| Full name: thioredoxin related transmembrane protein 3 | Alias Symbol: FLJ20793|KIAA1830|PDIA13 | ||
| Type: protein-coding gene | Cytoband: 18q22 | ||
| Entrez ID: 54495 | HGNC ID: HGNC:24718 | Ensembl Gene: ENSG00000166479 | OMIM ID: 616102 |
| Drug and gene relationship at DGIdb | |||
Expression of TMX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMX3 | 54495 | 225302_at | -0.0560 | 0.9214 | |
| GSE26886 | TMX3 | 54495 | 225302_at | -0.7559 | 0.0249 | |
| GSE45670 | TMX3 | 54495 | 225302_at | -0.2072 | 0.2489 | |
| GSE53622 | TMX3 | 54495 | 17688 | -0.3350 | 0.0000 | |
| GSE53624 | TMX3 | 54495 | 17688 | -0.1468 | 0.0441 | |
| GSE63941 | TMX3 | 54495 | 225302_at | -3.0387 | 0.0003 | |
| GSE77861 | TMX3 | 54495 | 225302_at | 0.2747 | 0.3305 | |
| GSE97050 | TMX3 | 54495 | A_33_P3252141 | -0.2484 | 0.3225 | |
| SRP007169 | TMX3 | 54495 | RNAseq | -0.0678 | 0.8361 | |
| SRP008496 | TMX3 | 54495 | RNAseq | 0.1444 | 0.4869 | |
| SRP064894 | TMX3 | 54495 | RNAseq | 0.4469 | 0.0610 | |
| SRP133303 | TMX3 | 54495 | RNAseq | 0.3111 | 0.0879 | |
| SRP159526 | TMX3 | 54495 | RNAseq | 0.1026 | 0.7416 | |
| SRP193095 | TMX3 | 54495 | RNAseq | 0.0168 | 0.8727 | |
| SRP219564 | TMX3 | 54495 | RNAseq | -0.1921 | 0.4743 | |
| TCGA | TMX3 | 54495 | RNAseq | -0.0271 | 0.6132 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMX3 | 54495 | 0 | 10 | 20 | |
| GSE20123 | TMX3 | 54495 | 0 | 10 | 20 | |
| GSE43470 | TMX3 | 54495 | 0 | 8 | 35 | |
| GSE46452 | TMX3 | 54495 | 1 | 26 | 32 | |
| GSE47630 | TMX3 | 54495 | 5 | 21 | 14 | |
| GSE54993 | TMX3 | 54495 | 9 | 0 | 61 | |
| GSE54994 | TMX3 | 54495 | 1 | 18 | 34 | |
| GSE60625 | TMX3 | 54495 | 0 | 4 | 7 | |
| GSE74703 | TMX3 | 54495 | 0 | 8 | 28 | |
| GSE74704 | TMX3 | 54495 | 0 | 8 | 12 | |
| TCGA | TMX3 | 54495 | 6 | 47 | 43 |
Total number of gains: 22; Total number of losses: 160; Total Number of normals: 306.
Somatic mutations of TMX3:
Generating mutation plots.
Highly correlated genes for TMX3:
Showing top 20/439 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMX3 | DPH5 | 0.80051 | 3 | 0 | 3 |
| TMX3 | DPP4 | 0.794237 | 3 | 0 | 3 |
| TMX3 | HAUS1 | 0.790322 | 3 | 0 | 3 |
| TMX3 | ZNF322 | 0.773048 | 3 | 0 | 3 |
| TMX3 | GLS | 0.772119 | 3 | 0 | 3 |
| TMX3 | SS18 | 0.76387 | 3 | 0 | 3 |
| TMX3 | BIRC2 | 0.762015 | 3 | 0 | 3 |
| TMX3 | KLF7 | 0.76179 | 3 | 0 | 3 |
| TMX3 | EEA1 | 0.757462 | 3 | 0 | 3 |
| TMX3 | CHMP5 | 0.756089 | 3 | 0 | 3 |
| TMX3 | TYW3 | 0.751061 | 3 | 0 | 3 |
| TMX3 | KIAA1143 | 0.749589 | 3 | 0 | 3 |
| TMX3 | ENTPD4 | 0.739247 | 3 | 0 | 3 |
| TMX3 | WASL | 0.73865 | 3 | 0 | 3 |
| TMX3 | PDGFRB | 0.738395 | 3 | 0 | 3 |
| TMX3 | CHN1 | 0.735433 | 3 | 0 | 3 |
| TMX3 | LRRC17 | 0.735201 | 3 | 0 | 3 |
| TMX3 | ANPEP | 0.729896 | 3 | 0 | 3 |
| TMX3 | HOOK3 | 0.72793 | 4 | 0 | 4 |
| TMX3 | ESF1 | 0.726329 | 3 | 0 | 3 |
For details and further investigation, click here
