| Full name: leucine rich repeat containing 10 | Alias Symbol: HRLRRP|LRRC10A | ||
| Type: protein-coding gene | Cytoband: 12q15 | ||
| Entrez ID: 376132 | HGNC ID: HGNC:20264 | Ensembl Gene: ENSG00000198812 | OMIM ID: 610846 |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | LRRC10 | 376132 | 8674 | 0.6466 | 0.0000 | |
| GSE53624 | LRRC10 | 376132 | 8674 | 0.4674 | 0.0000 | |
| GSE97050 | LRRC10 | 376132 | A_33_P3388865 | 0.2645 | 0.3605 | |
| SRP133303 | LRRC10 | 376132 | RNAseq | 0.2504 | 0.2403 | |
| TCGA | LRRC10 | 376132 | RNAseq | 1.4120 | 0.5709 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC10 | 376132 | 6 | 1 | 23 | |
| GSE20123 | LRRC10 | 376132 | 6 | 0 | 24 | |
| GSE43470 | LRRC10 | 376132 | 4 | 0 | 39 | |
| GSE46452 | LRRC10 | 376132 | 10 | 1 | 48 | |
| GSE47630 | LRRC10 | 376132 | 10 | 1 | 29 | |
| GSE54993 | LRRC10 | 376132 | 0 | 6 | 64 | |
| GSE54994 | LRRC10 | 376132 | 8 | 1 | 44 | |
| GSE60625 | LRRC10 | 376132 | 0 | 0 | 11 | |
| GSE74703 | LRRC10 | 376132 | 4 | 0 | 32 | |
| GSE74704 | LRRC10 | 376132 | 5 | 0 | 15 | |
| TCGA | LRRC10 | 376132 | 23 | 8 | 65 |
Total number of gains: 76; Total number of losses: 18; Total Number of normals: 394.
Somatic mutations of LRRC10:
Generating mutation plots.
Highly correlated genes for LRRC10:
Showing top 20/71 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC10 | SLC6A3 | 0.788315 | 3 | 0 | 3 |
| LRRC10 | GNB3 | 0.767617 | 3 | 0 | 3 |
| LRRC10 | SHISA7 | 0.764733 | 3 | 0 | 3 |
| LRRC10 | CCL25 | 0.757107 | 3 | 0 | 3 |
| LRRC10 | PDZD7 | 0.750459 | 3 | 0 | 3 |
| LRRC10 | MEGF11 | 0.749919 | 3 | 0 | 3 |
| LRRC10 | ELOVL3 | 0.748474 | 3 | 0 | 3 |
| LRRC10 | IL1F10 | 0.747442 | 3 | 0 | 3 |
| LRRC10 | ADRA1A | 0.745825 | 3 | 0 | 3 |
| LRRC10 | FGF22 | 0.743537 | 3 | 0 | 3 |
| LRRC10 | ANKDD1A | 0.740675 | 3 | 0 | 3 |
| LRRC10 | PRLH | 0.739923 | 3 | 0 | 3 |
| LRRC10 | NPPB | 0.739783 | 3 | 0 | 3 |
| LRRC10 | STRC | 0.737976 | 3 | 0 | 3 |
| LRRC10 | PRAP1 | 0.737058 | 3 | 0 | 3 |
| LRRC10 | NTNG2 | 0.731438 | 3 | 0 | 3 |
| LRRC10 | POM121L12 | 0.731222 | 3 | 0 | 3 |
| LRRC10 | LTK | 0.729234 | 3 | 0 | 3 |
| LRRC10 | LHB | 0.726799 | 3 | 0 | 3 |
| LRRC10 | CDHR5 | 0.7235 | 3 | 0 | 3 |
For details and further investigation, click here
