| Full name: serpin family A member 4 | Alias Symbol: KST|KAL|KLST|kallistatin | ||
| Type: protein-coding gene | Cytoband: 14q32.13 | ||
| Entrez ID: 5267 | HGNC ID: HGNC:8948 | Ensembl Gene: ENSG00000100665 | OMIM ID: 147935 |
| Drug and gene relationship at DGIdb | |||
Expression of SERPINA4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SERPINA4 | 5267 | 213874_at | 0.0097 | 0.9740 | |
| GSE20347 | SERPINA4 | 5267 | 213874_at | -0.0891 | 0.4296 | |
| GSE23400 | SERPINA4 | 5267 | 213874_at | -0.1664 | 0.0008 | |
| GSE26886 | SERPINA4 | 5267 | 213874_at | 0.0408 | 0.8354 | |
| GSE29001 | SERPINA4 | 5267 | 213874_at | -0.3238 | 0.0588 | |
| GSE38129 | SERPINA4 | 5267 | 213874_at | -0.3390 | 0.0378 | |
| GSE45670 | SERPINA4 | 5267 | 213874_at | 0.0571 | 0.6018 | |
| GSE53622 | SERPINA4 | 5267 | 68118 | -0.5210 | 0.0341 | |
| GSE53624 | SERPINA4 | 5267 | 68118 | -0.4640 | 0.0196 | |
| GSE63941 | SERPINA4 | 5267 | 213874_at | 0.1048 | 0.5108 | |
| GSE77861 | SERPINA4 | 5267 | 213874_at | -0.0726 | 0.5800 | |
| TCGA | SERPINA4 | 5267 | RNAseq | -5.2610 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SERPINA4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SERPINA4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SERPINA4 | 5267 | 10 | 4 | 16 | |
| GSE20123 | SERPINA4 | 5267 | 10 | 3 | 17 | |
| GSE43470 | SERPINA4 | 5267 | 7 | 3 | 33 | |
| GSE46452 | SERPINA4 | 5267 | 16 | 3 | 40 | |
| GSE47630 | SERPINA4 | 5267 | 11 | 8 | 21 | |
| GSE54993 | SERPINA4 | 5267 | 3 | 8 | 59 | |
| GSE54994 | SERPINA4 | 5267 | 21 | 4 | 28 | |
| GSE60625 | SERPINA4 | 5267 | 0 | 2 | 9 | |
| GSE74703 | SERPINA4 | 5267 | 6 | 3 | 27 | |
| GSE74704 | SERPINA4 | 5267 | 6 | 3 | 11 | |
| TCGA | SERPINA4 | 5267 | 30 | 20 | 46 |
Total number of gains: 120; Total number of losses: 61; Total Number of normals: 307.
Somatic mutations of SERPINA4:
Generating mutation plots.
Highly correlated genes for SERPINA4:
Showing top 20/1096 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SERPINA4 | FEV | 0.729391 | 6 | 0 | 6 |
| SERPINA4 | IFT122 | 0.721662 | 4 | 0 | 4 |
| SERPINA4 | NXPE4 | 0.713703 | 4 | 0 | 4 |
| SERPINA4 | GK2 | 0.710279 | 3 | 0 | 3 |
| SERPINA4 | EPS8L3 | 0.702453 | 7 | 0 | 6 |
| SERPINA4 | CYP2A7 | 0.701172 | 5 | 0 | 5 |
| SERPINA4 | NPHS2 | 0.694698 | 5 | 0 | 5 |
| SERPINA4 | KHDRBS2 | 0.683934 | 5 | 0 | 5 |
| SERPINA4 | RCVRN | 0.681679 | 6 | 0 | 6 |
| SERPINA4 | KRT35 | 0.680263 | 3 | 0 | 3 |
| SERPINA4 | HRC | 0.679404 | 3 | 0 | 3 |
| SERPINA4 | HHLA1 | 0.676299 | 5 | 0 | 5 |
| SERPINA4 | A4GNT | 0.674905 | 7 | 0 | 7 |
| SERPINA4 | MYO1A | 0.669938 | 6 | 0 | 6 |
| SERPINA4 | PPFIA2 | 0.669405 | 4 | 0 | 4 |
| SERPINA4 | PNMT | 0.667934 | 4 | 0 | 4 |
| SERPINA4 | PEX5L | 0.666972 | 3 | 0 | 3 |
| SERPINA4 | DRD5 | 0.666309 | 5 | 0 | 5 |
| SERPINA4 | PLA2G1B | 0.665623 | 4 | 0 | 3 |
| SERPINA4 | ARMC4 | 0.665098 | 5 | 0 | 4 |
For details and further investigation, click here
