 | 3 | 0 | 3 |
For details and further investigation, click here
