| Full name: centriolar coiled-coil protein 110 | Alias Symbol: KIAA0419|CP110 | ||
| Type: protein-coding gene | Cytoband: 16p12.3 | ||
| Entrez ID: 9738 | HGNC ID: HGNC:24342 | Ensembl Gene: ENSG00000103540 | OMIM ID: 609544 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CCP110:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CCP110 | 9738 | 204662_at | 0.4395 | 0.2324 | |
| GSE20347 | CCP110 | 9738 | 204662_at | 0.4247 | 0.0050 | |
| GSE23400 | CCP110 | 9738 | 204662_at | 0.1495 | 0.0007 | |
| GSE26886 | CCP110 | 9738 | 204662_at | 0.2586 | 0.1159 | |
| GSE29001 | CCP110 | 9738 | 204662_at | 0.3763 | 0.1689 | |
| GSE38129 | CCP110 | 9738 | 204662_at | 0.3847 | 0.0155 | |
| GSE45670 | CCP110 | 9738 | 204662_at | 0.0144 | 0.9593 | |
| GSE53622 | CCP110 | 9738 | 155299 | 0.1126 | 0.2764 | |
| GSE53624 | CCP110 | 9738 | 155299 | 0.4249 | 0.0000 | |
| GSE63941 | CCP110 | 9738 | 204662_at | 0.5534 | 0.2164 | |
| GSE77861 | CCP110 | 9738 | 204662_at | 0.1921 | 0.3002 | |
| GSE97050 | CCP110 | 9738 | A_24_P373286 | 0.1638 | 0.6078 | |
| SRP007169 | CCP110 | 9738 | RNAseq | 2.6676 | 0.0000 | |
| SRP008496 | CCP110 | 9738 | RNAseq | 2.6818 | 0.0000 | |
| SRP064894 | CCP110 | 9738 | RNAseq | -0.0721 | 0.7718 | |
| SRP133303 | CCP110 | 9738 | RNAseq | 0.3788 | 0.0235 | |
| SRP159526 | CCP110 | 9738 | RNAseq | 0.2403 | 0.3408 | |
| SRP193095 | CCP110 | 9738 | RNAseq | 0.2904 | 0.0002 | |
| SRP219564 | CCP110 | 9738 | RNAseq | -0.1343 | 0.7485 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by CCP110 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of CCP110:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CCP110 | 9738 | 6 | 3 | 21 | |
| GSE20123 | CCP110 | 9738 | 6 | 2 | 22 | |
| GSE43470 | CCP110 | 9738 | 3 | 3 | 37 | |
| GSE46452 | CCP110 | 9738 | 38 | 1 | 20 | |
| GSE47630 | CCP110 | 9738 | 11 | 6 | 23 | |
| GSE54993 | CCP110 | 9738 | 3 | 5 | 62 | |
| GSE54994 | CCP110 | 9738 | 3 | 10 | 40 | |
| GSE60625 | CCP110 | 9738 | 4 | 0 | 7 | |
| GSE74703 | CCP110 | 9738 | 3 | 2 | 31 | |
| GSE74704 | CCP110 | 9738 | 3 | 1 | 16 | |
| TCGA | CCP110 | 9738 | 21 | 12 | 63 |
Total number of gains: 101; Total number of losses: 45; Total Number of normals: 342.
Somatic mutations of CCP110:
Generating mutation plots.
Highly correlated genes for CCP110:
Showing top 20/927 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CCP110 | ESF1 | 0.808836 | 3 | 0 | 3 |
| CCP110 | BLCAP | 0.774624 | 3 | 0 | 3 |
| CCP110 | PPIL4 | 0.764367 | 3 | 0 | 3 |
| CCP110 | PPIL1 | 0.749356 | 4 | 0 | 4 |
| CCP110 | OTUD6B | 0.745043 | 3 | 0 | 3 |
| CCP110 | BAG4 | 0.738325 | 3 | 0 | 3 |
| CCP110 | CENPBD1 | 0.735172 | 3 | 0 | 3 |
| CCP110 | MATR3 | 0.729688 | 3 | 0 | 3 |
| CCP110 | FAM160B1 | 0.726196 | 3 | 0 | 3 |
| CCP110 | KLHL21 | 0.724506 | 3 | 0 | 3 |
| CCP110 | CYB5D1 | 0.722972 | 3 | 0 | 3 |
| CCP110 | RBMS1 | 0.722875 | 3 | 0 | 3 |
| CCP110 | LINC00328 | 0.722788 | 3 | 0 | 3 |
| CCP110 | RPUSD4 | 0.721945 | 3 | 0 | 3 |
| CCP110 | MTO1 | 0.717326 | 5 | 0 | 5 |
| CCP110 | DNTTIP1 | 0.716315 | 4 | 0 | 3 |
| CCP110 | KBTBD6 | 0.715985 | 5 | 0 | 4 |
| CCP110 | MRPS34 | 0.715813 | 3 | 0 | 3 |
| CCP110 | NSMCE2 | 0.714693 | 3 | 0 | 3 |
| CCP110 | GLIPR1 | 0.706657 | 3 | 0 | 3 |
For details and further investigation, click here
