| Full name: Fas associated factor 1 | Alias Symbol: CGI-03|hFAF1|HFAF1s|UBXD12|UBXN3A | ||
| Type: protein-coding gene | Cytoband: 1p32.3 | ||
| Entrez ID: 11124 | HGNC ID: HGNC:3578 | Ensembl Gene: ENSG00000185104 | OMIM ID: 604460 |
| Drug and gene relationship at DGIdb | |||
Expression of FAF1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAF1 | 11124 | 218080_x_at | 0.1774 | 0.6862 | |
| GSE20347 | FAF1 | 11124 | 218080_x_at | 0.0765 | 0.7461 | |
| GSE23400 | FAF1 | 11124 | 218080_x_at | 0.0811 | 0.1591 | |
| GSE26886 | FAF1 | 11124 | 218080_x_at | 0.7068 | 0.0019 | |
| GSE29001 | FAF1 | 11124 | 218080_x_at | 0.0022 | 0.9957 | |
| GSE38129 | FAF1 | 11124 | 218080_x_at | 0.1212 | 0.3920 | |
| GSE45670 | FAF1 | 11124 | 224217_s_at | -0.1347 | 0.2655 | |
| GSE53622 | FAF1 | 11124 | 22720 | -0.4797 | 0.0000 | |
| GSE53624 | FAF1 | 11124 | 22720 | -0.1801 | 0.0002 | |
| GSE63941 | FAF1 | 11124 | 218080_x_at | 0.8219 | 0.0113 | |
| GSE77861 | FAF1 | 11124 | 218080_x_at | -0.4237 | 0.0383 | |
| GSE97050 | FAF1 | 11124 | A_23_P96853 | 0.8185 | 0.2685 | |
| SRP007169 | FAF1 | 11124 | RNAseq | -0.0106 | 0.9791 | |
| SRP008496 | FAF1 | 11124 | RNAseq | -0.0150 | 0.9497 | |
| SRP064894 | FAF1 | 11124 | RNAseq | -0.1238 | 0.3625 | |
| SRP133303 | FAF1 | 11124 | RNAseq | -0.0638 | 0.6423 | |
| SRP159526 | FAF1 | 11124 | RNAseq | -0.0413 | 0.9030 | |
| SRP193095 | FAF1 | 11124 | RNAseq | -0.1721 | 0.0242 | |
| SRP219564 | FAF1 | 11124 | RNAseq | 0.0308 | 0.9260 | |
| TCGA | FAF1 | 11124 | RNAseq | 0.0341 | 0.4793 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAF1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAF1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAF1 | 11124 | 3 | 4 | 23 | |
| GSE20123 | FAF1 | 11124 | 3 | 3 | 24 | |
| GSE43470 | FAF1 | 11124 | 5 | 4 | 34 | |
| GSE46452 | FAF1 | 11124 | 2 | 1 | 56 | |
| GSE47630 | FAF1 | 11124 | 8 | 4 | 28 | |
| GSE54993 | FAF1 | 11124 | 0 | 1 | 69 | |
| GSE54994 | FAF1 | 11124 | 11 | 2 | 40 | |
| GSE60625 | FAF1 | 11124 | 0 | 0 | 11 | |
| GSE74703 | FAF1 | 11124 | 4 | 2 | 30 | |
| GSE74704 | FAF1 | 11124 | 2 | 0 | 18 | |
| TCGA | FAF1 | 11124 | 10 | 21 | 65 |
Total number of gains: 48; Total number of losses: 42; Total Number of normals: 398.
Somatic mutations of FAF1:
Generating mutation plots.
Highly correlated genes for FAF1:
Showing top 20/136 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAF1 | IFT52 | 0.731476 | 3 | 0 | 3 |
| FAF1 | FOXA1 | 0.709197 | 3 | 0 | 3 |
| FAF1 | FAM161A | 0.694017 | 3 | 0 | 3 |
| FAF1 | MRPL43 | 0.675775 | 4 | 0 | 3 |
| FAF1 | BUD31 | 0.670151 | 5 | 0 | 3 |
| FAF1 | POP5 | 0.669513 | 4 | 0 | 3 |
| FAF1 | ZSCAN25 | 0.661168 | 3 | 0 | 3 |
| FAF1 | EFCAB7 | 0.659683 | 3 | 0 | 3 |
| FAF1 | PXN-AS1 | 0.658548 | 3 | 0 | 3 |
| FAF1 | RNF157-AS1 | 0.650467 | 4 | 0 | 3 |
| FAF1 | MRPL37 | 0.650104 | 4 | 0 | 3 |
| FAF1 | USP24 | 0.649182 | 10 | 0 | 8 |
| FAF1 | ZNF165 | 0.647496 | 4 | 0 | 3 |
| FAF1 | TSNARE1 | 0.645052 | 3 | 0 | 3 |
| FAF1 | MTOR | 0.644239 | 6 | 0 | 4 |
| FAF1 | ZNF311 | 0.642236 | 4 | 0 | 3 |
| FAF1 | PTGES3 | 0.641743 | 4 | 0 | 3 |
| FAF1 | NDC1 | 0.639899 | 7 | 0 | 4 |
| FAF1 | MTO1 | 0.636613 | 3 | 0 | 3 |
| FAF1 | MRPS15 | 0.636584 | 8 | 0 | 7 |
For details and further investigation, click here
