| Full name: hemoglobin subunit theta 1 | Alias Symbol: HBQ | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 3049 | HGNC ID: HGNC:4833 | Ensembl Gene: ENSG00000086506 | OMIM ID: 142240 |
| Drug and gene relationship at DGIdb | |||
Expression of HBQ1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HBQ1 | 3049 | 220807_at | 0.0093 | 0.9770 | |
| GSE20347 | HBQ1 | 3049 | 220807_at | -0.1459 | 0.0344 | |
| GSE23400 | HBQ1 | 3049 | 220807_at | -0.1429 | 0.0036 | |
| GSE26886 | HBQ1 | 3049 | 220807_at | 0.2644 | 0.0067 | |
| GSE29001 | HBQ1 | 3049 | 220807_at | -0.1239 | 0.4626 | |
| GSE38129 | HBQ1 | 3049 | 220807_at | -0.1994 | 0.0011 | |
| GSE45670 | HBQ1 | 3049 | 220807_at | -0.0333 | 0.7731 | |
| GSE53622 | HBQ1 | 3049 | 26908 | -0.8151 | 0.0000 | |
| GSE53624 | HBQ1 | 3049 | 26908 | -0.7065 | 0.0000 | |
| GSE63941 | HBQ1 | 3049 | 220807_at | 0.5134 | 0.3739 | |
| GSE77861 | HBQ1 | 3049 | 220807_at | -0.2175 | 0.1399 | |
| GSE97050 | HBQ1 | 3049 | A_23_P49254 | -0.7843 | 0.2308 | |
| TCGA | HBQ1 | 3049 | RNAseq | 2.7297 | 0.0999 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HBQ1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HBQ1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HBQ1 | 3049 | 5 | 5 | 20 | |
| GSE20123 | HBQ1 | 3049 | 5 | 4 | 21 | |
| GSE43470 | HBQ1 | 3049 | 3 | 7 | 33 | |
| GSE46452 | HBQ1 | 3049 | 38 | 1 | 20 | |
| GSE47630 | HBQ1 | 3049 | 13 | 6 | 21 | |
| GSE54993 | HBQ1 | 3049 | 3 | 5 | 62 | |
| GSE54994 | HBQ1 | 3049 | 4 | 10 | 39 | |
| GSE60625 | HBQ1 | 3049 | 4 | 0 | 7 | |
| GSE74703 | HBQ1 | 3049 | 3 | 5 | 28 | |
| GSE74704 | HBQ1 | 3049 | 3 | 2 | 15 | |
| TCGA | HBQ1 | 3049 | 20 | 15 | 61 |
Total number of gains: 101; Total number of losses: 60; Total Number of normals: 327.
Somatic mutations of HBQ1:
Generating mutation plots.
Highly correlated genes for HBQ1:
Showing top 20/730 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HBQ1 | SLC45A2 | 0.749906 | 3 | 0 | 3 |
| HBQ1 | KSR1 | 0.727017 | 3 | 0 | 3 |
| HBQ1 | BFSP2 | 0.696111 | 5 | 0 | 5 |
| HBQ1 | PAPPA2 | 0.695728 | 3 | 0 | 3 |
| HBQ1 | ARHGAP44 | 0.69356 | 4 | 0 | 4 |
| HBQ1 | DENND6B | 0.685315 | 3 | 0 | 3 |
| HBQ1 | EPS8L3 | 0.685151 | 4 | 0 | 4 |
| HBQ1 | TMPRSS5 | 0.683392 | 5 | 0 | 4 |
| HBQ1 | FBLN7 | 0.680083 | 3 | 0 | 3 |
| HBQ1 | CLCF1 | 0.671247 | 4 | 0 | 4 |
| HBQ1 | GCGR | 0.669803 | 3 | 0 | 3 |
| HBQ1 | ARR3 | 0.669005 | 3 | 0 | 3 |
| HBQ1 | EBF4 | 0.668981 | 3 | 0 | 3 |
| HBQ1 | DCC | 0.667078 | 3 | 0 | 3 |
| HBQ1 | C4BPA | 0.665597 | 3 | 0 | 3 |
| HBQ1 | CLCNKB | 0.664348 | 6 | 0 | 5 |
| HBQ1 | LAT2 | 0.664109 | 3 | 0 | 3 |
| HBQ1 | RUNDC3A | 0.663903 | 3 | 0 | 3 |
| HBQ1 | SYT13 | 0.663014 | 3 | 0 | 3 |
| HBQ1 | NAT2 | 0.660225 | 4 | 0 | 3 |
For details and further investigation, click here
