| Full name: malectin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 12q24.31 | ||
| Entrez ID: 9761 | HGNC ID: HGNC:28973 | Ensembl Gene: ENSG00000110917 | OMIM ID: 613802 |
| Drug and gene relationship at DGIdb | |||
Expression of MLEC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MLEC | 9761 | 200616_s_at | 1.1784 | 0.1178 | |
| GSE20347 | MLEC | 9761 | 200616_s_at | 0.5691 | 0.0009 | |
| GSE23400 | MLEC | 9761 | 200617_at | 0.2834 | 0.0000 | |
| GSE26886 | MLEC | 9761 | 200616_s_at | 0.9668 | 0.0000 | |
| GSE29001 | MLEC | 9761 | 200616_s_at | 0.8575 | 0.0150 | |
| GSE38129 | MLEC | 9761 | 200616_s_at | 0.6705 | 0.0006 | |
| GSE45670 | MLEC | 9761 | 200616_s_at | 0.5714 | 0.0012 | |
| GSE53622 | MLEC | 9761 | 99538 | 0.4995 | 0.0000 | |
| GSE53624 | MLEC | 9761 | 99538 | 0.5816 | 0.0000 | |
| GSE63941 | MLEC | 9761 | 200616_s_at | -1.2260 | 0.0079 | |
| GSE77861 | MLEC | 9761 | 200617_at | 0.4107 | 0.0139 | |
| GSE97050 | MLEC | 9761 | A_24_P304449 | 0.2056 | 0.4270 | |
| SRP007169 | MLEC | 9761 | RNAseq | 0.8338 | 0.0588 | |
| SRP008496 | MLEC | 9761 | RNAseq | 0.8960 | 0.0001 | |
| SRP064894 | MLEC | 9761 | RNAseq | 0.6811 | 0.0000 | |
| SRP133303 | MLEC | 9761 | RNAseq | 0.5793 | 0.0000 | |
| SRP159526 | MLEC | 9761 | RNAseq | 0.8822 | 0.0000 | |
| SRP193095 | MLEC | 9761 | RNAseq | 0.2698 | 0.1497 | |
| SRP219564 | MLEC | 9761 | RNAseq | 0.4425 | 0.2621 | |
| TCGA | MLEC | 9761 | RNAseq | -0.1808 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MLEC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MLEC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MLEC | 9761 | 6 | 2 | 22 | |
| GSE20123 | MLEC | 9761 | 6 | 2 | 22 | |
| GSE43470 | MLEC | 9761 | 2 | 2 | 39 | |
| GSE46452 | MLEC | 9761 | 9 | 1 | 49 | |
| GSE47630 | MLEC | 9761 | 9 | 3 | 28 | |
| GSE54993 | MLEC | 9761 | 0 | 5 | 65 | |
| GSE54994 | MLEC | 9761 | 7 | 6 | 40 | |
| GSE60625 | MLEC | 9761 | 0 | 0 | 11 | |
| GSE74703 | MLEC | 9761 | 2 | 1 | 33 | |
| GSE74704 | MLEC | 9761 | 3 | 2 | 15 | |
| TCGA | MLEC | 9761 | 20 | 11 | 65 |
Total number of gains: 64; Total number of losses: 35; Total Number of normals: 389.
Somatic mutations of MLEC:
Generating mutation plots.
Highly correlated genes for MLEC:
Showing top 20/1414 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MLEC | SH3RF3 | 0.848486 | 3 | 0 | 3 |
| MLEC | ZNF584 | 0.839606 | 3 | 0 | 3 |
| MLEC | OTUD6B | 0.830567 | 3 | 0 | 3 |
| MLEC | DCAF16 | 0.82851 | 3 | 0 | 3 |
| MLEC | SLC39A3 | 0.819277 | 4 | 0 | 4 |
| MLEC | ERGIC1 | 0.808894 | 3 | 0 | 3 |
| MLEC | CRTC2 | 0.791063 | 4 | 0 | 4 |
| MLEC | ZNF71 | 0.789438 | 3 | 0 | 3 |
| MLEC | RPGR | 0.775902 | 3 | 0 | 3 |
| MLEC | PACS1 | 0.761848 | 3 | 0 | 3 |
| MLEC | TOMM40L | 0.758163 | 3 | 0 | 3 |
| MLEC | RNF4 | 0.756101 | 3 | 0 | 3 |
| MLEC | KRTCAP2 | 0.753783 | 5 | 0 | 5 |
| MLEC | RILPL1 | 0.734799 | 3 | 0 | 3 |
| MLEC | ABHD16A | 0.730791 | 3 | 0 | 3 |
| MLEC | DYRK2 | 0.725202 | 4 | 0 | 3 |
| MLEC | GNPNAT1 | 0.723223 | 3 | 0 | 3 |
| MLEC | CD99L2 | 0.718461 | 3 | 0 | 3 |
| MLEC | RGL1 | 0.708374 | 4 | 0 | 4 |
| MLEC | RAB2B | 0.705498 | 3 | 0 | 3 |
For details and further investigation, click here
