| Full name: cystatin like 1 | Alias Symbol: dJ322G13.4|CTES1 | ||
| Type: protein-coding gene | Cytoband: 20p11.21 | ||
| Entrez ID: 128817 | HGNC ID: HGNC:15958 | Ensembl Gene: ENSG00000125823 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of CSTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CSTL1 | 128817 | 234803_at | 0.2030 | 0.3210 | |
| GSE26886 | CSTL1 | 128817 | 234803_at | -0.0174 | 0.8701 | |
| GSE45670 | CSTL1 | 128817 | 234803_at | 0.1342 | 0.0967 | |
| GSE53622 | CSTL1 | 128817 | 48238 | -2.4043 | 0.0000 | |
| GSE53624 | CSTL1 | 128817 | 48238 | -2.2729 | 0.0000 | |
| GSE63941 | CSTL1 | 128817 | 234803_at | 0.2417 | 0.1220 | |
| GSE77861 | CSTL1 | 128817 | 234803_at | -0.1285 | 0.2401 | |
| GSE97050 | CSTL1 | 128817 | A_33_P3381087 | -0.7052 | 0.2094 | |
| TCGA | CSTL1 | 128817 | RNAseq | 2.8604 | 0.0009 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by CSTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CSTL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CSTL1 | 128817 | 13 | 1 | 16 | |
| GSE20123 | CSTL1 | 128817 | 13 | 1 | 16 | |
| GSE43470 | CSTL1 | 128817 | 12 | 1 | 30 | |
| GSE46452 | CSTL1 | 128817 | 27 | 1 | 31 | |
| GSE47630 | CSTL1 | 128817 | 17 | 4 | 19 | |
| GSE54993 | CSTL1 | 128817 | 0 | 17 | 53 | |
| GSE54994 | CSTL1 | 128817 | 26 | 2 | 25 | |
| GSE60625 | CSTL1 | 128817 | 0 | 0 | 11 | |
| GSE74703 | CSTL1 | 128817 | 10 | 1 | 25 | |
| GSE74704 | CSTL1 | 128817 | 7 | 1 | 12 | |
| TCGA | CSTL1 | 128817 | 43 | 10 | 43 |
Total number of gains: 168; Total number of losses: 39; Total Number of normals: 281.
Somatic mutations of CSTL1:
Generating mutation plots.
Highly correlated genes for CSTL1:
Showing top 20/202 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CSTL1 | OTOF | 0.904913 | 3 | 0 | 3 |
| CSTL1 | OR2Z1 | 0.898183 | 3 | 0 | 3 |
| CSTL1 | KRTAP20-1 | 0.887632 | 3 | 0 | 3 |
| CSTL1 | OR10G8 | 0.885524 | 3 | 0 | 3 |
| CSTL1 | FAM163B | 0.884846 | 3 | 0 | 3 |
| CSTL1 | UPB1 | 0.873204 | 4 | 0 | 4 |
| CSTL1 | MFSD2B | 0.861968 | 3 | 0 | 3 |
| CSTL1 | NCCRP1 | 0.847567 | 3 | 0 | 3 |
| CSTL1 | C19orf57 | 0.846207 | 3 | 0 | 3 |
| CSTL1 | ELN | 0.82815 | 3 | 0 | 3 |
| CSTL1 | OTOP3 | 0.813236 | 3 | 0 | 3 |
| CSTL1 | MUC22 | 0.812214 | 3 | 0 | 3 |
| CSTL1 | BARHL2 | 0.797809 | 3 | 0 | 3 |
| CSTL1 | KPRP | 0.797382 | 3 | 0 | 3 |
| CSTL1 | KRT83 | 0.793919 | 3 | 0 | 3 |
| CSTL1 | RNF151 | 0.792953 | 3 | 0 | 3 |
| CSTL1 | TEN1 | 0.791293 | 3 | 0 | 3 |
| CSTL1 | TMPRSS11A | 0.789955 | 3 | 0 | 3 |
| CSTL1 | OR5AS1 | 0.785709 | 3 | 0 | 3 |
| CSTL1 | RNF222 | 0.778543 | 3 | 0 | 3 |
For details and further investigation, click here
