| Full name: Kin17 DNA and RNA binding protein | Alias Symbol: KIN17|Rts2 | ||
| Type: protein-coding gene | Cytoband: 10p14 | ||
| Entrez ID: 22944 | HGNC ID: HGNC:6327 | Ensembl Gene: ENSG00000151657 | OMIM ID: 601720 |
| Drug and gene relationship at DGIdb | |||
Expression of KIN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KIN | 22944 | 205664_at | 0.0765 | 0.8977 | |
| GSE20347 | KIN | 22944 | 205664_at | -0.0561 | 0.7732 | |
| GSE23400 | KIN | 22944 | 205664_at | 0.2386 | 0.0034 | |
| GSE26886 | KIN | 22944 | 205664_at | 0.1910 | 0.5506 | |
| GSE29001 | KIN | 22944 | 205664_at | 0.0988 | 0.8210 | |
| GSE38129 | KIN | 22944 | 205664_at | 0.0542 | 0.7026 | |
| GSE45670 | KIN | 22944 | 205664_at | 0.2111 | 0.1293 | |
| GSE53622 | KIN | 22944 | 12840 | -0.1315 | 0.0548 | |
| GSE53624 | KIN | 22944 | 12840 | -0.0185 | 0.8127 | |
| GSE63941 | KIN | 22944 | 205664_at | -0.6502 | 0.1168 | |
| GSE77861 | KIN | 22944 | 205664_at | -0.1253 | 0.6285 | |
| GSE97050 | KIN | 22944 | A_24_P317874 | -0.1061 | 0.6253 | |
| SRP007169 | KIN | 22944 | RNAseq | 0.5930 | 0.3344 | |
| SRP064894 | KIN | 22944 | RNAseq | -0.0596 | 0.6406 | |
| SRP133303 | KIN | 22944 | RNAseq | -0.0337 | 0.7426 | |
| SRP159526 | KIN | 22944 | RNAseq | -0.3761 | 0.1005 | |
| SRP193095 | KIN | 22944 | RNAseq | -0.1264 | 0.1298 | |
| SRP219564 | KIN | 22944 | RNAseq | -0.2367 | 0.3217 | |
| TCGA | KIN | 22944 | RNAseq | 0.0240 | 0.7419 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KIN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KIN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KIN | 22944 | 4 | 8 | 18 | |
| GSE20123 | KIN | 22944 | 4 | 7 | 19 | |
| GSE43470 | KIN | 22944 | 3 | 6 | 34 | |
| GSE46452 | KIN | 22944 | 2 | 14 | 43 | |
| GSE47630 | KIN | 22944 | 5 | 15 | 20 | |
| GSE54993 | KIN | 22944 | 11 | 0 | 59 | |
| GSE54994 | KIN | 22944 | 4 | 10 | 39 | |
| GSE60625 | KIN | 22944 | 0 | 0 | 11 | |
| GSE74703 | KIN | 22944 | 2 | 4 | 30 | |
| GSE74704 | KIN | 22944 | 1 | 6 | 13 | |
| TCGA | KIN | 22944 | 19 | 26 | 51 |
Total number of gains: 55; Total number of losses: 96; Total Number of normals: 337.
Somatic mutations of KIN:
Generating mutation plots.
Highly correlated genes for KIN:
Showing top 20/334 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KIN | SPTY2D1 | 0.790766 | 3 | 0 | 3 |
| KIN | OSBPL2 | 0.778968 | 3 | 0 | 3 |
| KIN | PSMB7 | 0.771563 | 3 | 0 | 3 |
| KIN | SKAP2 | 0.762431 | 3 | 0 | 3 |
| KIN | ESF1 | 0.757537 | 3 | 0 | 3 |
| KIN | NAPG | 0.753905 | 3 | 0 | 3 |
| KIN | PPHLN1 | 0.750873 | 3 | 0 | 3 |
| KIN | SNRNP200 | 0.737384 | 3 | 0 | 3 |
| KIN | NUDT9 | 0.736326 | 4 | 0 | 4 |
| KIN | CTTNBP2NL | 0.736162 | 3 | 0 | 3 |
| KIN | CHIC1 | 0.731839 | 3 | 0 | 3 |
| KIN | CETN2 | 0.731414 | 3 | 0 | 3 |
| KIN | GNG12 | 0.716944 | 3 | 0 | 3 |
| KIN | TRMT12 | 0.716688 | 3 | 0 | 3 |
| KIN | EXOC8 | 0.714506 | 3 | 0 | 3 |
| KIN | PTPN21 | 0.712629 | 3 | 0 | 3 |
| KIN | SCOC | 0.712266 | 3 | 0 | 3 |
| KIN | MKKS | 0.709714 | 3 | 0 | 3 |
| KIN | TBC1D23 | 0.707277 | 4 | 0 | 3 |
| KIN | CNOT6 | 0.707095 | 4 | 0 | 3 |
For details and further investigation, click here
