| Full name: ligand dependent nuclear receptor corepressor like | Alias Symbol: MLR1|FLJ30696 | ||
| Type: protein-coding gene | Cytoband: 4p15.31 | ||
| Entrez ID: 254251 | HGNC ID: HGNC:30776 | Ensembl Gene: ENSG00000178177 | OMIM ID: 611799 |
| Drug and gene relationship at DGIdb | |||
Expression of LCORL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LCORL | 254251 | 240592_at | 0.4384 | 0.3962 | |
| GSE26886 | LCORL | 254251 | 240592_at | -0.6702 | 0.0616 | |
| GSE45670 | LCORL | 254251 | 240592_at | 0.0886 | 0.6916 | |
| GSE53622 | LCORL | 254251 | 60657 | 0.0197 | 0.8263 | |
| GSE53624 | LCORL | 254251 | 60657 | -0.1632 | 0.0058 | |
| GSE63941 | LCORL | 254251 | 240592_at | -0.4375 | 0.4321 | |
| GSE77861 | LCORL | 254251 | 240592_at | -0.2598 | 0.1815 | |
| GSE97050 | LCORL | 254251 | A_33_P3333890 | 0.0478 | 0.8918 | |
| SRP007169 | LCORL | 254251 | RNAseq | -0.4374 | 0.3825 | |
| SRP008496 | LCORL | 254251 | RNAseq | -0.5583 | 0.0937 | |
| SRP064894 | LCORL | 254251 | RNAseq | 0.1623 | 0.4201 | |
| SRP133303 | LCORL | 254251 | RNAseq | -0.2275 | 0.1320 | |
| SRP159526 | LCORL | 254251 | RNAseq | -0.0940 | 0.7827 | |
| SRP193095 | LCORL | 254251 | RNAseq | -0.7285 | 0.0000 | |
| SRP219564 | LCORL | 254251 | RNAseq | 0.0621 | 0.8938 | |
| TCGA | LCORL | 254251 | RNAseq | -0.2107 | 0.0083 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LCORL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LCORL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LCORL | 254251 | 0 | 18 | 12 | |
| GSE20123 | LCORL | 254251 | 0 | 18 | 12 | |
| GSE43470 | LCORL | 254251 | 1 | 15 | 27 | |
| GSE46452 | LCORL | 254251 | 1 | 36 | 22 | |
| GSE47630 | LCORL | 254251 | 1 | 19 | 20 | |
| GSE54993 | LCORL | 254251 | 9 | 0 | 61 | |
| GSE54994 | LCORL | 254251 | 4 | 12 | 37 | |
| GSE60625 | LCORL | 254251 | 0 | 0 | 11 | |
| GSE74703 | LCORL | 254251 | 1 | 13 | 22 | |
| GSE74704 | LCORL | 254251 | 0 | 11 | 9 | |
| TCGA | LCORL | 254251 | 8 | 49 | 39 |
Total number of gains: 25; Total number of losses: 191; Total Number of normals: 272.
Somatic mutations of LCORL:
Generating mutation plots.
Highly correlated genes for LCORL:
Showing top 20/46 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LCORL | BCAP31 | 0.740045 | 3 | 0 | 3 |
| LCORL | DGAT2 | 0.720655 | 3 | 0 | 3 |
| LCORL | GPR180 | 0.709261 | 3 | 0 | 3 |
| LCORL | AACS | 0.708392 | 3 | 0 | 3 |
| LCORL | CEP135 | 0.703532 | 3 | 0 | 3 |
| LCORL | ESRRA | 0.702559 | 3 | 0 | 3 |
| LCORL | C5orf30 | 0.688782 | 3 | 0 | 3 |
| LCORL | ARL11 | 0.682961 | 3 | 0 | 3 |
| LCORL | FANK1 | 0.674942 | 3 | 0 | 3 |
| LCORL | TFAP2C | 0.672538 | 4 | 0 | 3 |
| LCORL | ARFGEF1 | 0.663058 | 3 | 0 | 3 |
| LCORL | ZNF326 | 0.658572 | 3 | 0 | 3 |
| LCORL | PABPC1 | 0.656141 | 4 | 0 | 3 |
| LCORL | MAL2 | 0.655729 | 3 | 0 | 3 |
| LCORL | IL22RA2 | 0.647603 | 3 | 0 | 3 |
| LCORL | CD46 | 0.645544 | 3 | 0 | 3 |
| LCORL | ENTPD5 | 0.644413 | 3 | 0 | 3 |
| LCORL | TFCP2L1 | 0.639529 | 3 | 0 | 3 |
| LCORL | PRSS16 | 0.621336 | 4 | 0 | 4 |
| LCORL | SHQ1 | 0.618945 | 4 | 0 | 3 |
For details and further investigation, click here
