| Full name: nucleotide binding protein like | Alias Symbol: FLJ12660|IND1|huInd1 | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 80224 | HGNC ID: HGNC:20278 | Ensembl Gene: ENSG00000151413 | OMIM ID: 613621 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NUBPL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NUBPL | 80224 | 220176_at | 0.7041 | 0.5125 | |
| GSE20347 | NUBPL | 80224 | 220176_at | 0.6773 | 0.0025 | |
| GSE23400 | NUBPL | 80224 | 220176_at | 0.4121 | 0.0000 | |
| GSE26886 | NUBPL | 80224 | 220176_at | 0.4202 | 0.0967 | |
| GSE29001 | NUBPL | 80224 | 220176_at | 0.6000 | 0.1268 | |
| GSE38129 | NUBPL | 80224 | 220176_at | 0.3929 | 0.0512 | |
| GSE45670 | NUBPL | 80224 | 220176_at | 0.1655 | 0.1511 | |
| GSE53622 | NUBPL | 80224 | 69732 | 0.3735 | 0.0000 | |
| GSE53624 | NUBPL | 80224 | 69732 | 0.6066 | 0.0000 | |
| GSE63941 | NUBPL | 80224 | 220176_at | 0.7242 | 0.1683 | |
| GSE77861 | NUBPL | 80224 | 220176_at | 0.0236 | 0.9112 | |
| GSE97050 | NUBPL | 80224 | A_33_P3344733 | -0.0234 | 0.9503 | |
| SRP007169 | NUBPL | 80224 | RNAseq | 2.3340 | 0.0011 | |
| SRP064894 | NUBPL | 80224 | RNAseq | 0.3335 | 0.0243 | |
| SRP133303 | NUBPL | 80224 | RNAseq | 0.6192 | 0.0067 | |
| SRP159526 | NUBPL | 80224 | RNAseq | 0.3962 | 0.1031 | |
| SRP193095 | NUBPL | 80224 | RNAseq | 0.2282 | 0.0134 | |
| SRP219564 | NUBPL | 80224 | RNAseq | 0.0032 | 0.9944 | |
| TCGA | NUBPL | 80224 | RNAseq | -0.0095 | 0.8937 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NUBPL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NUBPL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NUBPL | 80224 | 9 | 4 | 17 | |
| GSE20123 | NUBPL | 80224 | 9 | 4 | 17 | |
| GSE43470 | NUBPL | 80224 | 10 | 2 | 31 | |
| GSE46452 | NUBPL | 80224 | 17 | 2 | 40 | |
| GSE47630 | NUBPL | 80224 | 11 | 10 | 19 | |
| GSE54993 | NUBPL | 80224 | 3 | 11 | 56 | |
| GSE54994 | NUBPL | 80224 | 18 | 5 | 30 | |
| GSE60625 | NUBPL | 80224 | 0 | 2 | 9 | |
| GSE74703 | NUBPL | 80224 | 9 | 2 | 25 | |
| GSE74704 | NUBPL | 80224 | 4 | 3 | 13 | |
| TCGA | NUBPL | 80224 | 34 | 13 | 49 |
Total number of gains: 124; Total number of losses: 58; Total Number of normals: 306.
Somatic mutations of NUBPL:
Generating mutation plots.
Highly correlated genes for NUBPL:
Showing top 20/390 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NUBPL | IL17RD | 0.894347 | 3 | 0 | 3 |
| NUBPL | ERGIC1 | 0.789546 | 3 | 0 | 3 |
| NUBPL | FCGR3A | 0.73749 | 3 | 0 | 3 |
| NUBPL | EGLN2 | 0.717122 | 3 | 0 | 3 |
| NUBPL | KLHL28 | 0.710683 | 4 | 0 | 4 |
| NUBPL | ZNF808 | 0.697442 | 3 | 0 | 3 |
| NUBPL | RALGAPA1 | 0.693791 | 5 | 0 | 5 |
| NUBPL | AGTPBP1 | 0.689194 | 3 | 0 | 3 |
| NUBPL | ZNF669 | 0.68849 | 4 | 0 | 3 |
| NUBPL | ZFP1 | 0.686666 | 3 | 0 | 3 |
| NUBPL | TIGD1 | 0.679235 | 4 | 0 | 3 |
| NUBPL | LIN52 | 0.677909 | 7 | 0 | 5 |
| NUBPL | SLC25A21 | 0.676811 | 4 | 0 | 3 |
| NUBPL | USP14 | 0.659932 | 7 | 0 | 6 |
| NUBPL | ZNF227 | 0.65435 | 5 | 0 | 3 |
| NUBPL | IRF2BPL | 0.651461 | 5 | 0 | 4 |
| NUBPL | RNF139 | 0.649725 | 6 | 0 | 5 |
| NUBPL | MRPS15 | 0.64898 | 4 | 0 | 3 |
| NUBPL | LATS1 | 0.647533 | 3 | 0 | 3 |
| NUBPL | KANSL2 | 0.640214 | 4 | 0 | 4 |
For details and further investigation, click here
