| Full name: DEAH-box helicase 33 | Alias Symbol: FLJ21972|DKFZp762F2011 | ||
| Type: protein-coding gene | Cytoband: 17p13.2 | ||
| Entrez ID: 56919 | HGNC ID: HGNC:16718 | Ensembl Gene: ENSG00000005100 | OMIM ID: 614405 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DHX33:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DHX33 | 56919 | 222875_at | 0.8897 | 0.0138 | |
| GSE26886 | DHX33 | 56919 | 222875_at | 0.5167 | 0.0528 | |
| GSE45670 | DHX33 | 56919 | 222875_at | 0.4418 | 0.0180 | |
| GSE53622 | DHX33 | 56919 | 51468 | 0.8782 | 0.0000 | |
| GSE53624 | DHX33 | 56919 | 51468 | 0.8427 | 0.0000 | |
| GSE63941 | DHX33 | 56919 | 222875_at | 1.3734 | 0.0159 | |
| GSE77861 | DHX33 | 56919 | 222875_at | 0.9503 | 0.0126 | |
| GSE97050 | DHX33 | 56919 | A_24_P364970 | 0.5005 | 0.1399 | |
| SRP007169 | DHX33 | 56919 | RNAseq | 2.4666 | 0.0001 | |
| SRP008496 | DHX33 | 56919 | RNAseq | 2.4618 | 0.0000 | |
| SRP064894 | DHX33 | 56919 | RNAseq | 0.4526 | 0.0063 | |
| SRP133303 | DHX33 | 56919 | RNAseq | 0.4784 | 0.0003 | |
| SRP159526 | DHX33 | 56919 | RNAseq | 0.8181 | 0.0000 | |
| SRP193095 | DHX33 | 56919 | RNAseq | 0.6831 | 0.0000 | |
| SRP219564 | DHX33 | 56919 | RNAseq | 0.7559 | 0.0841 | |
| TCGA | DHX33 | 56919 | RNAseq | 0.1403 | 0.0465 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by DHX33 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DHX33:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DHX33 | 56919 | 5 | 2 | 23 | |
| GSE20123 | DHX33 | 56919 | 5 | 3 | 22 | |
| GSE43470 | DHX33 | 56919 | 1 | 6 | 36 | |
| GSE46452 | DHX33 | 56919 | 34 | 1 | 24 | |
| GSE47630 | DHX33 | 56919 | 7 | 1 | 32 | |
| GSE54993 | DHX33 | 56919 | 4 | 3 | 63 | |
| GSE54994 | DHX33 | 56919 | 5 | 8 | 40 | |
| GSE60625 | DHX33 | 56919 | 4 | 0 | 7 | |
| GSE74703 | DHX33 | 56919 | 1 | 3 | 32 | |
| GSE74704 | DHX33 | 56919 | 3 | 1 | 16 | |
| TCGA | DHX33 | 56919 | 18 | 20 | 58 |
Total number of gains: 87; Total number of losses: 48; Total Number of normals: 353.
Somatic mutations of DHX33:
Generating mutation plots.
Highly correlated genes for DHX33:
Showing top 20/1983 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DHX33 | CIAO1 | 0.841 | 3 | 0 | 3 |
| DHX33 | MMS22L | 0.799742 | 3 | 0 | 3 |
| DHX33 | CBL | 0.794416 | 3 | 0 | 3 |
| DHX33 | HHEX | 0.785963 | 3 | 0 | 3 |
| DHX33 | ZZZ3 | 0.782347 | 3 | 0 | 3 |
| DHX33 | UBE2O | 0.781194 | 4 | 0 | 4 |
| DHX33 | UCK2 | 0.770253 | 3 | 0 | 3 |
| DHX33 | KTI12 | 0.769699 | 3 | 0 | 3 |
| DHX33 | ZDHHC17 | 0.766737 | 3 | 0 | 3 |
| DHX33 | TMEM97 | 0.763127 | 7 | 0 | 7 |
| DHX33 | PTDSS1 | 0.76042 | 6 | 0 | 6 |
| DHX33 | PIGS | 0.759158 | 3 | 0 | 3 |
| DHX33 | ALG1 | 0.757272 | 3 | 0 | 3 |
| DHX33 | CCNE1 | 0.757204 | 4 | 0 | 4 |
| DHX33 | PET117 | 0.750594 | 4 | 0 | 4 |
| DHX33 | ZNF680 | 0.7495 | 3 | 0 | 3 |
| DHX33 | SRRT | 0.748778 | 6 | 0 | 6 |
| DHX33 | DSCC1 | 0.748239 | 5 | 0 | 4 |
| DHX33 | ZNF707 | 0.747694 | 3 | 0 | 3 |
| DHX33 | R3HDM2 | 0.747496 | 3 | 0 | 3 |
For details and further investigation, click here
