| Full name: KIAA0586 | Alias Symbol: Talpid3|JBTS23 | ||
| Type: protein-coding gene | Cytoband: 14q23.1 | ||
| Entrez ID: 9786 | HGNC ID: HGNC:19960 | Ensembl Gene: ENSG00000100578 | OMIM ID: 610178 |
| Drug and gene relationship at DGIdb | |||
Expression of KIAA0586:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIAA0586 | 9786 | 205631_at | 0.4162 | 0.2147 | |
| GSE20347 | KIAA0586 | 9786 | 205631_at | -0.0039 | 0.9744 | |
| GSE23400 | KIAA0586 | 9786 | 205631_at | -0.0463 | 0.3498 | |
| GSE26886 | KIAA0586 | 9786 | 205631_at | 0.2410 | 0.1129 | |
| GSE29001 | KIAA0586 | 9786 | 205631_at | 0.1498 | 0.4646 | |
| GSE38129 | KIAA0586 | 9786 | 205631_at | -0.0026 | 0.9822 | |
| GSE45670 | KIAA0586 | 9786 | 205631_at | 0.1591 | 0.1799 | |
| GSE53622 | KIAA0586 | 9786 | 59698 | -0.0847 | 0.4263 | |
| GSE53624 | KIAA0586 | 9786 | 59698 | 0.2835 | 0.0000 | |
| GSE63941 | KIAA0586 | 9786 | 205631_at | 0.2027 | 0.6539 | |
| GSE77861 | KIAA0586 | 9786 | 205631_at | 0.0375 | 0.8648 | |
| GSE97050 | KIAA0586 | 9786 | A_23_P106127 | 0.1935 | 0.6204 | |
| SRP007169 | KIAA0586 | 9786 | RNAseq | 0.5747 | 0.1394 | |
| SRP008496 | KIAA0586 | 9786 | RNAseq | 0.3660 | 0.1643 | |
| SRP064894 | KIAA0586 | 9786 | RNAseq | 0.1334 | 0.5108 | |
| SRP133303 | KIAA0586 | 9786 | RNAseq | 0.0231 | 0.8721 | |
| SRP159526 | KIAA0586 | 9786 | RNAseq | -0.2248 | 0.2639 | |
| SRP193095 | KIAA0586 | 9786 | RNAseq | 0.0111 | 0.9027 | |
| SRP219564 | KIAA0586 | 9786 | RNAseq | 0.1239 | 0.6720 | |
| TCGA | KIAA0586 | 9786 | RNAseq | 0.0944 | 0.1318 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIAA0586 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIAA0586:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIAA0586 | 9786 | 8 | 3 | 19 | |
| GSE20123 | KIAA0586 | 9786 | 7 | 3 | 20 | |
| GSE43470 | KIAA0586 | 9786 | 8 | 2 | 33 | |
| GSE46452 | KIAA0586 | 9786 | 16 | 3 | 40 | |
| GSE47630 | KIAA0586 | 9786 | 11 | 10 | 19 | |
| GSE54993 | KIAA0586 | 9786 | 3 | 8 | 59 | |
| GSE54994 | KIAA0586 | 9786 | 19 | 4 | 30 | |
| GSE60625 | KIAA0586 | 9786 | 0 | 2 | 9 | |
| GSE74703 | KIAA0586 | 9786 | 7 | 2 | 27 | |
| GSE74704 | KIAA0586 | 9786 | 3 | 2 | 15 | |
| TCGA | KIAA0586 | 9786 | 32 | 15 | 49 |
Total number of gains: 114; Total number of losses: 54; Total Number of normals: 320.
Somatic mutations of KIAA0586:
Generating mutation plots.
Highly correlated genes for KIAA0586:
Showing top 20/433 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIAA0586 | ESF1 | 0.835378 | 3 | 0 | 3 |
| KIAA0586 | EBAG9 | 0.763721 | 3 | 0 | 3 |
| KIAA0586 | PSMB7 | 0.760549 | 3 | 0 | 3 |
| KIAA0586 | DNAJC2 | 0.753275 | 3 | 0 | 3 |
| KIAA0586 | YWHAG | 0.74148 | 3 | 0 | 3 |
| KIAA0586 | BAK1 | 0.740711 | 3 | 0 | 3 |
| KIAA0586 | FDPS | 0.738678 | 3 | 0 | 3 |
| KIAA0586 | CDK8 | 0.735114 | 3 | 0 | 3 |
| KIAA0586 | EIF5B | 0.734378 | 3 | 0 | 3 |
| KIAA0586 | WDR5 | 0.733557 | 3 | 0 | 3 |
| KIAA0586 | RIOK1 | 0.730888 | 3 | 0 | 3 |
| KIAA0586 | ISY1 | 0.716882 | 3 | 0 | 3 |
| KIAA0586 | CNOT2 | 0.715109 | 3 | 0 | 3 |
| KIAA0586 | ATXN1 | 0.714193 | 3 | 0 | 3 |
| KIAA0586 | IRF2BPL | 0.712743 | 3 | 0 | 3 |
| KIAA0586 | SRFBP1 | 0.710929 | 3 | 0 | 3 |
| KIAA0586 | BET1 | 0.704647 | 3 | 0 | 3 |
| KIAA0586 | RPL8 | 0.702055 | 3 | 0 | 3 |
| KIAA0586 | BAG4 | 0.701466 | 3 | 0 | 3 |
| KIAA0586 | MAP4K4 | 0.697026 | 4 | 0 | 4 |
For details and further investigation, click here
