| Full name: killer cell lectin like receptor G1 | Alias Symbol: MAFA|2F1|MAFA-L|CLEC15A | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 10219 | HGNC ID: HGNC:6380 | Ensembl Gene: ENSG00000139187 | OMIM ID: 604874 |
| Drug and gene relationship at DGIdb | |||
Expression of KLRG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLRG1 | 10219 | 210288_at | -0.1712 | 0.5703 | |
| GSE20347 | KLRG1 | 10219 | 210288_at | -0.1886 | 0.0341 | |
| GSE23400 | KLRG1 | 10219 | 210288_at | -0.1556 | 0.0024 | |
| GSE26886 | KLRG1 | 10219 | 210288_at | -0.1668 | 0.1600 | |
| GSE29001 | KLRG1 | 10219 | 210288_at | -0.1964 | 0.2148 | |
| GSE38129 | KLRG1 | 10219 | 210288_at | -0.2821 | 0.0008 | |
| GSE45670 | KLRG1 | 10219 | 210288_at | -0.2351 | 0.0516 | |
| GSE53622 | KLRG1 | 10219 | 138844 | -0.7808 | 0.0000 | |
| GSE53624 | KLRG1 | 10219 | 12027 | -0.4810 | 0.0116 | |
| GSE63941 | KLRG1 | 10219 | 210288_at | 0.2953 | 0.3572 | |
| GSE77861 | KLRG1 | 10219 | 210288_at | -0.0461 | 0.6477 | |
| GSE97050 | KLRG1 | 10219 | A_24_P261760 | 0.1399 | 0.6751 | |
| SRP064894 | KLRG1 | 10219 | RNAseq | -0.0768 | 0.7234 | |
| SRP133303 | KLRG1 | 10219 | RNAseq | -0.0608 | 0.6266 | |
| SRP159526 | KLRG1 | 10219 | RNAseq | -0.5701 | 0.0870 | |
| SRP193095 | KLRG1 | 10219 | RNAseq | 0.1619 | 0.2278 | |
| SRP219564 | KLRG1 | 10219 | RNAseq | -0.2848 | 0.5400 | |
| TCGA | KLRG1 | 10219 | RNAseq | -0.7892 | 0.0149 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLRG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLRG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLRG1 | 10219 | 6 | 3 | 21 | |
| GSE20123 | KLRG1 | 10219 | 6 | 3 | 21 | |
| GSE43470 | KLRG1 | 10219 | 8 | 3 | 32 | |
| GSE46452 | KLRG1 | 10219 | 10 | 1 | 48 | |
| GSE47630 | KLRG1 | 10219 | 12 | 2 | 26 | |
| GSE54993 | KLRG1 | 10219 | 1 | 10 | 59 | |
| GSE54994 | KLRG1 | 10219 | 9 | 2 | 42 | |
| GSE60625 | KLRG1 | 10219 | 0 | 1 | 10 | |
| GSE74703 | KLRG1 | 10219 | 8 | 2 | 26 | |
| GSE74704 | KLRG1 | 10219 | 4 | 2 | 14 | |
| TCGA | KLRG1 | 10219 | 40 | 6 | 50 |
Total number of gains: 104; Total number of losses: 35; Total Number of normals: 349.
Somatic mutations of KLRG1:
Generating mutation plots.
Highly correlated genes for KLRG1:
Showing top 20/741 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLRG1 | GIMAP5 | 0.806581 | 3 | 0 | 3 |
| KLRG1 | ARHGAP15 | 0.802302 | 3 | 0 | 3 |
| KLRG1 | KDM5D | 0.795713 | 3 | 0 | 3 |
| KLRG1 | CNTF | 0.773652 | 3 | 0 | 3 |
| KLRG1 | TAGAP | 0.737006 | 4 | 0 | 4 |
| KLRG1 | NOTCH4 | 0.736778 | 4 | 0 | 3 |
| KLRG1 | ITK | 0.729974 | 4 | 0 | 4 |
| KLRG1 | HHLA1 | 0.72812 | 5 | 0 | 5 |
| KLRG1 | EPS8L3 | 0.713506 | 4 | 0 | 4 |
| KLRG1 | HEYL | 0.703755 | 5 | 0 | 5 |
| KLRG1 | CREBL2 | 0.702979 | 4 | 0 | 4 |
| KLRG1 | GPR171 | 0.698763 | 3 | 0 | 3 |
| KLRG1 | FOXC2 | 0.697384 | 3 | 0 | 3 |
| KLRG1 | AMBRA1 | 0.69704 | 3 | 0 | 3 |
| KLRG1 | LINC00474 | 0.696974 | 5 | 0 | 5 |
| KLRG1 | GIMAP6 | 0.694698 | 4 | 0 | 3 |
| KLRG1 | ABHD1 | 0.694595 | 3 | 0 | 3 |
| KLRG1 | APOB | 0.694342 | 5 | 0 | 5 |
| KLRG1 | CORO1A | 0.694199 | 3 | 0 | 3 |
| KLRG1 | ZMAT4 | 0.691169 | 3 | 0 | 3 |
For details and further investigation, click here
