| Full name: solute carrier family 18 member A3 | Alias Symbol: VACHT | ||
| Type: protein-coding gene | Cytoband: 10q11.23 | ||
| Entrez ID: 6572 | HGNC ID: HGNC:10936 | Ensembl Gene: ENSG00000187714 | OMIM ID: 600336 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC18A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC18A3 | 6572 | 207150_at | 0.1586 | 0.3957 | |
| GSE20347 | SLC18A3 | 6572 | 207150_at | 0.0591 | 0.6374 | |
| GSE23400 | SLC18A3 | 6572 | 207150_at | -0.0020 | 0.9462 | |
| GSE26886 | SLC18A3 | 6572 | 207150_at | 0.2541 | 0.3082 | |
| GSE29001 | SLC18A3 | 6572 | 207150_at | -0.0066 | 0.9674 | |
| GSE38129 | SLC18A3 | 6572 | 207150_at | 0.0364 | 0.7648 | |
| GSE45670 | SLC18A3 | 6572 | 207150_at | -0.0247 | 0.8339 | |
| GSE53622 | SLC18A3 | 6572 | 84113 | 0.1109 | 0.2818 | |
| GSE53624 | SLC18A3 | 6572 | 84113 | -0.1451 | 0.2428 | |
| GSE63941 | SLC18A3 | 6572 | 207150_at | 0.1043 | 0.3674 | |
| GSE77861 | SLC18A3 | 6572 | 207150_at | -0.0091 | 0.9643 | |
| GSE97050 | SLC18A3 | 6572 | A_33_P3270317 | -0.0512 | 0.8089 | |
| TCGA | SLC18A3 | 6572 | RNAseq | -0.2836 | 0.7339 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC18A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC18A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC18A3 | 6572 | 2 | 5 | 23 | |
| GSE20123 | SLC18A3 | 6572 | 2 | 5 | 23 | |
| GSE43470 | SLC18A3 | 6572 | 2 | 6 | 35 | |
| GSE46452 | SLC18A3 | 6572 | 0 | 13 | 46 | |
| GSE47630 | SLC18A3 | 6572 | 4 | 12 | 24 | |
| GSE54993 | SLC18A3 | 6572 | 9 | 0 | 61 | |
| GSE54994 | SLC18A3 | 6572 | 2 | 10 | 41 | |
| GSE60625 | SLC18A3 | 6572 | 0 | 0 | 11 | |
| GSE74703 | SLC18A3 | 6572 | 2 | 3 | 31 | |
| GSE74704 | SLC18A3 | 6572 | 1 | 4 | 15 | |
| TCGA | SLC18A3 | 6572 | 12 | 22 | 62 |
Total number of gains: 36; Total number of losses: 80; Total Number of normals: 372.
Somatic mutations of SLC18A3:
Generating mutation plots.
Highly correlated genes for SLC18A3:
Showing top 20/526 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC18A3 | STRC | 0.864596 | 3 | 0 | 3 |
| SLC18A3 | YY2 | 0.847926 | 3 | 0 | 3 |
| SLC18A3 | FBRSL1 | 0.839104 | 3 | 0 | 3 |
| SLC18A3 | DCDC1 | 0.838216 | 3 | 0 | 3 |
| SLC18A3 | DEFB121 | 0.830302 | 3 | 0 | 3 |
| SLC18A3 | OR2T27 | 0.823594 | 3 | 0 | 3 |
| SLC18A3 | KCP | 0.814497 | 4 | 0 | 4 |
| SLC18A3 | C9orf153 | 0.810612 | 3 | 0 | 3 |
| SLC18A3 | PRSS38 | 0.802885 | 3 | 0 | 3 |
| SLC18A3 | PLA2G2C | 0.797893 | 3 | 0 | 3 |
| SLC18A3 | BBC3 | 0.79412 | 3 | 0 | 3 |
| SLC18A3 | VAV2 | 0.793911 | 3 | 0 | 3 |
| SLC18A3 | PGC | 0.793224 | 3 | 0 | 3 |
| SLC18A3 | FOXA3 | 0.78743 | 4 | 0 | 4 |
| SLC18A3 | C1QTNF6 | 0.783912 | 3 | 0 | 3 |
| SLC18A3 | KIRREL2 | 0.783842 | 4 | 0 | 4 |
| SLC18A3 | OR10AD1 | 0.780946 | 3 | 0 | 3 |
| SLC18A3 | LBX2 | 0.777067 | 3 | 0 | 3 |
| SLC18A3 | KRTAP10-12 | 0.776242 | 3 | 0 | 3 |
| SLC18A3 | OR2A5 | 0.774868 | 3 | 0 | 3 |
For details and further investigation, click here
