GMEB2

 

Full name: glucocorticoid modulatory element binding protein 2 Alias Symbol: P79PIF|KIAA1269|PIF79
Type: protein-coding gene Cytoband: 20q13.33
Entrez ID: 26205 HGNC ID: HGNC:4371 Ensembl Gene: ENSG00000101216 OMIM ID: 607451
Drug and gene relationship at DGIdb

 

Expression of GMEB2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 GMEB2 26205 44146_at 0.7018 0.1185
GSE20347 GMEB2 26205 44146_at 0.3376 0.0008
GSE23400 GMEB2 26205 44146_at 0.1260 0.0003
GSE26886 GMEB2 26205 44146_at 0.5788 0.0059
GSE29001 GMEB2 26205 44146_at 0.3918 0.0480
GSE38129 GMEB2 26205 44146_at 0.2282 0.0086
GSE45670 GMEB2 26205 44146_at 0.2463 0.0319
GSE53622 GMEB2 26205 42403 0.4144 0.0000
GSE53624 GMEB2 26205 42403 0.6991 0.0000
GSE63941 GMEB2 26205 44146_at 0.1838 0.5637
GSE77861 GMEB2 26205 44146_at 0.2473 0.0535
GSE97050 GMEB2 26205 A_23_P337033 -0.0368 0.9029
SRP007169 GMEB2 26205 RNAseq -0.1176 0.7684
SRP008496 GMEB2 26205 RNAseq -0.2687 0.4491
SRP064894 GMEB2 26205 RNAseq 0.2953 0.0591
SRP133303 GMEB2 26205 RNAseq 0.1032 0.4945
SRP159526 GMEB2 26205 RNAseq 0.2148 0.4085
SRP193095 GMEB2 26205 RNAseq 0.4261 0.0000
SRP219564 GMEB2 26205 RNAseq 0.4499 0.2055
TCGA GMEB2 26205 RNAseq 0.1017 0.0526

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by GMEB2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of GMEB2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 GMEB2 26205 14 2 14
GSE20123 GMEB2 26205 14 2 14
GSE43470 GMEB2 26205 11 1 31
GSE46452 GMEB2 26205 35 0 24
GSE47630 GMEB2 26205 25 1 14
GSE54993 GMEB2 26205 0 17 53
GSE54994 GMEB2 26205 29 0 24
GSE60625 GMEB2 26205 0 0 11
GSE74703 GMEB2 26205 10 0 26
GSE74704 GMEB2 26205 11 0 9
TCGA GMEB2 26205 44 4 48

Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.  


 

Somatic mutations of GMEB2:

 

Generating mutation plots.

 

Highly correlated genes for GMEB2:

 

Showing top 20/1221 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
GMEB2DGCR20.813909404
GMEB2TMEM63B0.805912303
GMEB2ERGIC10.801808303
GMEB2MACF10.786059303
GMEB2SMAD10.77779303
GMEB2PSMB60.770646303
GMEB2INPP5B0.769552303
GMEB2CHD30.764218404
GMEB2DROSHA0.761254403
GMEB2DAPK30.755019303
GMEB2SNAPC20.751996303
GMEB2SLC25A380.750664303
GMEB2CISD20.740382303
GMEB2ATXN1L0.739067303
GMEB2FIP1L10.738444303
GMEB2DOT1L0.738433303
GMEB2SFR10.738248303
GMEB2DGCR80.736064303
GMEB2NAF10.731235404
GMEB2DDX590.730533303

For details and further investigation, click here