| Full name: estrogen related receptor alpha | Alias Symbol: ERR1|ERRalpha|NR3B1|ERRa | ||
| Type: protein-coding gene | Cytoband: 11q13.1 | ||
| Entrez ID: 2101 | HGNC ID: HGNC:3471 | Ensembl Gene: ENSG00000173153 | OMIM ID: 601998 |
| Drug and gene relationship at DGIdb | |||
Expression of ESRRA:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESRRA | 2101 | 1487_at | 0.3959 | 0.2928 | |
| GSE20347 | ESRRA | 2101 | 1487_at | -0.0674 | 0.7077 | |
| GSE23400 | ESRRA | 2101 | 1487_at | -0.0819 | 0.0733 | |
| GSE26886 | ESRRA | 2101 | 1487_at | -0.2658 | 0.3154 | |
| GSE29001 | ESRRA | 2101 | 1487_at | -0.2731 | 0.2654 | |
| GSE38129 | ESRRA | 2101 | 1487_at | -0.1477 | 0.3587 | |
| GSE45670 | ESRRA | 2101 | 1487_at | 0.2660 | 0.0200 | |
| GSE53622 | ESRRA | 2101 | 54804 | -0.3303 | 0.0000 | |
| GSE53624 | ESRRA | 2101 | 54804 | -0.2304 | 0.0002 | |
| GSE63941 | ESRRA | 2101 | 1487_at | 0.8651 | 0.0607 | |
| GSE77861 | ESRRA | 2101 | 1487_at | -0.0858 | 0.6135 | |
| GSE97050 | ESRRA | 2101 | A_33_P3243544 | 0.0296 | 0.9301 | |
| SRP007169 | ESRRA | 2101 | RNAseq | -1.0188 | 0.0030 | |
| SRP008496 | ESRRA | 2101 | RNAseq | -0.9711 | 0.0001 | |
| SRP064894 | ESRRA | 2101 | RNAseq | -0.4264 | 0.0186 | |
| SRP133303 | ESRRA | 2101 | RNAseq | -0.2550 | 0.2959 | |
| SRP159526 | ESRRA | 2101 | RNAseq | -0.5566 | 0.0430 | |
| SRP193095 | ESRRA | 2101 | RNAseq | -0.4804 | 0.0015 | |
| SRP219564 | ESRRA | 2101 | RNAseq | -0.4714 | 0.0574 | |
| TCGA | ESRRA | 2101 | RNAseq | -0.1305 | 0.0148 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ESRRA expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESRRA:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESRRA | 2101 | 6 | 5 | 19 | |
| GSE20123 | ESRRA | 2101 | 6 | 5 | 19 | |
| GSE43470 | ESRRA | 2101 | 1 | 3 | 39 | |
| GSE46452 | ESRRA | 2101 | 8 | 4 | 47 | |
| GSE47630 | ESRRA | 2101 | 4 | 6 | 30 | |
| GSE54993 | ESRRA | 2101 | 3 | 0 | 67 | |
| GSE54994 | ESRRA | 2101 | 5 | 5 | 43 | |
| GSE60625 | ESRRA | 2101 | 0 | 4 | 7 | |
| GSE74703 | ESRRA | 2101 | 1 | 1 | 34 | |
| GSE74704 | ESRRA | 2101 | 4 | 3 | 13 | |
| TCGA | ESRRA | 2101 | 21 | 9 | 66 |
Total number of gains: 59; Total number of losses: 45; Total Number of normals: 384.
Somatic mutations of ESRRA:
Generating mutation plots.
Highly correlated genes for ESRRA:
Showing top 20/268 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESRRA | MFSD2B | 0.751567 | 3 | 0 | 3 |
| ESRRA | TRIM11 | 0.730294 | 3 | 0 | 3 |
| ESRRA | FBRSL1 | 0.729753 | 3 | 0 | 3 |
| ESRRA | CLSTN3 | 0.727265 | 3 | 0 | 3 |
| ESRRA | DCD | 0.717667 | 3 | 0 | 3 |
| ESRRA | TMEM102 | 0.715148 | 3 | 0 | 3 |
| ESRRA | LCORL | 0.702559 | 3 | 0 | 3 |
| ESRRA | KBTBD13 | 0.701037 | 3 | 0 | 3 |
| ESRRA | CLEC18C | 0.690721 | 3 | 0 | 3 |
| ESRRA | TPRX1 | 0.69034 | 3 | 0 | 3 |
| ESRRA | SRD5A2 | 0.676149 | 3 | 0 | 3 |
| ESRRA | CD164L2 | 0.674444 | 3 | 0 | 3 |
| ESRRA | OR2Z1 | 0.67244 | 3 | 0 | 3 |
| ESRRA | LRFN2 | 0.666135 | 3 | 0 | 3 |
| ESRRA | KRTAP20-1 | 0.663406 | 3 | 0 | 3 |
| ESRRA | MARVELD3 | 0.6615 | 4 | 0 | 3 |
| ESRRA | MAT1A | 0.661488 | 4 | 0 | 4 |
| ESRRA | SFTPC | 0.65392 | 4 | 0 | 3 |
| ESRRA | RNF44 | 0.65287 | 3 | 0 | 3 |
| ESRRA | NANOS2 | 0.647901 | 4 | 0 | 4 |
For details and further investigation, click here
