UBQLN4

 

Full name: ubiquilin 4 Alias Symbol: A1U|UBIN
Type: protein-coding gene Cytoband: 1q22
Entrez ID: 56893 HGNC ID: HGNC:1237 Ensembl Gene: ENSG00000160803 OMIM ID: 605440
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of UBQLN4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 UBQLN4 56893 224513_s_at 0.9647 0.0801
GSE20347 UBQLN4 56893 222252_x_at 0.2693 0.1376
GSE23400 UBQLN4 56893 222252_x_at -0.0895 0.1376
GSE26886 UBQLN4 56893 224513_s_at 0.3644 0.0060
GSE29001 UBQLN4 56893 222252_x_at 0.1120 0.5631
GSE38129 UBQLN4 56893 222252_x_at 0.0280 0.8934
GSE45670 UBQLN4 56893 224513_s_at 0.3255 0.0061
GSE63941 UBQLN4 56893 224513_s_at 0.0058 0.9862
GSE77861 UBQLN4 56893 224513_s_at 0.4224 0.0239
GSE97050 UBQLN4 56893 A_33_P3382380 0.2227 0.4678
SRP007169 UBQLN4 56893 RNAseq -0.2797 0.4034
SRP008496 UBQLN4 56893 RNAseq -0.0497 0.8401
SRP064894 UBQLN4 56893 RNAseq 0.4359 0.0420
SRP133303 UBQLN4 56893 RNAseq 0.1046 0.3412
SRP159526 UBQLN4 56893 RNAseq 0.5924 0.0219
SRP193095 UBQLN4 56893 RNAseq 0.3301 0.0034
SRP219564 UBQLN4 56893 RNAseq 0.3350 0.4397
TCGA UBQLN4 56893 RNAseq 0.0744 0.1276

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by UBQLN4 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of UBQLN4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 UBQLN4 56893 14 0 16
GSE20123 UBQLN4 56893 13 0 17
GSE43470 UBQLN4 56893 7 2 34
GSE46452 UBQLN4 56893 2 1 56
GSE47630 UBQLN4 56893 14 0 26
GSE54993 UBQLN4 56893 0 5 65
GSE54994 UBQLN4 56893 16 0 37
GSE60625 UBQLN4 56893 0 0 11
GSE74703 UBQLN4 56893 7 2 27
GSE74704 UBQLN4 56893 6 0 14
TCGA UBQLN4 56893 38 2 56

Total number of gains: 117; Total number of losses: 12; Total Number of normals: 359.  

 

Somatic mutations of UBQLN4:

 

Generating mutation plots.

 

Highly correlated genes for UBQLN4:

 

Showing top 20/997 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
UBQLN4PPP1R16A0.845736303
UBQLN4ACBD60.830204404
UBQLN4DDB10.812506303
UBQLN4KBTBD60.811698303
UBQLN4PDCD50.793716303
UBQLN4ZNF5840.791242303
UBQLN4SAMD10.788645303
UBQLN4NONO0.779893303
UBQLN4PODNL10.779226605
UBQLN4ZNF6110.776666605
UBQLN4GLRX20.776594303
UBQLN4CPT1A0.776593303
UBQLN4POLR1B0.775922908
UBQLN4SP30.770684303
UBQLN4AP3D10.769544303
UBQLN4VANGL20.76954404
UBQLN4ARHGEF150.769229303
UBQLN4ALS20.769137303
UBQLN4PTK20.766706404
UBQLN4TMTC40.766469303

For details and further investigation, click here