| Full name: sprouty related EVH1 domain containing 1 | Alias Symbol: FLJ33903|PPP1R147 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 161742 | HGNC ID: HGNC:20249 | Ensembl Gene: ENSG00000166068 | OMIM ID: 609291 |
| Drug and gene relationship at DGIdb | |||
Expression of SPRED1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRED1 | 161742 | 226837_at | 0.4500 | 0.3997 | |
| GSE26886 | SPRED1 | 161742 | 235074_at | 0.7620 | 0.0020 | |
| GSE45670 | SPRED1 | 161742 | 226837_at | -0.2221 | 0.3956 | |
| GSE53622 | SPRED1 | 161742 | 8898 | 0.5162 | 0.0000 | |
| GSE53624 | SPRED1 | 161742 | 8898 | 0.5937 | 0.0000 | |
| GSE63941 | SPRED1 | 161742 | 226837_at | -1.8636 | 0.0507 | |
| GSE77861 | SPRED1 | 161742 | 226837_at | 1.0383 | 0.0083 | |
| GSE97050 | SPRED1 | 161742 | A_24_P107859 | 0.2158 | 0.4169 | |
| SRP007169 | SPRED1 | 161742 | RNAseq | 1.7733 | 0.0000 | |
| SRP008496 | SPRED1 | 161742 | RNAseq | 1.8688 | 0.0000 | |
| SRP064894 | SPRED1 | 161742 | RNAseq | 0.4124 | 0.1315 | |
| SRP133303 | SPRED1 | 161742 | RNAseq | 0.9057 | 0.0000 | |
| SRP159526 | SPRED1 | 161742 | RNAseq | 0.5124 | 0.0074 | |
| SRP193095 | SPRED1 | 161742 | RNAseq | 0.2674 | 0.1086 | |
| SRP219564 | SPRED1 | 161742 | RNAseq | 0.1090 | 0.7683 | |
| TCGA | SPRED1 | 161742 | RNAseq | -0.0572 | 0.3236 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SPRED1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRED1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRED1 | 161742 | 2 | 6 | 22 | |
| GSE20123 | SPRED1 | 161742 | 3 | 6 | 21 | |
| GSE43470 | SPRED1 | 161742 | 4 | 5 | 34 | |
| GSE46452 | SPRED1 | 161742 | 3 | 7 | 49 | |
| GSE47630 | SPRED1 | 161742 | 8 | 11 | 21 | |
| GSE54993 | SPRED1 | 161742 | 4 | 6 | 60 | |
| GSE54994 | SPRED1 | 161742 | 5 | 7 | 41 | |
| GSE60625 | SPRED1 | 161742 | 4 | 0 | 7 | |
| GSE74703 | SPRED1 | 161742 | 4 | 4 | 28 | |
| GSE74704 | SPRED1 | 161742 | 1 | 5 | 14 | |
| TCGA | SPRED1 | 161742 | 11 | 18 | 67 |
Total number of gains: 49; Total number of losses: 75; Total Number of normals: 364.
Somatic mutations of SPRED1:
Generating mutation plots.
Highly correlated genes for SPRED1:
Showing top 20/1132 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRED1 | HSF2 | 0.881653 | 3 | 0 | 3 |
| SPRED1 | DHX40 | 0.826454 | 3 | 0 | 3 |
| SPRED1 | U2SURP | 0.817707 | 3 | 0 | 3 |
| SPRED1 | RPL26L1 | 0.806147 | 3 | 0 | 3 |
| SPRED1 | GCLC | 0.788523 | 3 | 0 | 3 |
| SPRED1 | RICTOR | 0.788021 | 3 | 0 | 3 |
| SPRED1 | HMGA2 | 0.785434 | 3 | 0 | 3 |
| SPRED1 | HAS3 | 0.782748 | 3 | 0 | 3 |
| SPRED1 | CALCRL | 0.778872 | 3 | 0 | 3 |
| SPRED1 | INTS10 | 0.772763 | 3 | 0 | 3 |
| SPRED1 | STAT2 | 0.771846 | 3 | 0 | 3 |
| SPRED1 | ESF1 | 0.767285 | 3 | 0 | 3 |
| SPRED1 | ZNF121 | 0.762326 | 3 | 0 | 3 |
| SPRED1 | SLFN12 | 0.760885 | 3 | 0 | 3 |
| SPRED1 | WDR81 | 0.756959 | 3 | 0 | 3 |
| SPRED1 | LRRC59 | 0.75256 | 4 | 0 | 4 |
| SPRED1 | WIPI1 | 0.751931 | 3 | 0 | 3 |
| SPRED1 | NME1 | 0.749614 | 3 | 0 | 3 |
| SPRED1 | PTPRZ1 | 0.746787 | 4 | 0 | 4 |
| SPRED1 | CXCL3 | 0.743669 | 4 | 0 | 3 |
For details and further investigation, click here
