| Full name: ELOVL fatty acid elongase 3 | Alias Symbol: CIG-30 | ||
| Type: protein-coding gene | Cytoband: 10q24.32 | ||
| Entrez ID: 83401 | HGNC ID: HGNC:18047 | Ensembl Gene: ENSG00000119915 | OMIM ID: 611815 |
| Drug and gene relationship at DGIdb | |||
Expression of ELOVL3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELOVL3 | 83401 | 234513_at | 0.7438 | 0.1643 | |
| GSE26886 | ELOVL3 | 83401 | 234513_at | 0.0898 | 0.2645 | |
| GSE45670 | ELOVL3 | 83401 | 234513_at | 0.2667 | 0.0933 | |
| GSE53622 | ELOVL3 | 83401 | 92144 | 0.3979 | 0.0000 | |
| GSE53624 | ELOVL3 | 83401 | 92144 | 0.4045 | 0.0001 | |
| GSE63941 | ELOVL3 | 83401 | 234513_at | -0.0884 | 0.7651 | |
| GSE77861 | ELOVL3 | 83401 | 234513_at | 0.0493 | 0.5808 | |
| GSE97050 | ELOVL3 | 83401 | A_23_P149858 | 0.2507 | 0.2433 | |
| TCGA | ELOVL3 | 83401 | RNAseq | 2.2095 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ELOVL3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOVL3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOVL3 | 83401 | 2 | 9 | 19 | |
| GSE20123 | ELOVL3 | 83401 | 2 | 8 | 20 | |
| GSE43470 | ELOVL3 | 83401 | 0 | 8 | 35 | |
| GSE46452 | ELOVL3 | 83401 | 0 | 11 | 48 | |
| GSE47630 | ELOVL3 | 83401 | 2 | 14 | 24 | |
| GSE54993 | ELOVL3 | 83401 | 8 | 0 | 62 | |
| GSE54994 | ELOVL3 | 83401 | 1 | 12 | 40 | |
| GSE60625 | ELOVL3 | 83401 | 0 | 0 | 11 | |
| GSE74703 | ELOVL3 | 83401 | 0 | 5 | 31 | |
| GSE74704 | ELOVL3 | 83401 | 1 | 4 | 15 | |
| TCGA | ELOVL3 | 83401 | 5 | 29 | 62 |
Total number of gains: 21; Total number of losses: 100; Total Number of normals: 367.
Somatic mutations of ELOVL3:
Generating mutation plots.
Highly correlated genes for ELOVL3:
Showing top 20/247 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOVL3 | STRC | 0.783004 | 3 | 0 | 3 |
| ELOVL3 | PDZD7 | 0.772796 | 3 | 0 | 3 |
| ELOVL3 | CPNE7 | 0.765872 | 3 | 0 | 3 |
| ELOVL3 | TMEM235 | 0.756557 | 3 | 0 | 3 |
| ELOVL3 | LHB | 0.755001 | 3 | 0 | 3 |
| ELOVL3 | SHISA7 | 0.752466 | 3 | 0 | 3 |
| ELOVL3 | C19orf71 | 0.752434 | 3 | 0 | 3 |
| ELOVL3 | OR2A5 | 0.751605 | 3 | 0 | 3 |
| ELOVL3 | SLC22A11 | 0.751484 | 3 | 0 | 3 |
| ELOVL3 | SPACA3 | 0.751262 | 3 | 0 | 3 |
| ELOVL3 | LRRC10 | 0.748474 | 3 | 0 | 3 |
| ELOVL3 | PM20D1 | 0.746035 | 3 | 0 | 3 |
| ELOVL3 | SLC22A25 | 0.741489 | 3 | 0 | 3 |
| ELOVL3 | C9orf153 | 0.740164 | 3 | 0 | 3 |
| ELOVL3 | CNOT3 | 0.740035 | 4 | 0 | 4 |
| ELOVL3 | COL16A1 | 0.738006 | 3 | 0 | 3 |
| ELOVL3 | MS4A18 | 0.735061 | 3 | 0 | 3 |
| ELOVL3 | GPR182 | 0.733698 | 3 | 0 | 3 |
| ELOVL3 | DCDC1 | 0.733539 | 3 | 0 | 3 |
| ELOVL3 | SLC18A3 | 0.732718 | 4 | 0 | 4 |
For details and further investigation, click here
